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A single-dose intranasal live-attenuated codon deoptimized vaccine provides broad protection against SARS-CoV-2 and its variants.
Liu X, Ng WH, Zusinaite E, Freitas J, Taylor A, Yerragunta V, Aavula SM, Gorriparthi S, Ponsekaran S, Bonda RL, Mani P, Nimmagadda SV, Wang S, Lello LS, Zaid A, Dua U, Taft-Benz SA, Anderson E, Baxter VK, [...] Mahalingam S
Nat Commun, 15(1):7225, 26 Aug 2024
Cited by: 0 articles | PMID: 39187479 | PMCID: PMC11347628
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The combination of pleconaril, rupintrivir, and remdesivir efficiently inhibits enterovirus infections in vitro, delaying the development of drug-resistant virus variants.
Ianevski A, Frøysa IT, Lysvand H, Calitz C, Smura T, Schjelderup Nilsen HJ, Høyer E, Afset JE, Sridhar A, Wolthers KC, Zusinaite E, Tenson T, Kurg R, Oksenych V, Galabov AS, Stoyanova A, Bjørås M, Kainov DE
Antiviral Res, 224:105842, 26 Feb 2024
Cited by: 1 article | PMID: 38417531
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Dimeric Bis-Benzimidazole-Pyrroles DB2Py(n) - AT-Site-Specific Ligands: Synthesis, Physicochemical Analysis, and Biological Activity.
Susova OY, Karshieva SS, Kostyukov AA, Moiseeva NI, Zaytseva EA, Kalabina KV, Zusinaite E, Gildemann K, Smirnov NM, Arutyunyan AF, Zhuze AL
Acta Naturae, 16(1):86-100, 01 Jan 2024
Cited by: 0 articles | PMID: 38698958 | PMCID: PMC11062108
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Boosted production of antibodies that neutralized different SARS-CoV-2 variants in a COVID-19 convalescent following messenger RNA vaccination - a case study.
Ravlo E, Ianevski A, Starheim E, Wang W, Ji P, Lysvand H, Smura T, Kivi G, Voolaid ML, Plaan K, Ustav M, Ustav M, Zusinaite E, Tenson T, Kurg R, Oksenych V, Walstad K, Nordbø SA, Kaarbø M, [...] Fenstad MH
Int J Infect Dis, 137:75-78, 17 Oct 2023
Cited by: 0 articles | PMID: 37852599
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Antiviral efficacy of nanomaterial-treated textiles in real-life like exposure conditions.
Nefedova A, Rausalu K, Zusinaite E, Kisand V, Kook M, Smits K, Vanetsev A, Ivask A
Heliyon, 9(9):e20067, 12 Sep 2023
Cited by: 0 articles | PMID: 37810009 | PMCID: PMC10559815
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Broadly neutralizing humanized SARS-CoV-2 antibody binds to a conserved epitope on Spike and provides antiviral protection through inhalation-based delivery in non-human primates.
Hermet P, Delache B, Herate C, Wolf E, Kivi G, Juronen E, Mumm K, Žusinaite E, Kainov D, Sankovski E, Virumäe K, Planken A, Merits A, Besaw JE, Yee AW, Morizumi T, Kim K, Kuo A, Berriche A, [...] Ustav M
PLoS Pathog, 19(8):e1011532, 02 Aug 2023
Cited by: 2 articles | PMID: 37531329 | PMCID: PMC10395824
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A Zika virus-responsive sensor-effector system inAedes aegypti
Basu S, Reitmayer CM, Lumley S, Atkinson B, Schade-Weskott ML, Rooney S, Larner W, Montiel EE, Gutiérrez-López R, Levitt E, Munyanduki HM, Mohamed AME, Clarke AT, Koit S, Zusinaite E, Fragkoudis R, Merits A, Alphey L
bioRxiv, 06 Feb 2023
Cited by: 0 articles | PPR: PPR612854
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Antiviral efficacy of cerium oxide nanoparticles.
