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Search life-sciences literature (45,104,145 articles, preprints and more)

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Cannabis Use and Cannabidiol Modulate HIV-Induced Alterations in TREM2 Expression: Implications for Age-Related Neuropathogenesis.
Avalos B, Kulbe JR, Ford MK, Laird AE, Walter K, Mante M, Florio JB, Boustani A, Chaillon A, Schlachetzki JCM, Sundermann EE, Volsky DJ, Rissman RA, Ellis RJ, Letendre SL, Iudicello J, Fields JA
Viruses, 16(10):1509, 24 Sep 2024
Cited by: 0 articles | PMID: 39459844 | PMCID: PMC11512329
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Dopamine-driven Increase in IL-1β in Myeloid Cells is Mediated by Differential Dopamine Receptor Expression and Exacerbated by HIV
Matt SM, Nolan R, Manikandan S, Agarwal Y, Channer B, Oteju O, Daniali M, Canagarajah JA, LuPone T, Mompho K, Runner K, Nickoloff-Bybel E, Li B, Niu M, Schlachetzki JCM, Fox HS, Gaskill PJ
bioRxiv, 10 Jun 2024
Cited by: 0 articles | PPR: PPR864739
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Cell-type-resolved mosaicism reveals clonal dynamics of the human forebrain.
Chung C, Yang X, Hevner RF, Kennedy K, Vong KI, Liu Y, Patel A, Nedunuri R, Barton ST, Noel G, Barrows C, Stanley V, Mittal S, Breuss MW, Schlachetzki JCM, Kingsmore SF, Gleeson JG
Nature, 629(8011):384-392, 10 Apr 2024
Cited by: 6 articles | PMID: 38600385 | PMCID: PMC11194162
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Distinct forebrain regions define a dichotomous astrocytic profile in multiple system atrophy.
Schneider Y, Gauer C, Andert M, Hoffmann A, Riemenschneider MJ, Krebs W, Chalmers N, Lötzsch C, Naumann UJ, Xiang W, Rothhammer V, Beckervordersandforth R, Schlachetzki JCM, Winkler J
Acta Neuropathol Commun, 12(1):1, 02 Jan 2024
Cited by: 1 article | PMID: 38167307 | PMCID: PMC10759635
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APOE4/4 is linked to damaging lipid droplets in Alzheimer's disease microglia.
Haney MS, Pálovics R, Munson CN, Long C, Johansson PK, Yip O, Dong W, Rawat E, West E, Schlachetzki JCM, Tsai A, Guldner IH, Lamichhane BS, Smith A, Schaum N, Calcuttawala K, Shin A, Wang YH, Wang C, [...] Wyss-Coray T
Nature, 628(8006):154-161, 13 Mar 2024
Cited by: 33 articles | PMID: 38480892 | PMCID: PMC10990924
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Genomic Mosaicism of the Brain: Origin, Impact, and Utility.
Graham JH, Schlachetzki JCM, Yang X, Breuss MW
Neurosci Bull, 40(6):759-776, 29 Oct 2023
Cited by: 1 article | PMID: 37898991 | PMCID: PMC11178748
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Publisher Correction: Mechanisms underlying HIV-associated cognitive impairment and emerging therapies for its management.
Ellis RJ, Marquine MJ, Kaul M, Fields JA, Schlachetzki JCM
Nat Rev Neurol, 19(12):787, 01 Dec 2023
Cited by: 1 article | PMID: 37872259
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Cell-type-resolved somatic mosaicism reveals clonal dynamics of the human forebrain
Chung C, Yang X, Hevner RF, Kennedy K, Vong KI, Liu Y, Patel A, Nedunuri R, Barton ST, Barrows C, Stanley V, Mittal S, Breuss MW, Schlachetzki JCM, Gleeson JG
bioRxiv, 25 Oct 2023
Cited by: 0 articles | PPR: PPR747479
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Human microglia maturation is underpinned by specific gene regulatory networks.
