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Search life-sciences literature (45,103,589 articles, preprints and more)

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Correlation of safety and efficacy of atezolizumab therapy across indications.
Durán-Pacheco G, Chandler GS, Maiya V, Socinski MA, Sonpavde G, Puente J, Essioux L, Carter C, Cardona JV, Mohindra R, Naidoo J
J Immunother Cancer, 12(11):e010158, 12 Nov 2024
Cited by: 0 articles | PMID: 39537212
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A phase I study to evaluate the safety, pharmacokinetics, and pharmacodynamics of PF-06939999 (PRMT5 inhibitor) in patients with selected advanced or metastatic tumors with high incidence of splicing factor gene mutations.
Rodon J, Rodriguez E, Maitland ML, Tsai FY, Socinski MA, Berlin JD, Thomas JS, Al Baghdadi T, Wang IM, Guo C, Golmakani M, Clark LN, Gazdoiu M, Li M, Tolcher AW
ESMO Open, 9(4):102961, 18 Apr 2024
Cited by: 2 articles | PMID: 38640748 | PMCID: PMC11047177
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A lack of association between BMI and chemoimmunotherapy efficacy in advanced non-small cell lung cancer: Secondary analysis of the IMpower150 and IMpower130 clinical trials.
Li LX, Socinski MA, Kichenadasse G, Karapetis CS, Shahnam A, McKinnon RA, Rowland A, Hopkins AM, Sorich MJ
BMC Cancer, 24(1):379, 25 Mar 2024
Cited by: 0 articles | PMID: 38528478 | PMCID: PMC10964615
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Combined use of CYFRA 21-1 and CA 125 predicts survival of patients with metastatic NSCLC and stable disease in IMpower150.
Mang A, Zou W, Rolny V, Reck M, Cigoianu D, Schulze K, Holdenrieder S, Socinski MA, Shames DS, Wehnl B, Patil NS
Tumour Biol, 46(s1):S177-S190, 01 Jan 2024
Cited by: 0 articles | PMID: 37545290
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A phase II clinical trial evaluating the safety and efficacy of durvalumab as first line therapy in advanced and metastatic non-small cell lung cancer patients with Eastern Cooperative Oncology Group performance status of 2.
Shaverdashvili K, Reyes V, Wang H, Mehta D, Marsh C, Waas JK, VanderWeele RA, Peracha SM, Liang H, Socinski MA, Gerber DE, Dowell JE, Villaruz LC
EClinicalMedicine, 66:102317, 21 Nov 2023
Cited by: 1 article | PMID: 38192592 | PMCID: PMC10772260
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Circulating Tumor DNA Monitoring on Chemo-immunotherapy for Risk Stratification in Advanced Non-Small Cell Lung Cancer.
Pellini B, Madison RW, Childress MA, Miller ST, Gjoerup O, Cheng J, Huang RSP, Krainock M, Gupta P, Zou W, Shames DS, Moshkevich S, Ballinger M, Liu MC, Young A, Srivastava MK, Oxnard GR, Socinski MA
Clin Cancer Res, 29(22):4596-4605, 01 Nov 2023
Cited by: 7 articles | PMID: 37702716 | PMCID: PMC10643998
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Correction: Tumor Dynamic Model-Based Decision Support for Phase Ib/II Combination Studies: A Retrospective Assessment Based on Resampling of the Phase III Study IMpower150.
Bruno R, Marchand M, Yoshida K, Chan P, Li H, Zou W, Mercier F, Chanu P, Wu B, Lee A, Li C, Jin JY, Maitland ML, Reck M, Socinski MA
Clin Cancer Res, 29(20):4314, 01 Oct 2023
Cited by: 0 articles | PMID: 37828897
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Population Pharmacokinetics of MYL-1402O, a Proposed Biosimilar to Bevacizumab and Reference Product (Avastin^®) in Patients with Non-squamous Non-small Cell Lung Cancer.
Owen JS, Rackley RJ, Hummel MA, Roepcke S, Huang H, Liu M, Idris TA, Murugesan SMN, Marwah A, Loganathan S, Ranganna G, Barve A, Waller CF, Socinski MA
Eur J Drug Metab Pharmacokinet, 48(6):675-689, 04 Oct 2023
Cited by: 2 articles | PMID: 37792130
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Impact of gender and mutational differences in hormone receptor expressing non-small cell lung cancer.
