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Search life-sciences literature (45,100,050 articles, preprints and more)

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CelLink: Integrate single-cell multi-omics data with few linked features and imbalanced cell populations
Luo X, Huang Y, Tao Y, Feng F, Hopkirk A, Bate TS, Saunders DC, Orchard P, Robertson C, Shrestha S, Cartailler J, Parker SCJ, Brissova M, Liu J
bioRxiv, 11 Nov 2024
Cited by: 0 articles | PPR: PPR938266
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CNTools: A computational toolbox for cellular neighborhood analysis from multiplexed images.
Tao Y, Feng F, Luo X, Reihsmann CV, Hopkirk AL, Cartailler JP, Brissova M, Parker SCJ, Saunders DC, Liu J
PLoS Comput Biol, 20(8):e1012344, 28 Aug 2024
Cited by: 0 articles | PMID: 39196899 | PMCID: PMC11355562
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CD39 delineates chimeric antigen receptor regulatory T cell subsets with distinct cytotoxic & regulatory functions against human islets.
Wu X, Chen PI, Whitener RL, MacDougall MS, Coykendall VMN, Yan H, Kim YB, Harper W, Pathak S, Iliopoulou BP, Hestor A, Saunders DC, Spears E, Sévigny J, Maahs DM, Basina M, Sharp SA, Gloyn AL, Powers AC, [...] Meyer EH
Front Immunol, 15:1415102, 28 Jun 2024
Cited by: 1 article | PMID: 39007132
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Exocrine Pancreas in Type 1 and Type 2 Diabetes: Different Patterns of Fibrosis, Metaplasia, Angiopathy, and Adiposity.
Wright JJ, Eskaros A, Windon A, Bottino R, Jenkins R, Bradley AM, Aramandla R, Philips S, Kang H, Saunders DC, Brissova M, Powers AC
Diabetes, 73(7):1140-1152, 01 Jul 2024
Cited by: 0 articles | PMID: 37881846
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AnnoSpat annotates cell types and quantifies cellular arrangements from spatial proteomics.
Mongia A, Zohora FT, Burget NG, Zhou Y, Saunders DC, Wang YJ, Brissova M, Powers AC, Kaestner KH, Vahedi G, Naji A, Schwartz GW, Faryabi RB
Nat Commun, 15(1):3744, 03 May 2024
Cited by: 1 article | PMID: 38702321 | PMCID: PMC11068798
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Age-Not Just a Number in Youth Mental Health.
Saunders DC, Knapp FM, Veenstra-VanderWeele J
JAMA Psychiatry, 81(4):327-328, 01 Apr 2024
Cited by: 0 articles | PMID: 38294788
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Sociocultural Risk and Resilience in the Context of Adverse Childhood Experiences.
VanBronkhorst SB, Abraham E, Dambreville R, Ramos-Olazagasti MA, Wall M, Saunders DC, Monk C, Alegría M, Canino GJ, Bird H, Duarte CS
JAMA Psychiatry, 81(4):406-413, 01 Apr 2024
Cited by: 3 articles | PMID: 38150238
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Genetic risk converges on regulatory networks mediating early type 2 diabetes.
Walker JT, Saunders DC, Rai V, Chen HH, Orchard P, Dai C, Pettway YD, Hopkirk AL, Reihsmann CV, Tao Y, Fan S, Shrestha S, Varshney A, Petty LE, Wright JJ, Ventresca C, Agarwala S, Aramandla R, Poffenberger G, [...] Brissova M
Nature, 624(7992):621-629, 04 Dec 2023
Cited by: 10 articles | PMID: 38049589 | PMCID: PMC11374460
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Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging.
Quardokus EM, Saunders DC, McDonough E, Hickey JW, Werlein C, Surrette C, Rajbhandari P, Casals AM, Tian H, Lowery L, Neumann EK, Björklund F, Neelakantan TV, Croteau J, Wiblin AE, Fisher J, Livengood AJ, Dowell KG, Silverstein JC, [...] Radtke AJ
Nat Methods, 20(8):1174-1178, 19 Jul 2023
Cited by: 11 articles | PMID: 37468619 | PMCID: PMC10406602
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The human α cell in health and disease.
Pettway YD, Saunders DC, Brissova M
J Endocrinol, 258(1):e220298, 19 Jun 2023
Cited by: 3 articles | PMID: 37114672 | PMCID: PMC10428003
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Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes.
Zhu H, Wang G, Nguyen-Ngoc KV, Kim D, Miller M, Goss G, Kovsky J, Harrington AR, Saunders DC, Hopkirk AL, Melton R, Powers AC, Preissl S, Spagnoli FM, Gaulton KJ, Sander M
Dev Cell, 58(9):727-743.e11, 10 Apr 2023
Cited by: 19 articles | PMID: 37040771 | PMCID: PMC10175223
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Human pancreatic capillaries and nerve fibers persist in type 1 diabetes despite beta cell loss.
Richardson TM, Saunders DC, Haliyur R, Shrestha S, Cartailler JP, Reinert RB, Petronglo J, Bottino R, Aramandla R, Bradley AM, Jenkins R, Phillips S, Kang H, Human Pancreas Analysis Program, Caicedo A, Powers AC, Brissova M
Am J Physiol Endocrinol Metab, 324(3):E251-E267, 25 Jan 2023
Cited by: 5 articles | PMID: 36696598 | PMCID: PMC10027091
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Images From the Exeter Archival Diabetes Biobank Now Accessible via Pancreatlas.
