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DMC1 and RAD51 bind FxxA and FxPP motifs of BRCA2 via two separate interfaces.
Miron S, Legrand P, Dupaigne P, van Rossum-Fikkert SE, Ristic D, Majeed A, Kanaar R, Zinn-Justin S, Zelensky AN
Nucleic Acids Res, 52(12):7337-7353, 01 Jul 2024
Cited by: 0 articles | PMID: 38828772 | PMCID: PMC11229353
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The BRCA2 R2645G variant increases DNA binding and induces hyper-recombination.
Alvaro-Aranda L, Petitalot A, Djeghmoum Y, Panigada D, Singh JK, Ehlén Å, Vugic D, Martin C, Miron S, Contreras-Perez A, Nhiri N, Boucherit V, Lafitte P, Dumoulin I, Quiles F, Rouleau E, Jacquet E, Feliubadaló L, Del Valle J, [...] Carreira A
Nucleic Acids Res, 52(12):6964-6976, 01 Jul 2024
Cited by: 0 articles | PMID: 38142462 | PMCID: PMC11229362
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KIF2C-induced nuclear condensation concentrates PLK1 and phosphorylated BRCA2 at the kinetochore microtubules in mitosis
Skobelkina A, Julien M, Jeannin S, Miron S, Egger T, Chaaban R, Bouvignies G, Ghouil R, Friel C, Busso D, Theillet F, Le Bars R, Carreira A, Constantinou A, Basbous J, Zinn-Justin S
bioRxiv, 14 Apr 2024
Cited by: 0 articles | PPR: PPR837705
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Publisher Correction: Polθ is phosphorylated by PLK1 to repair double-strand breaks in mitosis.
Gelot C, Kovacs MT, Miron S, Mylne E, Haan A, Boeffard-Dosierre L, Ghouil R, Popova T, Dingli F, Loew D, Guirouilh-Barbat J, Del Nery E, Zinn-Justin S, Ceccaldi R
Nature, 626(7999):E13, 01 Feb 2024
Cited by: 0 articles | PMID: 38273133 | PMCID: PMC10866694
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BRCA2-HSF2BP oligomeric ring disassembly by BRME1 promotes homologous recombination.
Ghouil R, Miron S, Sato K, Ristic D, van Rossum-Fikkert SE, Legrand P, Ouldali M, Winter JM, Ropars V, David G, Arteni AA, Wyman C, Knipscheer P, Kanaar R, Zelensky AN, Zinn-Justin S
Sci Adv, 9(43):eadi7352, 27 Oct 2023
Cited by: 2 articles | PMID: 37889963 | PMCID: PMC10610910
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Chromosome Pairing Through Tensioned DNA Tethers Revealed by BRCA2 Meiotic Domain Deletion
Koornneef L, van Rossum-Fikkert SE, Sleddens-Linkels E, Miron S, Maas A, van Loon Y, Barchi M, Zinn-Justin S, Essers J, Kanaar R, Baarends WM, Zelensky AN
bioRxiv, 06 Oct 2023
Cited by: 0 articles | PPR: PPR738127
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DMC1 and RAD51 bind FxxA and FxPP motifs of BRCA2 via two separate interfaces
Miron S, Legrand P, van Rossum-Fikkert SE, Ristic D, Badar A, Kanaar R, Zinn-Justin S, Zelensky AN
bioRxiv, 05 Oct 2023
Cited by: 0 articles | PPR: PPR737417
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Polθ is phosphorylated by PLK1 to repair double-strand breaks in mitosis.
Gelot C, Kovacs MT, Miron S, Mylne E, Haan A, Boeffard-Dosierre L, Ghouil R, Popova T, Dingli F, Loew D, Guirouilh-Barbat J, Del Nery E, Zinn-Justin S, Ceccaldi R
Nature, 621(7978):415-422, 06 Sep 2023
Cited by: 27 articles | PMID: 37674080 | PMCID: PMC10499603
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WWOX binds MERIT40 and modulates its function in homologous recombination, implications in breast cancer.
Taouis K, Vacher S, Guirouilh-Barbat J, Camonis J, Formstecher E, Popova T, Hamy AS, Petitalot A, Lidereau R, Caputo SM, Zinn-Justin S, Bièche I, Driouch K, Lallemand F
Cancer Gene Ther, 30(8):1144-1155, 29 May 2023
Cited by: 1 article | PMID: 37248434 | PMCID: PMC10425285
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BRCA2-HSF2BP Oligomeric Ring Disassembly by BRME1 Promotes Homologous Recombination
Ghouil R, Miron S, Sato K, Ristic D, van Rossum-Fikkert SE, Legrand P, Ouldali M, Winter J, Ropars V, David G, Arteni A, Wyman C, Knipscheer P, Kanaar R, Zelensky AN, Zinn-Justin S
bioRxiv, 28 Apr 2023
Cited by: 0 articles | PPR: PPR652759
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Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis
Gelot C, Kovacs MT, Miron S, Mylne E, Ghouil R, Popova T, Dingli F, Loew D, Guirouilh-Barbat J, Del Nery E, Zinn-Justin S, Ceccaldi R
bioRxiv, 19 Mar 2023
Cited by: 0 articles | PPR: PPR632282
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A De Novo Sequence Variant in Barrier-to-Autointegration Factor Is Associated with Dominant Motor Neuronopathy.
Marcelot A, Rodriguez-Tirado F, Cuniasse P, Joiner ML, Miron S, Soshnev AA, Fang M, Pufall MA, Mathews KD, Moore SA, Zinn-Justin S, Geyer PK
Cells, 12(6):847, 09 Mar 2023
Cited by: 2 articles | PMID: 36980188 | PMCID: PMC10099716
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The Conformation of the Intrinsically Disordered N-Terminal Region of Barrier-to-Autointegration Factor (BAF) is Regulated by pH and Phosphorylation.