Han CZ, Li RZ, Hansen E, Trescott S, Fixsen BR, Nguyen CT, Mora CM, Spann NJ, Bennett HR, Poirion O, Buchanan J, Warden AS, Xia B, Schlachetzki JCM, Pasillas MP, Preissl S, Wang A, O'Connor C, Shriram S, [...] Coufal NG
Immunity, 56(9):2152-2171.e13, 14 Aug 2023
Cited by: 9 articles | PMID: 37582369 | PMCID: PMC10529991
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Immune mechanisms of depression in rheumatoid arthritis.
Brock J, Basu N, Schlachetzki JCM, Schett G, McInnes IB, Cavanagh J
Nat Rev Rheumatol, 19(12):790-804, 03 Nov 2023
Cited by: 10 articles | PMID: 37923863
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RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression.
Abe Y, Kofman ER, Almeida M, Ouyang Z, Ponte F, Mueller JR, Cruz-Becerra G, Sakai M, Prohaska TA, Spann NJ, Resende-Coelho A, Seidman JS, Stender JD, Taylor H, Fan W, Link VM, Cobo I, Schlachetzki JCM, Hamakubo T, [...] Glass CK
Mol Cell, 83(19):3421-3437.e11, 25 Sep 2023
Cited by: 4 articles | PMID: 37751740 | PMCID: PMC10591845
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Correction: A prebiotic diet modulates microglial states and motor deficits in α-synuclein overexpressing mice.
Abdel-Haq R, Schlachetzki JCM, Boktor JC, Cantu-Jungles TM, Thron T, Zhang M, Bostick JW, Khazaei T, Chilakala S, Morais LH, Humphrey G, Keshavarzian A, Katz JE, Thomson M, Knight R, Gradinaru V, Hamaker BR, Glass CK, Mazmanian SK
Elife, 12:e92367, 31 Aug 2023
Cited by: 0 articles | PMID: 37650862 | PMCID: PMC10471158
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Mechanisms underlying HIV-associated cognitive impairment and emerging therapies for its management.
Ellis RJ, Marquine MJ, Kaul M, Fields JA, Schlachetzki JCM
Nat Rev Neurol, 19(11):668-687, 10 Oct 2023
Cited by: 7 articles | PMID: 37816937
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An in vivo neuroimmune organoid model to study human microglia phenotypes.
Schafer ST, Mansour AA, Schlachetzki JCM, Pena M, Ghassemzadeh S, Mitchell L, Mar A, Quang D, Stumpf S, Ortiz IS, Lana AJ, Baek C, Zaghal R, Glass CK, Nimmerjahn A, Gage FH
Cell, 186(10):2111-2126.e20, 01 May 2023
Cited by: 49 articles | PMID: 37172564 | PMCID: PMC10284271
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Microglial pattern recognition via IL-33 promotes synaptic refinement in developing corticothalamic circuits in mice.
Han RT, Vainchtein ID, Schlachetzki JCM, Cho FS, Dorman LC, Ahn E, Kim DK, Barron JJ, Nakao-Inoue H, Molofsky AB, Glass CK, Paz JT, Molofsky AV
J Exp Med, 220(2):e20220605, 15 Dec 2022
Cited by: 12 articles | PMID: 36520518 | PMCID: PMC9757845
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Human microglia phenotypes in the brain associated with HIV infection.
Schlachetzki JCM, Zhou Y, Glass CK
Curr Opin Neurobiol, 77:102637, 01 Oct 2022
Cited by: 5 articles | PMID: 36194988
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TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4.
Gratuze M, Schlachetzki JCM, D'Oliveira Albanus R, Jain N, Novotny B, Brase L, Rodriguez L, Mansel C, Kipnis M, O'Brien S, Pasillas MP, Lee C, Manis M, Colonna M, Harari O, Glass CK, Ulrich JD, Holtzman DM
Neuron, 111(2):202-219.e7, 10 Nov 2022
Cited by: 30 articles | PMID: 36368315 | PMCID: PMC9852006
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Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood.
