Europe PMC requires Javascript to function effectively.

Either your web browser doesn't support Javascript or it is currently turned off. In the latter case, please turn on Javascript support in your web browser and reload this page.

Search life-sciences literature (45,100,050 articles, preprints and more)

Search results

1-25 of 87 results

Sort by:

Relevance ^{Relevance: This is determined based on a ranking of criteria including term frequency, rarity of term, recency of article, whether there is a Title or Author field match, etc.}

Times cited

Date

1 2 3 Next ...

Genetic links between ovarian ageing, cancer risk and de novo mutation rates.
Stankovic S, Shekari S, Huang QQ, Gardner EJ, Ivarsdottir EV, Owens NDL, Mavaddat N, Azad A, Hawkes G, Kentistou KA, Beaumont RN, Day FR, Zhao Y, Jonsson H, Rafnar T, Tragante V, Sveinbjornsson G, Oddsson A, Styrkarsdottir U, [...] Murray A
Nature, 633(8030):608-614, 11 Sep 2024
Cited by: 1 article | PMID: 39261734 | PMCID: PMC11410666
Add to export list
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
Colorectal cancer risk stratification using a polygenic risk score in symptomatic primary care patients-a UK Biobank retrospective cohort study.
Mallabar-Rimmer B, Merriel SWD, Webster AP, Jackson L, Wood AR, Barclay M, Tyrrell J, Ruth KS, Thirlwell C, Oram R, Weedon MN, Bailey SER, Green HD
Eur J Hum Genet, 01 Aug 2024
Cited by: 0 articles | PMID: 39090236
Add to export list
Genomic and proteomic evidence for hormonal and metabolic foundations of polycystic ovary syndrome
Moolhuijsen LM, Zhu J, Mullin BH, Pujol-Gualdo N, Actkins KV, Mack JA, Rao H, Trivedi B, Kentistou KA, Zhao Y, Westergard D, Tyrmi JS, Thorleifsson G, Zhang Y, Wittemans L, DeVries A, Brewer K, Sisk R, Danning R, [...] Day FR
medRxiv, 19 Apr 2024
Cited by: 0 articles | PPR: PPR840069
Add to export list Preprint
Response to Penetrance estimates of hereditary cancers in a population setting using UK Biobank data.
Jackson L, Weedon MN, Green HD, Mallabar-Rimmer B, Harrison JW, Wood AR, Ruth KS, Tyrrell J, Wright CF
BJC Rep, 2(1):25, 15 Mar 2024
Cited by: 0 articles | PMID: 39516645 | PMCID: PMC11523980
Add to export list
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
Colorectal cancer risk stratification using a polygenic risk score in symptomatic patients presenting to primary care – a UK Biobank retrospective cohort study
Mallabar-Rimmer B, Merriel SW, Webster AP, Wood AR, Barclay M, Tyrrell J, Ruth KS, Thirlwell C, Oram R, Weedon MN, Bailey SE, Green HD
medRxiv, 09 Dec 2023
Cited by: 0 articles | PPR: PPR771670
Add to export list Preprint
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
Insights into the genetics of menopausal vasomotor symptoms: genome-wide analyses of routinely-collected primary care health records.
Ruth KS, Beaumont RN, Locke JM, Tyrrell J, Crandall CJ, Hawkes G, Frayling TM, Prague JK, Patel KA, Wood AR, Weedon MN, Murray A
BMC Med Genomics, 16(1):231, 02 Oct 2023
Cited by: 0 articles | PMID: 37784116 | PMCID: PMC10546673
Add to export list
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
Menopause age, reproductive span and hormone therapy duration predict the volume of medial temporal lobe brain structures in postmenopausal women.
Steventon JJ, Lancaster TM, Baker ES, Bracher-Smith M, Escott-Price V, Ruth KS, Davies W, Caseras X, Murphy K
Psychoneuroendocrinology, 158:106393, 18 Sep 2023
Cited by: 2 articles | PMID: 37774659
Add to export list
Influence of family history on penetrance of hereditary cancers in a population setting.
Jackson L, Weedon MN, Green HD, Mallabar-Rimmer B, Harrison JW, Wood AR, Ruth KS, Tyrrell J, Wright CF
EClinicalMedicine, 64:102159, 14 Sep 2023
Cited by: 9 articles | PMID: 37936660 | PMCID: PMC10626157
Add to export list
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
Penetrance of pathogenic genetic variants associated with premature ovarian insufficiency.
Shekari S, Stankovic S, Gardner EJ, Hawkes G, Kentistou KA, Beaumont RN, Mörseburg A, Wood AR, Prague JK, Mishra GD, Day FR, Baptista J, Wright CF, Weedon MN, Hoffmann ER, Ruth KS, Ong KK, Perry JRB, Murray A
Nat Med, 29(7):1692-1699, 22 Jun 2023
Cited by: 9 articles | PMID: 37349538
Add to export list
Genetically proxied therapeutic prolyl-hydroxylase inhibition and cardiovascular risk.
Harlow CE, Patel VV, Waterworth DM, Wood AR, Beaumont RN, Ruth KS, Tyrrell J, Oguro-Ando A, Chu AY, Frayling TM
Hum Mol Genet, 32(3):496-505, 01 Jan 2023
Cited by: 0 articles | PMID: 36048866 | PMCID: PMC9851745
Add to export list
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
Response to: Genetic risk scores may compound rather than solve the issue of prostate cancer overdiagnosis (BJC-LT3342090).
Green HD, Merriel SWD, Oram RA, Ruth KS, Tyrrell J, Jones SE, Thirlwell C, Weedon MN, Bailey SER
Br J Cancer, 128(4):487-488, 19 Dec 2022
Cited by: 0 articles | PMID: 36536048 | PMCID: PMC9938192
Add to export list Free full text in Europe PMC
Monogenic causes of Premature Ovarian Insufficiency are rare and mostly recessive
Shekari S, Stankovic S, Gardner EJ, Hawkes G, Kentistou KA, Beaumont RN, Mörseburg A, Wood AR, Mishra G, Day F, Baptista J, Wright CF, Weedon MN, Hoffmann E, Ruth KS, Ong K, Perry JRB, Murray A
medRxiv, 22 Nov 2022
Cited by: 0 articles | PPR: PPR574253
Add to export list Preprint
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