Marcelot A, Zinn-Justin S, Cuniasse P
J Mol Biol, 435(2):167888, 17 Nov 2022
Cited by: 2 articles | PMID: 36402223
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WWOX Binds MERIT40 and Modulates Its Function in Homologous Recombination, Implications in Breast Cancer
Lallemand F, Taouis K, Vacher S, Guirouilh-Barbat J, Camonis J, Formstecher E, Popova T, Hamy A, Petitalot A, Lidereau R, Caputo S, Zinn-Justin S, Bieche I, DRIOUCH K
Research Square, 12 Dec 2022
Cited by: 0 articles | PPR: PPR583966
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Structural analysis of Toxoplasma gondiisortilin
Honfozo A, Ghouil R, Alayi TD, Ouldali M, Arteni A, Atindehou CM, Fanou LA, Hathout Y, Zinn-Justin S, Tomavo S
bioRxiv, 21 Nov 2022
Cited by: 0 articles | PPR: PPR574292
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The BAF A12T mutation disrupts lamin A/C interaction, impairing robust repair of nuclear envelope ruptures in Nestor-Guillermo progeria syndrome cells.
Janssen A, Marcelot A, Breusegem S, Legrand P, Zinn-Justin S, Larrieu D
Nucleic Acids Res, 50(16):9260-9278, 01 Sep 2022
Cited by: 11 articles | PMID: 36039758 | PMCID: PMC9458464
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Dissecting the roles of Haspin and VRK1 in histone H3 phosphorylation during mitosis.
Cartwright TN, Harris RJ, Meyer SK, Mon AM, Watson NA, Tan C, Marcelot A, Wang F, Zinn-Justin S, Traktman P, Higgins JMG
Sci Rep, 12(1):11210, 01 Jul 2022
Cited by: 4 articles | PMID: 35778595 | PMCID: PMC9249732
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The BAF A12T mutation associated with premature aging impedes lamin A/C recruitment to sites of nuclear rupture, contributing to nuclear envelope fragility
Janssen A, Marcelot A, Breusegem S, Legrand P, Zinn-Justin S, Larrieu D
bioRxiv, 25 Feb 2022
Cited by: 0 articles | PPR: PPR461938
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Lamin B1 sequesters 53BP1 to control its recruitment to DNA damage.
Etourneaud L, Moussa A, Rass E, Genet D, Willaume S, Chabance-Okumura C, Wanschoor P, Picotto J, Thézé B, Dépagne J, Veaute X, Dizet E, Busso D, Barascu A, Irbah L, Kortulewski T, Campalans A, Le Chalony C, Zinn-Justin S, [...] Bertrand P
Sci Adv, 7(35):eabb3799, 27 Aug 2021
Cited by: 17 articles | PMID: 34452908 | PMCID: PMC8397269
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BRCA2 binding through a cryptic repeated motif to HSF2BP oligomers does not impact meiotic recombination.
Ghouil R, Miron S, Koornneef L, Veerman J, Paul MW, Le Du MH, Sleddens-Linkels E, van Rossum-Fikkert SE, van Loon Y, Felipe-Medina N, Pendas AM, Maas A, Essers J, Legrand P, Baarends WM, Kanaar R, Zinn-Justin S, Zelensky AN
Nat Commun, 12(1):4605, 29 Jul 2021
Cited by: 8 articles | PMID: 34326328 | PMCID: PMC8322138
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Intrinsic Disorder and Phosphorylation in BRCA2 Facilitate Tight Regulation of Multiple Conserved Binding Events.
Julien M, Ghouil R, Petitalot A, Caputo SM, Carreira A, Zinn-Justin S
Biomolecules, 11(7):1060, 20 Jul 2021
Cited by: 6 articles | PMID: 34356684 | PMCID: PMC8301801
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Mechanism of MRX inhibition by Rif2 at telomeres.
Roisné-Hamelin F, Pobiega S, Jézéquel K, Miron S, Dépagne J, Veaute X, Busso D, Du ML, Callebaut I, Charbonnier JB, Cuniasse P, Zinn-Justin S, Marcand S
Nat Commun, 12(1):2763, 12 May 2021
Cited by: 12 articles | PMID: 33980827 | PMCID: PMC8115599
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Di-phosphorylated BAF shows altered structural dynamics and binding to DNA, but interacts with its nuclear envelope partners.
Marcelot A, Petitalot A, Ropars V, Le Du MH, Samson C, Dubois S, Hoffmann G, Miron S, Cuniasse P, Marquez JA, Thai R, Theillet FX, Zinn-Justin S
Nucleic Acids Res, 49(7):3841-3855, 01 Apr 2021
Cited by: 20 articles | PMID: 33744941 | PMCID: PMC8053085
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The phospho-dependent role of BRCA2 on the maintenance of chromosome integrity.
Ehlén Å, Sessa G, Zinn-Justin S, Carreira A
Cell Cycle, 20(8):731-741, 10 Mar 2021
Cited by: 3 articles | PMID: 33691600 | PMCID: PMC8098065
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A cryptic BRCA2 repeated motif binds to HSF2BP oligomers with no impact on meiotic recombination
Ghouil R, Miron S, Koornneef L, Veerman J, Paul MW, Le Du M, Sleddens-Linkels E, van Rossum-Fikkert SE, van Loon Y, Felipe-Medina N, Pendas AM, Maas A, Essers J, Legrand P, Baarends WM, Kanaar R, Zinn-Justin S, Zelensky AN
bioRxiv, 29 Dec 2020
Cited by: 0 articles | PPR: PPR259229
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1-25 of 116 results