Hsu R, Chen D, Xia B, Feldman R, Cozen W, Raez LE, Borghaei H, Kim C, Nagasaka M, Mamdani H, Vanderwalde AM, Lopes G, Socinski MA, Wozniak AJ, Spira AI, Liu SV, Nieva JJ
Front Oncol, 13:1215524, 28 Aug 2023
Cited by: 0 articles | PMID: 37700839 | PMCID: PMC10494442
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Emerging agents for the treatment of advanced or metastatic NSCLC without actionable genomic alterations with progression on first-line therapy.
Leal T, Socinski MA
Expert Rev Anticancer Ther, 23(8):817-833, 24 Jul 2023
Cited by: 0 articles | PMID: 37486248
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Pan-tumor survey of RET fusions as detected by next-generation RNA sequencing identified RET fusion positive colorectal carcinoma as a unique molecular subset.
Nagasaka M, Brazel D, Baca Y, Xiu J, Al-Hallak MN, Kim C, Nieva J, Swensen JJ, Spetzler D, Korn WM, Socinski MA, Raez LE, Halmos B, Ou SI
Transl Oncol, 36:101744, 27 Jul 2023
Cited by: 5 articles | PMID: 37516008 | PMCID: PMC10410168
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Safety, Tolerability, and Antitumor Activity of Zipalertinib Among Patients With Non-Small-Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Exon 20 Insertions.
Piotrowska Z, Tan DS, Smit EF, Spira AI, Soo RA, Nguyen D, Lee VH, Yang JC, Velcheti V, Wrangle JM, Socinski MA, Koczywas M, Janik JE, Jones J, Yu HA
J Clin Oncol, 41(26):4218-4225, 29 Jun 2023
Cited by: 10 articles | PMID: 37384848
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Phase II Randomized Trial of Carboplatin, Pemetrexed, and Bevacizumab With and Without Atezolizumab in Stage IV Nonsquamous Non-Small-Cell Lung Cancer Patients Who Harbor a Sensitizing EGFR Mutation or Have Never Smoked.
Bodor JN, Patel JD, Wakelee HA, Levy BP, Borghaei H, Pellini B, Costello MR, Dowell JE, Finley G, Huang CH, Neal JW, Nieva JJ, Puri S, Socinski MA, Thomas C, Ross EA, Litwin S, Clapper ML, Treat J
Clin Lung Cancer, 24(7):e242-e246, 11 May 2023
Cited by: 1 article | PMID: 37451930 | PMCID: PMC11476834
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Low Risk of Hyperprogression with First-Line Chemoimmunotherapy for Advanced Non-Small Cell Lung Cancer: Pooled Analysis of 7 Clinical Trials.
Li LX, Cappuzzo F, Matos I, Socinski MA, Hopkins AM, Sorich MJ
Oncologist, 28(4):e205-e211, 01 Apr 2023
Cited by: 5 articles | PMID: 36905578 | PMCID: PMC10078909
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Association of Immune-Related Adverse Events With Efficacy of Atezolizumab in Patients With Non-Small Cell Lung Cancer: Pooled Analyses of the Phase 3 IMpower130, IMpower132, and IMpower150 Randomized Clinical Trials.
Socinski MA, Jotte RM, Cappuzzo F, Nishio M, Mok TSK, Reck M, Finley GG, Kaul MD, Yu W, Paranthaman N, Bara I, West HJ
JAMA Oncol, 9(4):527-535, 01 Apr 2023
Cited by: 67 articles | PMID: 36795388 | PMCID: PMC9936386
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Poziotinib in Treatment-Naive NSCLC Harboring HER2 Exon 20 Mutations: ZENITH20-4, A Multicenter, Multicohort, Open-Label, Phase 2 Trial (Cohort 4).
Cornelissen R, Prelaj A, Sun S, Baik C, Wollner M, Haura EB, Mamdani H, Riess JW, Cappuzzo F, Garassino MC, Heymach JV, Socinski MA, Leu SY, Bhat G, Lebel F, Le X, ZENITH20-4 Investigators
J Thorac Oncol, 18(8):1031-1041, 21 Mar 2023
Cited by: 16 articles | PMID: 36958688
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A longitudinal circulating tumor DNA-based model associated with survival in metastatic non-small-cell lung cancer.
