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Search life-sciences literature (45,104,145 articles, preprints and more)

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Endothelial c-Myc knockout disrupts metabolic homeostasis and triggers the development of obesity.
Machi JF, Altilio I, Qi Y, Morales AA, Silvestre DH, Hernandez DR, Da Costa-Santos N, Santana AG, Neghabi M, Nategh P, Castro TL, Werneck-de-Castro JP, Ranji M, Evangelista FS, Vazquez-Padron RI, Bernal-Mizrachi E, Rodrigues CO
Front Cell Dev Biol, 12:1407097, 19 Jul 2024
Cited by: 1 article | PMID: 39100099 | PMCID: PMC11294153
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c-Myc Drives inflammation of the maternal-fetal interface, and neonatal lung remodeling induced by intra-amniotic inflammation.
Tan AW, Tong X, Alvarez-Cubela S, Chen P, Santana AG, Morales AA, Tian R, Infante R, Nunes de Paiva V, Kulandavelu S, Benny M, Dominguez-Bendala J, Wu S, Young KC, Rodrigues CO, Schmidt AF
Front Cell Dev Biol, 11:1245747, 28 Feb 2024
Cited by: 0 articles | PMID: 38481391 | PMCID: PMC10933046
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Illuminating a Solvent-Dependent Hierarchy for Aromatic CH/π Complexes with Dynamic Covalent Glyco-Balances.
Díaz-Casado L, Villacampa A, Corzana F, Jiménez-Barbero J, Gómez AM, Santana AG, Asensio JL
JACS Au, 4(2):476-490, 02 Jan 2024
Cited by: 0 articles | PMID: 38425929 | PMCID: PMC10900200
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In Vitro Culture and Phytochemical Analysis of Diospyros Anisandra
Santana AGA, Pool FB, Alamillo MAH, Erosa FE, Llañez MAK, Castano E, Argaez RB, Rodriguez-Zapata LC
Research Square, 11 Apr 2023
Cited by: 0 articles | PPR: PPR643723
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Binding-driven reactivity attenuation enables NMR identification of selective drug candidates for nucleic acid targets.
Díaz-Casado L, Santana AG, Gómez-Pinto I, Villacampa A, Corzana F, Jiménez-Barbero J, González C, Asensio JL
Commun Chem, 5(1):137, 27 Oct 2022
Cited by: 0 articles | PMID: 36697799 | PMCID: PMC9814457
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Synthesis and Characterization of a Novel Resveratrol Xylobioside Obtained Using a Mutagenic Variant of a GH10 Endoxylanase.
Pozo-Rodríguez A, Méndez-Líter JA, García-Villalba R, Beltrán D, Calviño E, Santana AG, de Eugenio LI, Cañada FJ, Prieto A, Barriuso J, Tomás-Barberán FA, Martínez MJ
Antioxidants (Basel), 12(1):85, 30 Dec 2022
Cited by: 1 article | PMID: 36670947 | PMCID: PMC9855058
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Pharmacological Chaperones for GCase that Switch Conformation with pH Enhance Enzyme Levels in Gaucher Animal Models.
Santana AG, Robinson K, Vickers C, Deen MC, Chen HM, Zhou S, Dai B, Fuller M, Boraston AB, Vocadlo DJ, Clarke LA, Withers SG
Angew Chem Int Ed Engl, 61(38):e202207974, 12 Aug 2022
Cited by: 2 articles | PMID: 35864061
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Glycosylation of Epigallocatechin Gallate by Engineered Glycoside Hydrolases from Talaromyces amestolkiae: Potential Antiproliferative and Neuroprotective Effect of These Molecules.
Méndez-Líter JA, Pozo-Rodríguez A, Madruga E, Rubert M, Santana AG, de Eugenio LI, Sánchez C, Martínez A, Prieto A, Martínez MJ
Antioxidants (Basel), 11(7):1325, 05 Jul 2022
Cited by: 5 articles | PMID: 35883816 | PMCID: PMC9312355
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A Fungal Versatile GH10 Endoxylanase and Its Glycosynthase Variant: Synthesis of Xylooligosaccharides and Glycosides of Bioactive Phenolic Compounds.
Pozo-Rodríguez A, Méndez-Líter JA, de Eugenio LI, Nieto-Domínguez M, Calviño E, Cañada FJ, Santana AG, Díez J, Asensio JL, Barriuso J, Prieto A, Martínez MJ
Int J Mol Sci, 23(3):1383, 26 Jan 2022
Cited by: 2 articles | PMID: 35163307 | PMCID: PMC8836076
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Intramolecular Metal-Free C(sp³)-H Activation Enables a Selective Mono O-Debenzylation of Fully Protected Aminosugars.
Santana AG, Herrera AJ, González CC
J Org Chem, 86(23):16736-16752, 22 Nov 2021
Cited by: 0 articles | PMID: 34807601
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Aromatic Interactions in Glycochemistry: From Molecular Recognition to Catalysis.
Santana AG, Díaz-Casado L, Montalvillo L, Jiménez-Moreno E, Mann E, Asensio JL
Curr Med Chem, 29(7):1208-1218, 01 Jan 2022
Cited by: 0 articles | PMID: 34254906
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Lipid-mimicking phosphorus-based glycosidase inactivators as pharmacological chaperones for the treatment of Gaucher's disease.
Scherer M, Santana AG, Robinson K, Zhou S, Overkleeft HS, Clarke L, Withers SG
Chem Sci, 12(41):13909-13913, 20 Sep 2021
Cited by: 4 articles | PMID: 34760177 | PMCID: PMC8549773
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De Novo Design of Selective Quadruplex-Duplex Junction Ligands and Structural Characterisation of Their Binding Mode: Targeting the G4 Hot-Spot.