1 2 3 Next ...

Search life-sciences literature (45,103,589 articles, preprints and more)

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DMC1 and RAD51 bind FxxA and FxPP motifs of BRCA2 via two separate interfaces.

The BRCA2 R2645G variant increases DNA binding and induces hyper-recombination.

KIF2C-induced nuclear condensation concentrates PLK1 and phosphorylated BRCA2 at the kinetochore microtubules in mitosis

Publisher Correction: Polθ is phosphorylated by PLK1 to repair double-strand breaks in mitosis.

BRCA2-HSF2BP oligomeric ring disassembly by BRME1 promotes homologous recombination.

Chromosome Pairing Through Tensioned DNA Tethers Revealed by BRCA2 Meiotic Domain Deletion

DMC1 and RAD51 bind FxxA and FxPP motifs of BRCA2 via two separate interfaces

Polθ is phosphorylated by PLK1 to repair double-strand breaks in mitosis.

WWOX binds MERIT40 and modulates its function in homologous recombination, implications in breast cancer.

BRCA2-HSF2BP Oligomeric Ring Disassembly by BRME1 Promotes Homologous Recombination

Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis

A De Novo Sequence Variant in Barrier-to-Autointegration Factor Is Associated with Dominant Motor Neuronopathy.

The Conformation of the Intrinsically Disordered N-Terminal Region of Barrier-to-Autointegration Factor (BAF) is Regulated by pH and Phosphorylation.

WWOX Binds MERIT40 and Modulates Its Function in Homologous Recombination, Implications in Breast Cancer

Structural analysis of Toxoplasma gondiisortilin

The BAF A12T mutation disrupts lamin A/C interaction, impairing robust repair of nuclear envelope ruptures in Nestor-Guillermo progeria syndrome cells.

Dissecting the roles of Haspin and VRK1 in histone H3 phosphorylation during mitosis.

The BAF A12T mutation associated with premature aging impedes lamin A/C recruitment to sites of nuclear rupture, contributing to nuclear envelope fragility

Lamin B1 sequesters 53BP1 to control its recruitment to DNA damage.

BRCA2 binding through a cryptic repeated motif to HSF2BP oligomers does not impact meiotic recombination.

Intrinsic Disorder and Phosphorylation in BRCA2 Facilitate Tight Regulation of Multiple Conserved Binding Events.

Mechanism of MRX inhibition by Rif2 at telomeres.

Di-phosphorylated BAF shows altered structural dynamics and binding to DNA, but interacts with its nuclear envelope partners.

The phospho-dependent role of BRCA2 on the maintenance of chromosome integrity.

A cryptic BRCA2 repeated motif binds to HSF2BP oligomers with no impact on meiotic recombination

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