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Compounds targeting OSBPL7 increase ABCA1-dependent cholesterol efflux preserving kidney function in two models of kidney disease.
Wright MB, Varona Santos J, Kemmer C, Maugeais C, Carralot JP, Roever S, Molina J, Ducasa GM, Mitrofanova A, Sloan A, Ahmad A, Pedigo C, Ge M, Pressly J, Barisoni L, Mendez A, Sgrignani J, Cavalli A, Merscher S, [...] Fornoni A
Nat Commun, 12(1):4662, 02 Aug 2021
Cited by: 25 articles | PMID: 34341345 | PMCID: PMC8329197
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Pioglitazone Ameliorates Gentamicin Ototoxicity by Affecting the TLR and STAT Pathways in the Early Postnatal Organ of Corti.
Sekulic-Jablanovic M, Wright MB, Petkovic V, Bodmer D
Front Cell Neurosci, 14:566148, 29 Oct 2020
Cited by: 2 articles | PMID: 33192313 | PMCID: PMC7658481
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Dual PPARα/γ agonist aleglitazar confers stroke protection in a model of mild focal brain ischemia in mice.
Boujon V, Uhlemann R, Wegner S, Wright MB, Laufs U, Endres M, Kronenberg G, Gertz K
J Mol Med (Berl), 97(8):1127-1138, 30 May 2019
Cited by: 8 articles | PMID: 31147725 | PMCID: PMC6647083
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Insulin Receptor and Glucose Transporters in the Mammalian Cochlea.
Huerzeler N, Petkovic V, Sekulic-Jablanovic M, Kucharava K, Wright MB, Bodmer D
Audiol Neurootol, 24(2):65-76, 22 May 2019
Cited by: 10 articles | PMID: 31117067
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Pioglitazone Represents an Effective Therapeutic Target in Preventing Oxidative/Inflammatory Cochlear Damage Induced by Noise Exposure.
Paciello F, Fetoni AR, Rolesi R, Wright MB, Grassi C, Troiani D, Paludetti G
Front Pharmacol, 9:1103, 08 Oct 2018
Cited by: 20 articles | PMID: 30349478 | PMCID: PMC6187064
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Effects of peroxisome proliferator activated receptors (PPAR)-γ and -α agonists on cochlear protection from oxidative stress.
Sekulic-Jablanovic M, Petkovic V, Wright MB, Kucharava K, Huerzeler N, Levano S, Brand Y, Leitmeyer K, Glutz A, Bausch A, Bodmer D
PLoS One, 12(11):e0188596, 28 Nov 2017
Cited by: 30 articles | PMID: 29182629 | PMCID: PMC5705132
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Urine Drug Testing in a Family Medicine Residency Practice.
Woodall HE, Young N, Davis A, Wright MB
J Addict Med, 11(3):242-243, 01 May 2017
Cited by: 1 article | PMID: 28557961
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Teaching Chronic Pain in Family Medicine.
Davis A, Wright MB, Norris L, Woodall H, Young N, Family Medicine Residency Program AH
Fam Med, 48(10):825, 01 Nov 2016
Cited by: 0 articles | PMID: 27875614
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Pasireotide prevents nuclear factor of activated T cells nuclear translocation and acts as a protective agent in aminoglycoside-induced auditory hair cell loss.
Bodmer D, Perkovic A, Sekulic-Jablanovic M, Wright MB, Petkovic V
J Neurochem, 139(6):1113-1123, 29 Nov 2016
Cited by: 5 articles | PMID: 27787949
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Aldosterone Antagonists or Renin-Guided Therapy for Treatment-Resistant Hypertension: A Comparative Effectiveness Pilot Study in Primary Care.
Egan BM, Laken MA, Sutherland SE, Qanungo S, Fleming DO, Cook AG, Hester WH, Jones KW, Jebaily GC, Valainis GT, Way CF, Wright MB, Davis RA
Am J Hypertens, 29(8):976-983, 13 Apr 2016
Cited by: 2 articles | PMID: 27076600 | PMCID: PMC4941594
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Effects of pioglitazone and fenofibrate co-administration on bone biomechanics and histomorphometry in ovariectomized rats.
Smith SY, Samadfam R, Chouinard L, Awori M, Bénardeau A, Bauss F, Guldberg RE, Sebokova E, Wright MB
J Bone Miner Metab, 33(6):625-641, 23 Dec 2014
Cited by: 5 articles | PMID: 25534548
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Minireview: Challenges and opportunities in development of PPAR agonists.
Wright MB, Bortolini M, Tadayyon M, Bopst M
Mol Endocrinol, 28(11):1756-1768, 22 Aug 2014
Cited by: 88 articles | PMID: 25148456 | PMCID: PMC5414793
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The dual PPARα/γ agonist aleglitazar increases the number and function of endothelial progenitor cells: implications for vascular function and atherogenesis.
Werner CM, Schirmer SH, Gensch C, Pavlickova V, Pöss J, Wright MB, Böhm M, Laufs U
Br J Pharmacol, 171(10):2685-2703, 01 May 2014
Cited by: 21 articles | PMID: 24467636 | PMCID: PMC4009009
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6-Alkoxy-5-aryl-3-pyridinecarboxamides, a new series of bioavailable cannabinoid receptor type 1 (CB1) antagonists including peripherally selective compounds.
