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Search life-sciences literature (45,104,206 articles, preprints and more)

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Advances in the mechanism of small nucleolar RNA and its role in DNA damage response.
Shen LP, Zhang WC, Deng JR, Qi ZH, Lin ZW, Wang ZD
Mil Med Res, 11(1):53, 08 Aug 2024
Cited by: 1 article | PMID: 39118131 | PMCID: PMC11308251
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Retinol Binding Protein 4 Serves as a Potential Tumor Biomarker and Promotes Malignant Behavior in Gastric Cancer.
Yu Y, Zhang C, Sun Q, Baral S, Ding J, Zhao F, Yao Q, Gao S, Liu B, Wang D
Cancer Manag Res, 16:891-908, 24 Jul 2024
Cited by: 0 articles | PMID: 39072342 | PMCID: PMC11283833
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The Pharmacological Implications of Flavopiridol: An Updated Overview.
Joshi H, Tuli HS, Ranjan A, Chauhan A, Haque S, Ramniwas S, Bhatia GK, Kandari D
Molecules, 28(22):7530, 10 Nov 2023
Cited by: 2 articles | PMID: 38005250
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5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole (DRB) induces apoptosis in breast cancer cells through inhibiting of Mcl-1 expression.
Kuo YH, Lai TC, Chang CH, Hsieh HC, Yang FM, Hu MC
Sci Rep, 13(1):12621, 03 Aug 2023
Cited by: 1 article | PMID: 37537243 | PMCID: PMC10400577
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Nuclear oligo hashing improves differential analysis of single-cell RNA-seq.
Kim HJ, Booth G, Saunders L, Srivatsan S, McFaline-Figueroa JL, Trapnell C
Nat Commun, 13(1):2666, 13 May 2022
Cited by: 1 article | PMID: 35562344 | PMCID: PMC9106741
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Inhibitory Response to CK II Inhibitor Silmitasertib and CDKs Inhibitor Dinaciclib Is Related to Genetic Differences in Pancreatic Ductal Adenocarcinoma Cell Lines.
Ma Y, Sender S, Sekora A, Kong W, Bauer P, Ameziane N, Krake S, Radefeldt M, Al-Ali R, Weiss FU, Lerch MM, Parveen A, Zechner D, Junghanss C, Murua Escobar H
Int J Mol Sci, 23(8):4409, 16 Apr 2022
Cited by: 2 articles | PMID: 35457227 | PMCID: PMC9031017
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Chemotherapy Resistance: Role of Mitochondrial and Autophagic Components.
Bahar E, Han SY, Kim JY, Yoon H
Cancers (Basel), 14(6):1462, 12 Mar 2022
Cited by: 23 articles | PMID: 35326612 | PMCID: PMC8945922
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CDK9 inhibitors in multiple myeloma: a review of progress and perspectives.
Borowczak J, Szczerbowski K, Ahmadi N, Szylberg Ł
Med Oncol, 39(4):39, 29 Jan 2022
Cited by: 12 articles | PMID: 35092513 | PMCID: PMC8800928
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Flavopiridol Mitigates the Progression of Monocrotaline-Induced Pulmonary Hypertension in Rats by Targeting Cyclin-Dependent Kinase 9.
Jia Q, Hu Z, Song N, Mao W
Cardiovasc Drugs Ther, 37(3):449-460, 28 Jan 2022
Cited by: 0 articles | PMID: 35088192 | PMCID: PMC10164032
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Chiral Flavonoids as Antitumor Agents.
Pinto C, Cidade H, Pinto M, Tiritan ME
Pharmaceuticals (Basel), 14(12):1267, 05 Dec 2021
Cited by: 7 articles | PMID: 34959668 | PMCID: PMC8704364
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Insights into the post-translational modification and its emerging role in shaping the tumor microenvironment.
Li W, Li F, Zhang X, Lin HK, Xu C
Signal Transduct Target Ther, 6(1):422, 20 Dec 2021
Cited by: 60 articles | PMID: 34924561 | PMCID: PMC8685280
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Targeting the BCL-2-regulated apoptotic pathway for the treatment of solid cancers.
Fairlie WD, Lee EF
Biochem Soc Trans, 49(5):2397-2410, 01 Nov 2021
Cited by: 8 articles | PMID: 34581776 | PMCID: PMC8589438
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Therapeutic Potential of the Cyclin-Dependent Kinase Inhibitor Flavopiridol on c-Myc Overexpressing Esophageal Cancer.
