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High PEEP/low FiO<sub>2</sub> ventilation is associated with lower mortality in COVID-19.
Goossen RL, van Vliet R, Bos LDJ, Buiteman-Kruizinga LA, Hollman MW, Myatra SN, Neto AS, Spronk PE, van der Woude MCE, van Meenen DMP, Paulus F, Schultz MJ, PRoVAcT-COVID investigators
J Crit Care, 83:154854, 11 Jul 2024
Cited by: 0 articles | PMID: 38996499
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Thermodynamic profiles for cotranslational trigger factor substrate recognition.
Herling TW, Cassaignau AME, Wentink AS, Peter QAE, Kumar PC, Kartanas T, Schneider MM, Cabrita LD, Christodoulou J, Knowles TPJ
Sci Adv, 10(28):eadn4824, 10 Jul 2024
Cited by: 0 articles | PMID: 38985872 | PMCID: PMC11235164
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A unique chaperoning mechanism in class A JDPs recognizes and stabilizes mutant p53.
Zoltsman G, Dang TL, Kuchersky M, Faust O, Silva MS, Ilani T, Wentink AS, Bukau B, Rosenzweig R
Mol Cell, 84(8):1512-1526.e9, 19 Mar 2024
Cited by: 1 article | PMID: 38508184
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Effect of a Standardized Family Participation Program in the ICU: A Multicenter Stepped-Wedge Cluster Randomized Controlled Trial.
Dijkstra BM, Rood PJT, Teerenstra S, Rutten AMF, Leerentveld C, Burgers-Bonthuis DC, Festen-Spanjer B, Klarenbeek T, Van Den Boogaard M, Ewalds E, Schoonhoven L, Van Der Hoeven JG, Vloet LCM, from the EFfect of FAMily PARTicipation in essential care (EFFAMPART) Study Group
Crit Care Med, 52(3):420-431, 07 Nov 2023
Cited by: 0 articles | PMID: 37934138 | PMCID: PMC10876177
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Protein disaggregation machineries in the human cytosol.
Wentink A, Rosenzweig R
Curr Opin Struct Biol, 83:102735, 23 Nov 2023
Cited by: 2 articles | PMID: 38000128
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A unique chaperoning mechanism in Class A JDPs recognizes and stabilizes mutant p53
Zoltsman G, Dang TL, Kuchersky M, Faust O, Silva MS, Ilani T, Wentink AS, Bukau B, Rosenzweig R
bioRxiv, 28 Nov 2023
Cited by: 0 articles | PPR: PPR765814
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Thermodynamic profiles for co-translational trigger factor function
Herling TW, Cassaignau AME, Wentink AS, Peter QAE, Kumar PC, Kartanas T, Schneider MM, Cabrita LD, Christodoulou J, Knowles TPJ
bioRxiv, 24 Aug 2023
Cited by: 0 articles | PPR: PPR704321
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Cooperative amyloid fibre binding and disassembly by the Hsp70 disaggregase.
Beton JG, Monistrol J, Wentink A, Johnston EC, Roberts AJ, Bukau BG, Hoogenboom BW, Saibil HR
EMBO J, 41(16):e110410, 13 Jun 2022
Cited by: 8 articles | PMID: 35698800 | PMCID: PMC9379549
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Cooperative Amyloid Fibre Binding and Disassembly by the Hsp70 disaggregase
Beton JG, Monistrol J, Wentink A, Johnston E, Roberts A, Bukau B, Hoogenboom B, Saibil H
bioRxiv, 30 Aug 2021
Cited by: 0 articles | PPR: PPR388489
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Author Correction: Molecular dissection of amyloid disaggregation by human HSP70.
Wentink AS, Nillegoda NB, Feufel J, Ubartaitė G, Schneider CP, De Los Rios P, Hennig J, Barducci A, Bukau B
Nature, 589(7841):E2, 01 Jan 2021
Cited by: 1 article | PMID: 33353983
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HSP40 proteins use class-specific regulation to drive HSP70 functional diversity.
Faust O, Abayev-Avraham M, Wentink AS, Maurer M, Nillegoda NB, London N, Bukau B, Rosenzweig R
Nature, 587(7834):489-494, 11 Nov 2020
Cited by: 81 articles | PMID: 33177718
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Molecular dissection of amyloid disaggregation by human HSP70.
Wentink AS, Nillegoda NB, Feufel J, Ubartaitė G, Schneider CP, De Los Rios P, Hennig J, Barducci A, Bukau B
Nature, 587(7834):483-488, 11 Nov 2020
Cited by: 86 articles | PMID: 33177717
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Disassembly of Tau fibrils by the human Hsp70 disaggregation machinery generates small seeding-competent species.