Röver S, Andjelkovic M, Bénardeau A, Chaput E, Guba W, Hebeisen P, Mohr S, Nettekoven M, Obst U, Richter WF, Ullmer C, Waldmeier P, Wright MB
J Med Chem, 56(24):9874-9896, 20 Nov 2013
Cited by: 15 articles | PMID: 24175572
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Examining the safety of PPAR agonists - current trends and future prospects.
Bortolini M, Wright MB, Bopst M, Balas B
Expert Opin Drug Saf, 12(1):65-79, 08 Nov 2012
Cited by: 39 articles | PMID: 23134541
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Effects of the dual PPAR-α/γ agonist aleglitazar on glycaemic control and organ protection in the Zucker diabetic fatty rat.
Bénardeau A, Verry P, Atzpodien EA, Funk JM, Meyer M, Mizrahi J, Winter M, Wright MB, Uhles S, Sebokova E
Diabetes Obes Metab, 15(2):164-174, 03 Oct 2012
Cited by: 11 articles | PMID: 22958363
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Comparative transcriptional network modeling of three PPAR-α/γ co-agonists reveals distinct metabolic gene signatures in primary human hepatocytes.
Deehan R, Maerz-Weiss P, Catlett NL, Steiner G, Wong B, Wright MB, Blander G, Elliston KO, Ladd W, Bobadilla M, Mizrahi J, Haefliger C, Edgar A
PLoS One, 7(4):e35012, 13 Apr 2012
Cited by: 12 articles | PMID: 22514701 | PMCID: PMC3325914
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Comparative molecular profiling of the PPARα/γ activator aleglitazar: PPAR selectivity, activity and interaction with cofactors.
Dietz M, Mohr P, Kuhn B, Maerki HP, Hartman P, Ruf A, Benz J, Grether U, Wright MB
ChemMedChem, 7(6):1101-1111, 04 Apr 2012
Cited by: 26 articles | PMID: 22489042 | PMCID: PMC3504387
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Farnesoid X receptor protects human and murine gastric epithelial cells against inflammation-induced damage.
Lian F, Xing X, Yuan G, Schäfer C, Rauser S, Walch A, Röcken C, Ebeling M, Wright MB, Schmid RM, Ebert MP, Burgermeister E
Biochem J, 438(2):315-323, 01 Sep 2011
Cited by: 34 articles | PMID: 21619550
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The Ras inhibitors caveolin-1 and docking protein 1 activate peroxisome proliferator-activated receptor γ through spatial relocalization at helix 7 of its ligand-binding domain.
Burgermeister E, Friedrich T, Hitkova I, Regel I, Einwächter H, Zimmermann W, Röcken C, Perren A, Wright MB, Schmid RM, Seger R, Ebert MP
Mol Cell Biol, 31(16):3497-3510, 20 Jun 2011
Cited by: 30 articles | PMID: 21690289 | PMCID: PMC3147789
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New Insights on the mechanism of PPAR-targeted drugs.
Grether U, Klaus W, Kuhn B, Maerki HP, Mohr P, Wright MB
ChemMedChem, 5(12):1973-1976, 01 Dec 2010
Cited by: 6 articles | PMID: 21069658
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Discovery of novel and potent leukotriene B4 receptor antagonists. Part 1.
Goodnow RA, Hicks A, Sidduri A, Kowalczyk A, Dominique R, Qiao Q, Lou JP, Gillespie P, Fotouhi N, Tilley J, Cohen N, Choudhry S, Cavallo G, Tannu SA, Ventre JD, Lavelle D, Tare NS, Oh H, Lamb M, [...] Renzetti LM
J Med Chem, 53(9):3502-3516, 01 May 2010
Cited by: 3 articles | PMID: 20380377
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Recent progress in liver X receptor-selective modulators.
Ratni H, Wright MB
Curr Opin Drug Discov Devel, 13(4):403-413, 01 Jul 2010
Cited by: 7 articles | PMID: 20597026
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MARCO, a macrophage scavenger receptor highly expressed in rodents, mediates dalcetrapib-induced uptake of lipids by rat and mouse macrophages.
Perez A, Wright MB, Maugeais C, Braendli-Baiocco A, Okamoto H, Takahashi A, Singer T, Mueller L, Niesor EJ
Toxicol In Vitro, 24(3):745-750, 13 Jan 2010
Cited by: 9 articles | PMID: 20074633
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Effects of LTB4 receptor antagonism on pulmonary inflammation in rodents and non-human primates.
Hicks A, Goodnow R, Cavallo G, Tannu SA, Ventre JD, Lavelle D, Lora JM, Satjawatcharaphong J, Brovarney M, Dabbagh K, Tare NS, Oh H, Lamb M, Sidduri A, Dominique R, Qiao Q, Lou JP, Gillespie P, Fotouhi N, [...] Renzetti LM
Prostaglandins Other Lipid Mediat, 92(1-4):33-43, 07 Mar 2010
Cited by: 15 articles | PMID: 20214997
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