Morgan NG, Richardson SJ, Powers AC, Saunders DC, Brissova M
Diabetes Care, 45(12):e174-e175, 01 Dec 2022
Cited by: 3 articles | PMID: 36239401 | PMCID: PMC9862522
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AnnoSpat annotates cell types and quantifies cellular arrangements from spatial proteomics
Mongia A, Saunders DC, Wang YJ, Brissova M, Powers AC, Kaestner KH, Vahedi G, Naji A, Schwartz GW, Faryabi RB
bioRxiv, 18 Jan 2023
Cited by: 0 articles | PPR: PPR598363
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RFX6-mediated dysregulation defines human β cell dysfunction in early type 2 diabetes
Walker JT, Saunders DC, Rai V, Dai C, Orchard P, Hopkirk AL, Reihsmann CV, Tao Y, Fan S, Shrestha S, Varshney A, Wright JJ, Pettway YD, Ventresca C, Agarwala S, Aramandla R, Poffenberger G, Jenkins R, Hart NJ, [...] Brissova M
bioRxiv, 17 Dec 2021
Cited by: 0 articles | PPR: PPR433535
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Combinatorial transcription factor profiles predict mature and functional human islet α and β cells.
Shrestha S, Saunders DC, Walker JT, Camunas-Soler J, Dai XQ, Haliyur R, Aramandla R, Poffenberger G, Prasad N, Bottino R, Stein R, Cartailler JP, Parker SC, MacDonald PE, Levy SE, Powers AC, Brissova M
JCI Insight, 6(18):e151621, 22 Sep 2021
Cited by: 22 articles | PMID: 34428183 | PMCID: PMC8492318
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From type 1 diabetes biology to therapy: The Human Islet Research Network.
Kaddis JS, Rouse L, Parent AV, Saunders DC, Shalev A, Stabler CL, Stoffers DA, Wagner BK, Niland JC
Mol Metab, 54:101283, 03 Jul 2021
Cited by: 2 articles | PMID: 34224917 | PMCID: PMC8711046
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The Human Islet: Mini-Organ With Mega-Impact.
Walker JT, Saunders DC, Brissova M, Powers AC
Endocr Rev, 42(5):605-657, 01 Sep 2021
Cited by: 38 articles | PMID: 33844836 | PMCID: PMC8476939
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SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells.
Coate KC, Cha J, Shrestha S, Wang W, Gonçalves LM, Almaça J, Kapp ME, Fasolino M, Morgan A, Dai C, Saunders DC, Bottino R, Aramandla R, Jenkins R, Stein R, Kaestner KH, Vahedi G, HPAP Consortium, Brissova M, Powers AC
Cell Metab, 32(6):1028-1040.e4, 13 Nov 2020
Cited by: 125 articles | PMID: 33207245 | PMCID: PMC7664344
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Combinatorial transcription factor profiles predict mature and functional human islet α and β cells
Shrestha S, Saunders DC, Walker JT, Camunas-Soler J, Dai X, Haliyur R, Aramandla R, Poffenberger G, Prasad N, Bottino R, Stein R, Cartailler J, Parker SCJ, MacDonald PE, Levy SE, Powers AC, Brissova M
bioRxiv, 24 Feb 2021
Cited by: 0 articles | PPR: PPR287857
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Coordinated interactions between endothelial cells and macrophages in the islet microenvironment promote β cell regeneration.
Saunders DC, Aamodt KI, Richardson TM, Hopkirk AJ, Aramandla R, Poffenberger G, Jenkins R, Flaherty DK, Prasad N, Levy SE, Powers AC, Brissova M
NPJ Regen Med, 6(1):22, 06 Apr 2021
Cited by: 12 articles | PMID: 33824346 | PMCID: PMC8024255
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Pancreatlas: Applying an Adaptable Framework to Map the Human Pancreas in Health and Disease.
Saunders DC, Messmer J, Kusmartseva I, Beery ML, Yang M, Atkinson MA, Powers AC, Cartailler JP, Brissova M
Patterns (N Y), 1(8):100120, 05 Oct 2020
Cited by: 9 articles | PMID: 33294866 | PMCID: PMC7691395
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SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 are Expressed in the Pancreas but are Not Enriched in Islet Endocrine Cells
Coate KC, Cha J, Shrestha S, Wang W, Gonçalves LM, Almaça J, Kapp ME, Fasolino M, Morgan A, Dai C, Saunders DC, Bottino R, Aramandla R, Jenkins R, Stein R, Kaestner KH, Vahedi G, HPAP consortium, Brissova M, Powers AC
bioRxiv, 31 Aug 2020
Cited by: 0 articles | PPR: PPR208057
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Pancreatlas™: applying an adaptable framework to map the human pancreas in health and disease
Saunders DC, Messmer J, Kusmartseva I, Beery ML, Yang M, Atkinson MA, Powers AC, Cartailler J, Brissova M
bioRxiv, 28 Mar 2020
Cited by: 0 articles | PPR: PPR130119
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Decreased pancreatic acinar cell number in type 1 diabetes.
Wright JJ, Saunders DC, Dai C, Poffenberger G, Cairns B, Serreze DV, Harlan DM, Bottino R, Brissova M, Powers AC
Diabetologia, 63(7):1418-1423, 09 May 2020
Cited by: 36 articles | PMID: 32388592 | PMCID: PMC8403487
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