Nefedova A, Rausalu K, Zusinaite E, Vanetsev A, Rosenberg M, Koppel K, Lilla S, Visnapuu M, Smits K, Kisand V, Tätte T, Ivask A
Sci Rep, 12(1):18746, 05 Nov 2022
Cited by: 9 articles | PMID: 36335167 | PMCID: PMC9637224
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Seven classes of antiviral agents.
Ianevski A, Ahmad S, Anunnitipat K, Oksenych V, Zusinaite E, Tenson T, Bjørås M, Kainov DE
Cell Mol Life Sci, 79(12):605, 27 Nov 2022
Cited by: 4 articles | PMID: 36436108 | PMCID: PMC9701656
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Antibacterial and Antiviral Effects of Ag, Cu and Zn Metals, Respective Nanoparticles and Filter Materials Thereof against Coronavirus SARS-CoV-2 and Influenza A Virus.
Kubo AL, Rausalu K, Savest N, Žusinaite E, Vasiliev G, Viirsalu M, Plamus T, Krumme A, Merits A, Bondarenko O
Pharmaceutics, 14(12):2549, 22 Nov 2022
Cited by: 8 articles | PMID: 36559043 | PMCID: PMC9785359
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Novel Synergistic Anti-Enteroviral Drug Combinations
Ianevski A, Zusinaite E, Tenson T, Oksenych V, Wang W, Afset JE, Bjørås M, Kainov DE
Preprints.org, 02 Aug 2022
Cited by: 0 articles | PPR: PPR527235
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Novel Synergistic Anti-Enteroviral Drug Combinations.
Ianevski A, Zusinaite E, Tenson T, Oksenych V, Wang W, Afset JE, Bjørås M, Kainov DE
Viruses, 14(9):1866, 25 Aug 2022
Cited by: 6 articles | PMID: 36146673 | PMCID: PMC9505890
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Protective antibodies and T cell responses to Omicron variant after the booster dose of BNT162b2 vaccine.
Naaber P, Tserel L, Kangro K, Punapart M, Sepp E, Jürjenson V, Kärner J, Haljasmägi L, Haljasorg U, Kuusk M, Sankovski E, Planken A, Ustav M, Žusinaite E, Gerhold JM, Kisand K, Peterson P
Cell Rep Med, 3(8):100716, 04 Aug 2022
Cited by: 15 articles | PMID: 35952669 | PMCID: PMC9350667
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Bovine colostrum-derived antibodies against SARS-CoV-2 show great potential to serve as prophylactic agents.
Kangro K, Kurašin M, Gildemann K, Sankovski E, Žusinaite E, Lello LS, Pert R, Kavak A, Poikalainen V, Lepasalu L, Kuusk M, Pau R, Piiskop S, Rom S, Oltjer R, Tiirik K, Kogermann K, Plaas M, Tiirats T, [...] Ustav M
PLoS One, 17(6):e0268806, 10 Jun 2022
Cited by: 11 articles | PMID: 35687549 | PMCID: PMC9187060
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Broad-spectrum mono- and combinational drug therapies for global viral pandemic preparedness
Ianevski A, Yao R, Simonsen RM, Myhre V, Ravlo E, Kaynova GD, Zusinaite E, White JM, Polyak SJ, Oksenych V, Windisch MP, Pan Q, Lastauskienė E, Vitkauskienė A, Matukevičius A, Tenson T, Bjørås M, Kainov DE
bioRxiv, 15 Jan 2022
Cited by: 0 articles | PPR: PPR443259
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Mono- and combinational drug therapies for global viral pandemic preparedness.
Ianevski A, Yao R, Simonsen RM, Myhre V, Ravlo E, Kaynova GD, Zusinaite E, White JM, Polyak SJ, Oksenych V, Windisch MP, Pan Q, Lastauskienė E, Vitkauskienė A, Matukevičius A, Tenson T, Bjørås M, Kainov DE
iScience, 25(4):104112, 17 Mar 2022
Cited by: 18 articles | PMID: 35402870 | PMCID: PMC8983340
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Antiviral efficacy of cerium oxide nanoparticles
Nefedova A, Rausalu K, Zusinaite E, Vanetsev A, Rosenberg M, Koppel K, Lilla S, Visnapuu M, Šmits K, Kisand V, Tätte T, Ivask A
Research Square, 25 Feb 2022
Cited by: 0 articles | PPR: PPR461722
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Synergistic Interferon-Alpha-Based Combinations for Treatment of SARS-CoV-2 and Other Viral Infections.