Nachman E, Wentink AS, Madiona K, Bousset L, Katsinelos T, Allinson K, Kampinga H, McEwan WA, Jahn TR, Melki R, Mogk A, Bukau B, Nussbaum-Krammer C
J Biol Chem, 295(28):9676-9690, 28 May 2020
Cited by: 67 articles | PMID: 32467226 | PMCID: PMC7363153
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Functional diversity between HSP70 paralogs caused by variable interactions with specific co-chaperones.
Serlidaki D, van Waarde MAWH, Rohland L, Wentink AS, Dekker SL, Kamphuis MJ, Boertien JM, Brunsting JF, Nillegoda NB, Bukau B, Mayer MP, Kampinga HH, Bergink S
J Biol Chem, 295(21):7301-7316, 13 Apr 2020
Cited by: 27 articles | PMID: 32284329 | PMCID: PMC7247296
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Protein Quality Control Pathways at the Crossroad of Synucleinopathies.
De Mattos EP, Wentink A, Nussbaum-Krammer C, Hansen C, Bergink S, Melki R, Kampinga HH
J Parkinsons Dis, 10(2):369-382, 01 Jan 2020
Cited by: 16 articles | PMID: 31985474 | PMCID: PMC7242842
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Disassembly of Tau fibrils by the human Hsp70 disaggregation machinery generates small seeding-competent species
Nachman E, Wentink A, Madiona K, Bousset L, Katsinelos T, Kampinga H, McEwan WA, Jahn TR, Melki R, Mogk A, Bukau B, Nussbaum-Krammer C
bioRxiv, 16 Dec 2019
Cited by: 0 articles | PPR: PPR105850
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Modulation of Amyloid States by Molecular Chaperones.
Wentink A, Nussbaum-Krammer C, Bukau B
Cold Spring Harb Perspect Biol, 11(7):a033969, 01 Jul 2019
Cited by: 42 articles | PMID: 30755450 | PMCID: PMC6601462
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Systematic mapping of free energy landscapes of a growing filamin domain during biosynthesis.
Waudby CA, Wlodarski T, Karyadi ME, Cassaignau AME, Chan SHS, Wentink AS, Schmidt-Engler JM, Camilloni C, Vendruscolo M, Cabrita LD, Christodoulou J
Proc Natl Acad Sci U S A, 115(39):9744-9749, 10 Sep 2018
Cited by: 24 articles | PMID: 30201720 | PMCID: PMC6166796
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Protein Disaggregation in Multicellular Organisms.
Nillegoda NB, Wentink AS, Bukau B
Trends Biochem Sci, 43(4):285-300, 28 Feb 2018
Cited by: 62 articles | PMID: 29501325
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Systematic mapping of the free energy landscapes of a growing immunoglobulin domain identifies a kinetic intermediate associated with co-translational proline isomerization
Waudby CA, Karyadi M, Wlodarski T, Cassaignau AME, Chan S, Schmidt-Engler JM, Wentink AS, Camilloni C, Vendruscolo M, Cabrita LD, Christodoulou J
bioRxiv, 14 Sep 2017
Cited by: 0 articles | PPR: PPR25188
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Alternative modes of client binding enable functional plasticity of Hsp70.
Mashaghi A, Bezrukavnikov S, Minde DP, Wentink AS, Kityk R, Zachmann-Brand B, Mayer MP, Kramer G, Bukau B, Tans SJ
Nature, 539(7629):448-451, 26 Oct 2016
Cited by: 96 articles | PMID: 27783598
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Structural characterization of the interaction of α-synuclein nascent chains with the ribosomal surface and trigger factor.
Deckert A, Waudby CA, Wlodarski T, Wentink AS, Wang X, Kirkpatrick JP, Paton JF, Camilloni C, Kukic P, Dobson CM, Vendruscolo M, Cabrita LD, Christodoulou J
Proc Natl Acad Sci U S A, 113(18):5012-5017, 18 Apr 2016
Cited by: 29 articles | PMID: 27092002 | PMCID: PMC4983817
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A structural ensemble of a ribosome-nascent chain complex during cotranslational protein folding.
Cabrita LD, Cassaignau AME, Launay HMM, Waudby CA, Wlodarski T, Camilloni C, Karyadi ME, Robertson AL, Wang X, Wentink AS, Goodsell L, Woolhead CA, Vendruscolo M, Dobson CM, Christodoulou J
Nat Struct Mol Biol, 23(4):278-285, 29 Feb 2016
Cited by: 85 articles | PMID: 26926436 | PMCID: PMC5405865
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Structure and dynamics of the E. coli chaperone, trigger factor, and its interaction with ribosome-nascent chain complexes
Wentink AS
University College London (University of London), 01 Jan 2015
Cited by: 0 articles | ETH: 654683
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