Díaz-Casado L, Serrano-Chacón I, Montalvillo-Jiménez L, Corzana F, Bastida A, Santana AG, González C, Asensio JL
Chemistry, 27(20):6106, 22 Feb 2021
Cited by: 1 article | PMID: 33615580
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De Novo Design of Selective Quadruplex-Duplex Junction Ligands and Structural Characterisation of Their Binding Mode: Targeting the G4 Hot-Spot.
Díaz-Casado L, Serrano-Chacón I, Montalvillo-Jiménez L, Corzana F, Bastida A, Santana AG, González C, Asensio JL
Chemistry, 27(20):6204-6212, 22 Jan 2021
Cited by: 12 articles | PMID: 33368678
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Tandem Radical Fragmentation/Cyclization of Guanidinylated Monosaccharides Grants Access to Medium-Sized Polyhydroxylated Heterocycles.
Santana AG, González CC
Org Lett, 22(21):8492-8495, 19 Oct 2020
Cited by: 3 articles | PMID: 33074675
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Single-Step Glycosylations with ¹³ C-Labelled Sulfoxide Donors: A Low-Temperature NMR Cartography of the Distinguishing Mechanistic Intermediates.
Santana AG, Montalvillo-Jiménez L, Díaz-Casado L, Mann E, Jiménez-Barbero J, Gómez AM, Asensio JL
Chemistry, 27(6):2030-2042, 23 Nov 2020
Cited by: 7 articles | PMID: 32969069
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Thioglycoligase derived from fungal GH3 β-xylosidase is a multi-glycoligase with broad acceptor tolerance.
Nieto-Domínguez M, Fernández de Toro B, de Eugenio LI, Santana AG, Bejarano-Muñoz L, Armstrong Z, Méndez-Líter JA, Asensio JL, Prieto A, Withers SG, Cañada FJ, Martínez MJ
Nat Commun, 11(1):4864, 25 Sep 2020
Cited by: 10 articles | PMID: 32978392 | PMCID: PMC7519651
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ADAM17 cytoplasmic domain modulates Thioredoxin-1 conformation and activity.
E Costa RAP, Granato DC, Trino LD, Yokoo S, Carnielli CM, Kawahara R, Domingues RR, Pauletti BA, Neves LX, Santana AG, Paulo JA, Aragão AZB, Heleno Batista FA, Migliorini Figueira AC, Laurindo FRM, Fernandes D, Hansen HP, Squina F, Gygi SP, Paes Leme AF
Redox Biol, 37:101735, 24 Sep 2020
Cited by: 3 articles | PMID: 33011677 | PMCID: PMC7513893
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Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C-5a-Substituted Derivatives of 4-epi-Isofagomine.
Weber P, Thonhofer M, Averill S, Davies GJ, Santana AG, Müller P, Nasseri SA, Offen WA, Pabst BM, Paschke E, Schalli M, Torvisco A, Tschernutter M, Tysoe C, Windischhofer W, Withers SG, Wolfsgruber A, Wrodnigg TM, Stütz AE
Molecules, 25(17):E4025, 03 Sep 2020
Cited by: 1 article | PMID: 32899288 | PMCID: PMC7504770
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Corrigendum: Facile Formation of β-thioGlcNAc Linkages to Thiol-Containing Sugars, Peptides, and Proteins using a Mutant GH20 Hexosaminidase.
Zhao J, Si Y, Han Z, Li J, Guo W, Fu Y, Tegl G, Hanson J, Chen HM, Kwan DH, Santana AG, Withers SG
Angew Chem Int Ed Engl, 59(23):8752, 18 Mar 2020
Cited by: 0 articles | PMID: 32449594 | PMCID: PMC8097562
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Dissecting the Essential Role of Anomeric β-Triflates in Glycosylation Reactions.
Santana AG, Montalvillo-Jiménez L, Díaz-Casado L, Corzana F, Merino P, Cañada FJ, Jiménez-Osés G, Jiménez-Barbero J, Gómez AM, Asensio JL
J Am Chem Soc, 142(28):12501-12514, 06 Jul 2020
Cited by: 17 articles | PMID: 32579343
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A glucotolerant b-glucosidase from the fungus Talaromyces amestolkiae and its conversion into a glycosynthase for glycosylation of phenolic compounds
Méndez-Líter JA, Nieto-Domínguez M, de Toro BF, Santana AG, Prieto A, Asensio JL, Cañada FJ, de Eugenio LI, Martinez MJ
Research Square, 31 Mar 2020
Cited by: 0 articles | PPR: PPR134446
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Impact of Aromatic Stacking on Glycoside Reactivity: Balancing CH/π and Cation/π Interactions for the Stabilization of Glycosyl-Oxocarbenium Ions.
Montalvillo-Jiménez L, Santana AG, Corzana F, Jiménez-Osés G, Jiménez-Barbero J, Gómez AM, Asensio JL
J Am Chem Soc, 141(34):13372-13384, 20 Aug 2019
Cited by: 12 articles | PMID: 31390207
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Synthesis of Ring II/III Fragment of Kanamycin: A New Minimum Structural Motif for Aminoglycoside Recognition.
Zárate SG, Bastida A, Santana AG, Revuelta J
Antibiotics (Basel), 8(3):E109, 02 Aug 2019
Cited by: 1 article | PMID: 31382490 | PMCID: PMC6783941
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Synthesis of Chiral Polyhydroxylated Benzimidazoles by a Tandem Radical Fragmentation/Cyclization Reaction: A Straight Avenue to Fused Aromatic-Carbohydrate Hybrids.
André-Joyaux E, Santana AG, González CC
J Org Chem, 84(2):506-515, 09 Jan 2019
Cited by: 2 articles | PMID: 30589268
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1-25 of 47 results