Ge YJ, Ou YN, Deng YT, Wu BS, Yang L, Zhang YR, Chen SD, Huang YY, Dong Q, Tan L, Yu JT, International FTD-Genomics Consortium
Biol Psychiatry, 93(9):770-779, 09 Nov 2022
Cited by: 10 articles | PMID: 36759259
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A prebiotic diet modulates microglial states and motor deficits in α-synuclein overexpressing mice.
Abdel-Haq R, Schlachetzki JCM, Boktor JC, Cantu-Jungles TM, Thron T, Zhang M, Bostick JW, Khazaei T, Chilakala S, Morais LH, Humphrey G, Keshavarzian A, Katz JE, Thomson M, Knight R, Gradinaru V, Hamaker BR, Glass CK, Mazmanian SK
Elife, 11:e81453, 08 Nov 2022
Cited by: 22 articles | PMID: 36346385 | PMCID: PMC9668333
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Increased post-mitotic senescence in aged human neurons is a pathological feature of Alzheimer's disease.
Herdy JR, Traxler L, Agarwal RK, Karbacher L, Schlachetzki JCM, Boehnke L, Zangwill D, Galasko D, Glass CK, Mertens J, Gage FH
Cell Stem Cell, 29(12):1637-1652.e6, 01 Dec 2022
Cited by: 45 articles | PMID: 36459967 | PMCID: PMC10093780
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CSF1R-Mediated Myeloid Cell Depletion Prolongs Lifespan But Aggravates Distinct Motor Symptoms in a Model of Multiple System Atrophy.
Battis K, Florio JB, Mante M, Lana A, Naumann I, Gauer C, Lambrecht V, Müller SJ, Cobo I, Fixsen B, Kim HY, Masliah E, Glass CK, Schlachetzki JCM, Rissman RA, Winkler J, Hoffmann A
J Neurosci, 42(40):7673-7688, 06 Sep 2022
Cited by: 4 articles | PMID: 36333098 | PMCID: PMC9546481
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Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer's disease.
Traxler L, Herdy JR, Stefanoni D, Eichhorner S, Pelucchi S, Szücs A, Santagostino A, Kim Y, Agarwal RK, Schlachetzki JCM, Glass CK, Lagerwall J, Galasko D, Gage FH, D'Alessandro A, Mertens J
Cell Metab, 34(9):1248-1263.e6, 19 Aug 2022
Cited by: 50 articles | PMID: 35987203 | PMCID: PMC9458870
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Somatic mosaicism reveals clonal distributions of neocortical development.
Breuss MW, Yang X, Schlachetzki JCM, Antaki D, Lana AJ, Xu X, Chung C, Chai G, Stanley V, Song Q, Newmeyer TF, Nguyen A, O'Brien S, Hoeksema MA, Cao B, Nott A, McEvoy-Venneri J, Pasillas MP, Barton ST, [...] Gleeson JG
Nature, 604(7907):689-696, 20 Apr 2022
Cited by: 28 articles | PMID: 35444276 | PMCID: PMC9436791
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Chronic peripheral inflammation: a possible contributor to neurodegenerative diseases.
Süβ P, Lana AJ, Schlachetzki JCM
Neural Regen Res, 16(9):1711-1714, 01 Sep 2021
Cited by: 26 articles | PMID: 33510059 | PMCID: PMC8328777
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Interleukin-33 coordinates a microglial phagocytic response and limits corticothalamic excitability and seizure susceptibility
Han RT, Vainchtein ID, Schlachetzki JCM, Cho FS, Dorman LC, Johung T, Ahn E, Barron JT, Nakao-Inoue H, Joshi A, Molofsky AB, Glass CK, Paz JT, Molofsky AV
bioRxiv, 06 Aug 2021
Cited by: 0 articles | PPR: PPR380042
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