Applying a genetic risk score for prostate cancer to men with lower urinary tract symptoms in primary care to predict prostate cancer diagnosis: a cohort study in the UK Biobank.
Green HD, Merriel SWD, Oram RA, Ruth KS, Tyrrell J, Jones SE, Thirlwell C, Weedon MN, Bailey SER
Br J Cancer, 127(8):1534-1539, 18 Aug 2022
Cited by: 16 articles | PMID: 35978138 | PMCID: PMC9553867
Add to export list
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
Study of the associations between short telomeres, sex hormones and pulmonary fibrosis
Duckworth A, Ruth KS, Prague JK, Russell A, Almond H, Conway J, Beaumont RN, Wood AR, Martin S, Lunnon K, Lindsay MA, Murray A, Gibbons MA, Tyrrell J, Scotton CJ
medRxiv, 30 Sep 2022
Cited by: 0 articles | PPR: PPR552753
Add to export list Preprint
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
Influence of family history on penetrance of hereditary cancers in a population setting
Jackson L, Weedon M, Harrison J, Wood A, Ruth K, Tyrrell J, Wright C
medRxiv, 09 Jul 2022
Cited by: 0 articles | PPR: PPR515782
Add to export list Preprint
Genetic susceptibility to earlier ovarian ageing increases de novo mutation rate in offspring
Stankovic S, Shekari S, Huang QQ, Gardner EJ, Owens NDL, Azad A, Hawkes G, Kentistou KA, Beaumont RN, Day FR, Zhao Y, The Genomics England Research Consortium, Kennedy K, Wood AR, Weedon MN, Ong KK, Wright CF, Hoffmann ER, Hurles ME, [...] Murray A
medRxiv, 23 Jun 2022
Cited by: 0 articles | PPR: PPR509678
Add to export list Preprint
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
Detection and characterization of male sex chromosome abnormalities in the UK Biobank study.
Zhao Y, Gardner EJ, Tuke MA, Zhang H, Pietzner M, Koprulu M, Jia RY, Ruth KS, Wood AR, Beaumont RN, Tyrrell J, Jones SE, Lango Allen H, Day FR, Langenberg C, Frayling TM, Weedon MN, Perry JRB, Ong KK, Murray A
Genet Med, 24(9):1909-1919, 09 Jun 2022
Cited by: 16 articles | PMID: 35687092
Add to export list
Genome-wide association study meta-analysis identifies three novel loci for circulating anti-Müllerian hormone levels in women.
Verdiesen RMG, van der Schouw YT, van Gils CH, Verschuren WMM, Broekmans FJM, Borges MC, Gonçalves Soares AL, Lawlor DA, Eliassen AH, Kraft P, Sandler DP, Harlow SD, Smith JA, Santoro N, Schoemaker MJ, Swerdlow AJ, Murray A, Ruth KS, Onland-Moret NC
Hum Reprod, 37(5):1069-1082, 01 May 2022
Cited by: 15 articles | PMID: 35274129 | PMCID: PMC9071229
Add to export list
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
Identifying molecular mediators of the relationship between body mass index and endometrial cancer risk: a Mendelian randomization analysis.
Hazelwood E, Sanderson E, Tan VY, Ruth KS, Frayling TM, Dimou N, Gunter MJ, Dossus L, Newton C, Ryan N, Pournaras DJ, O'Mara TA, Davey Smith G, Martin RM, Yarmolinsky J
BMC Med, 20(1):125, 19 Apr 2022
Cited by: 25 articles | PMID: 35436960 | PMCID: PMC9017004
Add to export list
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
Genomic insights into the mechanism of NK3R antagonists for treatment of menopausal vasomotor symptoms
Ruth KS, Beaumont RN, Locke JM, Tyrrell J, Crandall CJ, Hawkes G, Frayling TM, Prague JK, Patel KA, Wood AR, Weedon MN, Murray A
medRxiv, 26 May 2022
Cited by: 0 articles | PPR: PPR499108
Add to export list Preprint
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
Applying a genetic risk score for prostate cancer to men with lower urinary tract symptoms in primary care to predict prostate cancer diagnosis: a cohort study in the UK Biobank
Green HD, Merriel SW, Oram RA, Ruth KS, Tyrrell J, Jones SE, Thirlwell C, Gillings M, Weedon MN, Bailey SE
medRxiv, 21 Jan 2022
Cited by: 0 articles | PPR: PPR445724
Add to export list Preprint
Identifying molecular mediators of the relationship between body mass index and endometrial cancer risk: a Mendelian randomization analysis
Hazelwood E, Sanderson E, Tan VY, Ruth KS, Frayling TM, Dimou N, Gunter MJ, Dossus L, Newton C, Ryan N, Pournaras DJ, O’Mara TA, Smith GD, Martin RM, Yarmolinsky J
medRxiv, 13 Dec 2021
Cited by: 0 articles | PPR: PPR431320
Add to export list Preprint
Do sex hormones confound or mediate the effect of chronotype on breast and prostate cancer? A Mendelian randomization study.
Hayes BL, Robinson T, Kar S, Ruth KS, Tsilidis KK, Frayling T, Murray A, Martin RM, Lawlor DA, Richmond RC
PLoS Genet, 18(1):e1009887, 21 Jan 2022
Cited by: 13 articles | PMID: 35061662 | PMCID: PMC8809575
Add to export list
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
Free full text in Europe PMC
Genetic insights into biological mechanisms governing human ovarian ageing.
Ruth KS, Day FR, Hussain J, Martínez-Marchal A, Aiken CE, Azad A, Thompson DJ, Knoblochova L, Abe H, Tarry-Adkins JL, Gonzalez JM, Fontanillas P, Claringbould A, Bakker OB, Sulem P, Walters RG, Terao C, Turon S, Horikoshi M, [...] Perry JRB
Nature, 596(7872):393-397, 04 Aug 2021
Cited by: 137 articles | PMID: 34349265 | PMCID: PMC7611832
Add to export list Free full text in Europe PMC
Do sex hormones confound or mediate the effect of chronotype on breast and prostate cancer? A Mendelian randomization study
Hayes B, Robinson T, Kar S, Ruth KS, Tsilidis KK, Frayling T, Murray A, Martin RM, Lawlor DA, Richmond RC
medRxiv, 21 Apr 2021
Cited by: 0 articles | PPR: PPR315017
Add to export list Preprint