Ianevski A, Yao R, Zusinaite E, Lello LS, Wang S, Jo E, Yang J, Ravlo E, Wang W, Lysvand H, Løseth K, Oksenych V, Tenson T, Windisch MP, Poranen MM, Nieminen AI, Nordbø SA, Fenstad MH, Grødeland G, [...] Kainov DE
Viruses, 13(12):2489, 11 Dec 2021
Cited by: 19 articles | PMID: 34960758 | PMCID: PMC8705725
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Nafamostat-Interferon-α Combination Suppresses SARS-CoV-2 Infection In Vitro and In Vivo by Cooperatively Targeting Host TMPRSS2.
Ianevski A, Yao R, Lysvand H, Grødeland G, Legrand N, Oksenych V, Zusinaite E, Tenson T, Bjørås M, Kainov DE
Viruses, 13(9):1768, 04 Sep 2021
Cited by: 14 articles | PMID: 34578348 | PMCID: PMC8473362
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Long-Term Elevated Inflammatory Protein Levels in Asymptomatic SARS-CoV-2 Infected Individuals.
Tserel L, Jõgi P, Naaber P, Maslovskaja J, Häling A, Salumets A, Zusinaite E, Soeorg H, Lättekivi F, Ingerainen D, Soots M, Toompere K, Kaarna K, Kisand K, Lutsar I, Peterson P
Front Immunol, 12:709759, 17 Sep 2021
Cited by: 11 articles | PMID: 34603283 | PMCID: PMC8484961
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Nafamostat-interferon-alpha combination suppresses SARS-CoV-2 infection by targeting cooperatively host TMPRSS2 in vitro and in vivo
Ianevski A, Yao R, Lysvand H, Grødeland G, Legrand N, Oksenych V, Zusinaite E, Tenson T, Bjørås M, Kainov DE
bioRxiv, 16 Jun 2021
Cited by: 0 articles | PPR: PPR357434
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Active Components of Commonly Prescribed Medicines Affect Influenza A Virus-Host Cell Interaction: A Pilot Study.
Ianevski A, Yao R, Zusinaite E, Lysvand H, Oksenych V, Tenson T, Bjørås M, Kainov D
Viruses, 13(8):1537, 03 Aug 2021
Cited by: 4 articles | PMID: 34452402 | PMCID: PMC8402715
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Semliki Forest Virus Chimeras with Functional Replicase Modules from Related Alphaviruses Survive by Adaptive Mutations in Functionally Important Hot Spots.
Teppor M, Žusinaite E, Karo-Astover L, Omler A, Rausalu K, Lulla V, Lulla A, Merits A
J Virol, 95(20):e0097321, 28 Jul 2021
Cited by: 4 articles | PMID: 34319778 | PMCID: PMC8475518
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Active Components of Commonly Prescribed Medicines Affect Influenza a Virus-Host Cell Interaction: A Pilot Study
Ianevski A, Yao R, Zusinaite E, Lysvand H, Oksenych V, Tenson T, Bjørås M, Kainov D
Preprints.org, 12 Jul 2021
Cited by: 0 articles | PPR: PPR368954
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Prevalence of SARS-CoV-2 IgG antibodies and their association with clinical symptoms of COVID-19 in Estonia (KoroSero-EST-1 study).
Jõgi P, Soeorg H, Ingerainen D, Soots M, Lättekivi F, Naaber P, Toompere K, Peterson P, Haljasmägi L, Žusinaite E, Vaas H, Pauskar M, Shablinskaja A, Kaarna K, Paluste H, Kisand K, Oona M, Janno R, Lutsar I
Vaccine, 39(38):5376-5384, 05 Aug 2021
Cited by: 8 articles | PMID: 34393019 | PMCID: PMC8339569
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