Assaf ZJF, Zou W, Fine AD, Socinski MA, Young A, Lipson D, Freidin JF, Kennedy M, Polisecki E, Nishio M, Fabrizio D, Oxnard GR, Cummings C, Rode A, Reck M, Patil NS, Lee M, Shames DS, Schulze K
Nat Med, 29(4):859-868, 16 Mar 2023
Cited by: 26 articles | PMID: 36928816 | PMCID: PMC10115641
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Guidance for clinicians and patients with non-small cell lung cancer in the time of precision medicine.
Villaruz LC, Socinski MA, Weiss J
Front Oncol, 13:1124167, 01 Feb 2023
Cited by: 8 articles | PMID: 37077826 | PMCID: PMC10107372
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Tumor Dynamic Model-Based Decision Support for Phase Ib/II Combination Studies: A Retrospective Assessment Based on Resampling of the Phase III Study IMpower150.
Bruno R, Marchand M, Yoshida K, Chan P, Li H, Zou W, Mercier F, Chanu P, Wu B, Lee A, Li C, Jin JY, Maitland ML, Reck M, Socinski MA
Clin Cancer Res, 29(6):1047-1055, 01 Mar 2023
Cited by: 4 articles | PMID: 36595566 | PMCID: PMC10023325
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GEMSTONE-302: "If you keep doing the same thing you get the same result".
Guo M, Liu J, Mekhail T, Socinski MA
Chin Clin Oncol, 11(6):48, 15 Nov 2022
Cited by: 0 articles | PMID: 36408544
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A Single Center Retrospective Study of the Impact of COVID-19 Infection on Immune-related Adverse Events in Cancer Patients Receiving Immune Checkpoint Inhibitors.
Guo M, Liu J, Miao R, Ahmed Z, Yu J, Guan J, Ahmad S, Zhou S, Grove A, Manoucheri M, Socinski MA, Mekhail T
J Immunother, 45(9):389-395, 05 Sep 2022
Cited by: 6 articles | PMID: 36066505 | PMCID: PMC9528807
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COVID-19 Outcomes in Stage IV Cancer Patients Receiving Immune Checkpoint Inhibitors.
Guo M, Liu J, Zhou S, Yu J, Ahmed Z, Ahmad S, Manoucheri M, Socinski MA, Mekhail T, Hsu V
SN Compr Clin Med, 4(1):193, 26 Aug 2022
Cited by: 0 articles | PMID: 36043120 | PMCID: PMC9411835
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The Applicability of the Results in the Asian Population of ORIENT-11 to a Western Population According to the ICH-E5 Framework.
Liu SV, Nagasaka M, Stefaniak V, Gruver K, Lin Y, Ferry D, Socinski MA, Zhang L
Front Oncol, 12:859892, 10 Jun 2022
Cited by: 0 articles | PMID: 35756655 | PMCID: PMC9226396
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A phase 1b/2 study of PF-06747775 as monotherapy or in combination with Palbociclib in patients with epidermal growth factor receptor mutant advanced non-small cell lung cancer.
Cho BC, Goldberg SB, Kim DW, Socinski MA, Burns TF, Lwin Z, Pathan N, Ma WD, Masters JC, Cossons N, Wilner K, Nishio M, Husain H
Expert Opin Investig Drugs, 31(7):747-757, 03 Jun 2022
Cited by: 5 articles | PMID: 35657653
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Blood-based tumor mutational burden as a biomarker for atezolizumab in non-small cell lung cancer: the phase 2 B-F1RST trial.
Kim ES, Velcheti V, Mekhail T, Yun C, Shagan SM, Hu S, Chae YK, Leal TA, Dowell JE, Tsai ML, Dakhil CSR, Stella P, Jin Y, Shames DS, Schleifman E, Fabrizio DA, Phan S, Socinski MA
Nat Med, 28(5):939-945, 14 Apr 2022
Cited by: 68 articles | PMID: 35422531 | PMCID: PMC9117143
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