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Suggested authors matching "AUTH:Wiede F" with an ORCID

Florian Wiede
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Correction to: Pancreatic T cell protein-tyrosine phosphatase deficiency affects beta cell function in mice.
Xi Y, Liu S, Bettaieb A, Matsuo K, Matsuo I, Hosein E, Chahed S, Wiede F, Zhang S, Zhang ZY, Kulkarni RN, Tiganis T, Haj FG
Diabetologia, 67(1):215, 01 Jan 2024
Cited by: 0 articles | PMID: 37861718
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Mitochondria- and NOX4-dependent antioxidant defense mitigates progression to nonalcoholic steatohepatitis in obesity.
Greatorex S, Kaur S, Xirouchaki CE, Goh PK, Wiede F, Genders AJ, Tran M, Jia Y, Raajendiran A, Brown WA, McLean CA, Sadoshima J, Watt MJ, Tiganis T
J Clin Invest, 134(3):e162533, 07 Dec 2023
Cited by: 4 articles | PMID: 38060313 | PMCID: PMC10849767
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T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice.
Wiede F, Shields BJ, Kyparissoudis SHCK, van Vliet C, Galic S, Tremblay ML, Russell SM, Godfrey DI, Tiganis T
J Clin Invest, 133(20):e175163, 16 Oct 2023
Cited by: 0 articles | PMID: 37843283 | PMCID: PMC10575716
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A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity.
Liang S, Tran E, Du X, Dong J, Sudholz H, Chen H, Qu Z, Huntington ND, Babon JJ, Kershaw NJ, Zhang ZY, Baell JB, Wiede F, Tiganis T
Nat Commun, 14(1):4524, 27 Jul 2023
Cited by: 20 articles | PMID: 37500611 | PMCID: PMC10374545
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A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity
Liang S, Tran E, Du X, Dong J, Sudholz H, Chen H, Qu Z, Huntington ND, Babon JJ, Kershaw NJ, Zhang Z, Baell JB, Wiede F, Tiganis T
bioRxiv, 16 Jun 2023
Cited by: 0 articles | PPR: PPR677023
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Small Molecule Degraders of Protein Tyrosine Phosphatase 1B and T-Cell Protein Tyrosine Phosphatase for Cancer Immunotherapy.
Dong J, Miao J, Miao Y, Qu Z, Zhang S, Zhu P, Wiede F, Jassim BA, Bai Y, Nguyen Q, Lin J, Chen L, Tiganis T, Tao WA, Zhang ZY
Angew Chem Int Ed Engl, 62(22):e202303818, 21 Apr 2023
Cited by: 10 articles | PMID: 36973833 | PMCID: PMC10196813
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Elevated Hypothalamic TCPTP in Obesity Contributes to Cellular Leptin Resistance.
Loh K, Fukushima A, Zhang X, Galic S, Briggs D, Enriori PJ, Simonds S, Wiede F, Reichenbach A, Hauser C, Sims NA, Bence KK, Zhang S, Zhang ZY, Kahn BB, Neel BG, Andrews ZB, Cowley MA, Tiganis T
Cell Metab, 34(11):1892, 01 Nov 2022
Cited by: 3 articles | PMID: 36323237 | PMCID: PMC9719734
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Stepwise progression of β-selection during T cell development involves histone deacetylation.
Chann AS, Charnley M, Newton LM, Newbold A, Wiede F, Tiganis T, Humbert PO, Johnstone RW, Russell SM
Life Sci Alliance, 6(1):e202201645, 25 Oct 2022
Cited by: 0 articles | PMID: 36283704 | PMCID: PMC9595210
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Targeting Protein Tyrosine Phosphatase 22 Does Not Enhance the Efficacy of Chimeric Antigen Receptor T Cells in Solid Tumors.
Du X, Darcy PK, Wiede F, Tiganis T
Mol Cell Biol, 42(3):e0044921, 18 Jan 2022
Cited by: 9 articles | PMID: 35041491 | PMCID: PMC8929386
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PTP1B Is an Intracellular Checkpoint that Limits T-cell and CAR T-cell Antitumor Immunity.
Wiede F, Lu KH, Du X, Zeissig MN, Xu R, Goh PK, Xirouchaki CE, Hogarth SJ, Greatorex S, Sek K, Daly RJ, Beavis PA, Darcy PK, Tonks NK, Tiganis T
Cancer Discov, 12(3):752-773, 01 Mar 2022
Cited by: 57 articles | PMID: 34794959 | PMCID: PMC8904293
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Stepwise progression of β-selection during T cell development as revealed by histone deacetylation inhibition
Chann AS, Charnley M, Newton LM, Newbold A, Wiede F, Wiede F, Tiganis T, Humbert PO, Johnstone RW, Russell SM
bioRxiv, 04 Oct 2021
Cited by: 0 articles | PPR: PPR403804
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PTPN2 elicits cell autonomous and non-cell autonomous effects on antitumor immunity in triple-negative breast cancer.
Goh PK, Wiede F, Zeissig MN, Britt KL, Liang S, Molloy T, Goode N, Xu R, Loi S, Muller M, Humbert PO, McLean C, Tiganis T
Sci Adv, 8(8):eabk3338, 23 Feb 2022
Cited by: 15 articles | PMID: 35196085 | PMCID: PMC8865802
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PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity
Wiede F, Lu K, Du X, Zeissig MN, Xu R, Goh PK, Xirouchaki CE, Hogarth SJ, Greatorex S, Sek K, Daly RJ, Beavis PA, Darcy PK, Tonks NK, Tiganis T
bioRxiv, 12 Nov 2021
Cited by: 0 articles | PPR: PPR419359
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Ptpn2 and KLRG1 regulate the generation and function of tissue-resident memory CD8+ T cells in skin.