1-25 of 87 results

1 2 3 Next ...

Search life-sciences literature (45,100,050 articles, preprints and more)

Search results

Genetic links between ovarian ageing, cancer risk and de novo mutation rates.

Colorectal cancer risk stratification using a polygenic risk score in symptomatic primary care patients-a UK Biobank retrospective cohort study.

Genomic and proteomic evidence for hormonal and metabolic foundations of polycystic ovary syndrome

Response to Penetrance estimates of hereditary cancers in a population setting using UK Biobank data.

Colorectal cancer risk stratification using a polygenic risk score in symptomatic patients presenting to primary care – a UK Biobank retrospective cohort study

Insights into the genetics of menopausal vasomotor symptoms: genome-wide analyses of routinely-collected primary care health records.

Menopause age, reproductive span and hormone therapy duration predict the volume of medial temporal lobe brain structures in postmenopausal women.

Influence of family history on penetrance of hereditary cancers in a population setting.

Penetrance of pathogenic genetic variants associated with premature ovarian insufficiency.

Genetically proxied therapeutic prolyl-hydroxylase inhibition and cardiovascular risk.

Response to: Genetic risk scores may compound rather than solve the issue of prostate cancer overdiagnosis (BJC-LT3342090).

Monogenic causes of Premature Ovarian Insufficiency are rare and mostly recessive

Applying a genetic risk score for prostate cancer to men with lower urinary tract symptoms in primary care to predict prostate cancer diagnosis: a cohort study in the UK Biobank.

Study of the associations between short telomeres, sex hormones and pulmonary fibrosis

Influence of family history on penetrance of hereditary cancers in a population setting

Genetic susceptibility to earlier ovarian ageing increases de novo mutation rate in offspring

Detection and characterization of male sex chromosome abnormalities in the UK Biobank study.

Genome-wide association study meta-analysis identifies three novel loci for circulating anti-Müllerian hormone levels in women.

Identifying molecular mediators of the relationship between body mass index and endometrial cancer risk: a Mendelian randomization analysis.

Genomic insights into the mechanism of NK3R antagonists for treatment of menopausal vasomotor symptoms

Applying a genetic risk score for prostate cancer to men with lower urinary tract symptoms in primary care to predict prostate cancer diagnosis: a cohort study in the UK Biobank

Identifying molecular mediators of the relationship between body mass index and endometrial cancer risk: a Mendelian randomization analysis

Do sex hormones confound or mediate the effect of chronotype on breast and prostate cancer? A Mendelian randomization study.

Genetic insights into biological mechanisms governing human ovarian ageing.

Do sex hormones confound or mediate the effect of chronotype on breast and prostate cancer? A Mendelian randomization study

Partnerships & funding