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Search life-sciences literature (45,104,145 articles, preprints and more)

Search results

Endothelial c-Myc knockout disrupts metabolic homeostasis and triggers the development of obesity.

c-Myc Drives inflammation of the maternal-fetal interface, and neonatal lung remodeling induced by intra-amniotic inflammation.

Illuminating a Solvent-Dependent Hierarchy for Aromatic CH/π Complexes with Dynamic Covalent Glyco-Balances.

In Vitro Culture and Phytochemical Analysis of Diospyros Anisandra

Binding-driven reactivity attenuation enables NMR identification of selective drug candidates for nucleic acid targets.

Synthesis and Characterization of a Novel Resveratrol Xylobioside Obtained Using a Mutagenic Variant of a GH10 Endoxylanase.

Pharmacological Chaperones for GCase that Switch Conformation with pH Enhance Enzyme Levels in Gaucher Animal Models.

Glycosylation of Epigallocatechin Gallate by Engineered Glycoside Hydrolases from Talaromyces amestolkiae: Potential Antiproliferative and Neuroprotective Effect of These Molecules.

A Fungal Versatile GH10 Endoxylanase and Its Glycosynthase Variant: Synthesis of Xylooligosaccharides and Glycosides of Bioactive Phenolic Compounds.

Intramolecular Metal-Free C(sp³)-H Activation Enables a Selective Mono O-Debenzylation of Fully Protected Aminosugars.

Aromatic Interactions in Glycochemistry: From Molecular Recognition to Catalysis.

Lipid-mimicking phosphorus-based glycosidase inactivators as pharmacological chaperones for the treatment of Gaucher's disease.

De Novo Design of Selective Quadruplex-Duplex Junction Ligands and Structural Characterisation of Their Binding Mode: Targeting the G4 Hot-Spot.

De Novo Design of Selective Quadruplex-Duplex Junction Ligands and Structural Characterisation of Their Binding Mode: Targeting the G4 Hot-Spot.

Tandem Radical Fragmentation/Cyclization of Guanidinylated Monosaccharides Grants Access to Medium-Sized Polyhydroxylated Heterocycles.

Single-Step Glycosylations with ¹³ C-Labelled Sulfoxide Donors: A Low-Temperature NMR Cartography of the Distinguishing Mechanistic Intermediates.

Thioglycoligase derived from fungal GH3 β-xylosidase is a multi-glycoligase with broad acceptor tolerance.

ADAM17 cytoplasmic domain modulates Thioredoxin-1 conformation and activity.

Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C-5a-Substituted Derivatives of 4-epi-Isofagomine.

Corrigendum: Facile Formation of β-thioGlcNAc Linkages to Thiol-Containing Sugars, Peptides, and Proteins using a Mutant GH20 Hexosaminidase.

Dissecting the Essential Role of Anomeric β-Triflates in Glycosylation Reactions.

A glucotolerant b-glucosidase from the fungus Talaromyces amestolkiae and its conversion into a glycosynthase for glycosylation of phenolic compounds

Impact of Aromatic Stacking on Glycoside Reactivity: Balancing CH/π and Cation/π Interactions for the Stabilization of Glycosyl-Oxocarbenium Ions.

Synthesis of Ring II/III Fragment of Kanamycin: A New Minimum Structural Motif for Aminoglycoside Recognition.

Synthesis of Chiral Polyhydroxylated Benzimidazoles by a Tandem Radical Fragmentation/Cyclization Reaction: A Straight Avenue to Fused Aromatic-Carbohydrate Hybrids.

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