Hochheiser K, Wiede F, Wagner T, Freestone D, Enders MH, Olshansky M, Russ B, Nüssing S, Bawden E, Braun A, Bachem A, Gressier E, McConville R, Park SL, Jones CM, Davey GM, Gyorki DE, Tscharke D, Parish IA, [...] Gebhardt T
J Exp Med, 218(6):e20200940, 01 Jun 2021
Cited by: 12 articles | PMID: 33914023 | PMCID: PMC8091133
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PTPN2 Deficiency Enhances Programmed T Cell Expansion and Survival Capacity of Activated T Cells.
Flosbach M, Oberle SG, Scherer S, Zecha J, von Hoesslin M, Wiede F, Chennupati V, Cullen JG, List M, Pauling JK, Baumbach J, Kuster B, Tiganis T, Zehn D
Cell Rep, 32(4):107957, 01 Jul 2020
Cited by: 25 articles | PMID: 32726622 | PMCID: PMC7408006
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A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1.
Le Nours J, Gherardin NA, Ramarathinam SH, Awad W, Wiede F, Gully BS, Khandokar Y, Praveena T, Wubben JM, Sandow JJ, Webb AI, von Borstel A, Rice MT, Redmond SJ, Seneviratna R, Sandoval-Romero ML, Li S, Souter MNT, Eckle SBG, [...] Rossjohn J
Science, 366(6472):1522-1527, 01 Dec 2019
Cited by: 76 articles | PMID: 31857486
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PTPN2 phosphatase deletion in T cells promotes anti-tumour immunity and CAR T-cell efficacy in solid tumours.
Wiede F, Lu KH, Du X, Liang S, Hochheiser K, Dodd GT, Goh PK, Kearney C, Meyran D, Beavis PA, Henderson MA, Park SL, Waithman J, Zhang S, Zhang ZY, Oliaro J, Gebhardt T, Darcy PK, Tiganis T
EMBO J, 39(2):e103637, 05 Dec 2019
Cited by: 70 articles | PMID: 31803974 | PMCID: PMC6960448
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PTPN2 deletion in T cells promotes anti-tumour immunity and CAR T cell efficacy in solid tumours
Wiede F, Lu K, Du X, Liang S, Hochheiser K, Dodd GT, Goh P, Kearney C, Meyran D, Beavis PA, Henderson MA, Park SL, Waithman J, Zhang S, Zhang Z, Oliaro J, Gebhardt T, Darcy PK, Tiganis T
bioRxiv, 05 Sep 2019
Cited by: 0 articles | PPR: PPR91171
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Activation of naïve CD4⁺ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4⁺ T cells.
Twohig JP, Cardus Figueras A, Andrews R, Wiede F, Cossins BC, Derrac Soria A, Lewis MJ, Townsend MJ, Millrine D, Li J, Hill DG, Uceda Fernandez J, Liu X, Szomolay B, Pepper CJ, Taylor PR, Pitzalis C, Tiganis T, Williams NM, [...] Jones SA
Nat Immunol, 20(4):458-470, 19 Mar 2019
Cited by: 21 articles | PMID: 30890796 | PMCID: PMC7610646
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Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC.
Grohmann M, Wiede F, Dodd GT, Gurzov EN, Ooi GJ, Butt T, Rasmiena AA, Kaur S, Gulati T, Goh PK, Treloar AE, Archer S, Brown WA, Muller M, Watt MJ, Ohara O, McLean CA, Tiganis T
Cell, 175(5):1289-1306.e20, 25 Oct 2018
Cited by: 201 articles | PMID: 30454647 | PMCID: PMC6242467
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T-Cell-Specific PTPN2 Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Comorbidities.
Wiede F, Brodnicki TC, Goh PK, Leong YA, Jones GW, Yu D, Baxter AG, Jones SA, Kay TWH, Tiganis T
Diabetes, 68(6):1251-1266, 01 Apr 2019
Cited by: 25 articles | PMID: 30936146
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Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity.
Svensson MN, Doody KM, Schmiedel BJ, Bhattacharyya S, Panwar B, Wiede F, Yang S, Santelli E, Wu DJ, Sacchetti C, Gujar R, Seumois G, Kiosses WB, Aubry I, Kim G, Mydel P, Sakaguchi S, Kronenberg M, Tiganis T, [...] Bottini N
J Clin Invest, 129(3):1193-1210, 11 Feb 2019
Cited by: 31 articles | PMID: 30620725 | PMCID: PMC6391091
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Age-Related Decline in Primary CD8⁺ T Cell Responses Is Associated with the Development of Senescence in Virtual Memory CD8⁺ T Cells.
Quinn KM, Fox A, Harland KL, Russ BE, Li J, Nguyen THO, Loh L, Olshanksy M, Naeem H, Tsyganov K, Wiede F, Webster R, Blyth C, Sng XYX, Tiganis T, Powell D, Doherty PC, Turner SJ, Kedzierska K, La Gruta NL
Cell Rep, 23(12):3512-3524, 01 Jun 2018
Cited by: 150 articles | PMID: 29924995
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Isolation and Characterization of Mouse Intrahepatic Lymphocytes by Flow Cytometry.
Wiede F, Tiganis T
Methods Mol Biol, 1725:301-311, 01 Jan 2018
Cited by: 4 articles | PMID: 29322426
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Differential regulation of protein tyrosine kinase signalling by Dock and the PTP61F variants.
Willoughby LF, Manent J, Allan K, Lee H, Portela M, Wiede F, Warr C, Meng TC, Tiganis T, Richardson HE
FEBS J, 284(14):2231-2250, 30 Jun 2017
Cited by: 3 articles | PMID: 28544778
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