Hassan MS, Cwidak N, Johnson C, Däster S, Eppenberger-Castori S, Awasthi N, Li J, Schwarz MA, von Holzen U
Front Pharmacol, 12:746385, 21 Sep 2021
Cited by: 6 articles | PMID: 34621175 | PMCID: PMC8490822
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Novel CDK9 inhibitor oroxylin A promotes wild-type P53 stability and prevents hepatocellular carcinoma progression by disrupting both MDM2 and SIRT1 signaling.
Yao JY, Xu S, Sun YN, Xu Y, Guo QL, Wei LB
Acta Pharmacol Sin, 43(4):1033-1045, 29 Jun 2021
Cited by: 16 articles | PMID: 34188177 | PMCID: PMC8975870
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An Overview of the Recent Development of Anticancer Agents Targeting the HIF-1 Transcription Factor.
Shirai Y, Chow CCT, Kambe G, Suwa T, Kobayashi M, Takahashi I, Harada H, Nam JM
Cancers (Basel), 13(11):2813, 04 Jun 2021
Cited by: 27 articles | PMID: 34200019 | PMCID: PMC8200185
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Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting.
Pannecoucke E, Van Trimpont M, Desmet J, Pieters T, Reunes L, Demoen L, Vuylsteke M, Loverix S, Vandenbroucke K, Alard P, Henderikx P, Deroo S, Baatz F, Lorent E, Thiolloy S, Somers K, McGrath Y, Van Vlierberghe P, Lasters I, Savvides SN
Sci Adv, 7(13):eabe1682, 26 Mar 2021
Cited by: 3 articles | PMID: 33771865 | PMCID: PMC7997521
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Necroptosis, pyroptosis and apoptosis: an intricate game of cell death.
Bertheloot D, Latz E, Franklin BS
Cell Mol Immunol, 18(5):1106-1121, 30 Mar 2021
Cited by: 601 articles | PMID: 33785842 | PMCID: PMC8008022
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The Role of CDK5 in Tumours and Tumour Microenvironments.
Do PA, Lee CH
Cancers (Basel), 13(1):E101, 31 Dec 2020
Cited by: 21 articles | PMID: 33396266 | PMCID: PMC7795262
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Ubiquitination and deubiquitination of MCL1 in cancer: deciphering chemoresistance mechanisms and providing potential therapeutic options.
Wu X, Luo Q, Liu Z
Cell Death Dis, 11(7):556, 22 Jul 2020
Cited by: 36 articles | PMID: 32699213 | PMCID: PMC7376237
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Fadraciclib (CYC065), a novel CDK inhibitor, targets key pro-survival and oncogenic pathways in cancer.
Frame S, Saladino C, MacKay C, Atrash B, Sheldrake P, McDonald E, Clarke PA, Workman P, Blake D, Zheleva D
PLoS One, 15(7):e0234103, 09 Jul 2020
Cited by: 31 articles | PMID: 32645016 | PMCID: PMC7347136
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Targeting apoptosis in cancer therapy.
Carneiro BA, El-Deiry WS
Nat Rev Clin Oncol, 17(7):395-417, 23 Mar 2020
Cited by: 884 articles | PMID: 32203277 | PMCID: PMC8211386
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Effective Synergy of Sorafenib and Nutrient Shortage in Inducing Melanoma Cell Death through Energy Stress.
Antunes F, Pereira GJS, Saito RF, Buri MV, Gagliardi M, Bincoletto C, Chammas R, Fimia GM, Piacentini M, Corazzari M, Smaili SS
Cells, 9(3):E640, 06 Mar 2020
Cited by: 6 articles | PMID: 32155825 | PMCID: PMC7140454
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Targeting Apoptosis in Acute Myeloid Leukemia: Current Status and Future Directions of BCL-2 Inhibition with Venetoclax and Beyond.
Choi JH, Bogenberger JM, Tibes R
Target Oncol, 15(2):147-162, 01 Apr 2020
Cited by: 21 articles | PMID: 32319019
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Transcriptional Silencing of MCL-1 Through Cyclin-Dependent Kinase Inhibition in Acute Myeloid Leukemia.
Tibes R, Bogenberger JM
Front Oncol, 9:1205, 12 Dec 2019
Cited by: 22 articles | PMID: 31921615 | PMCID: PMC6920180
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A novel CDK9 inhibitor increases the efficacy of venetoclax (ABT-199) in multiple models of hematologic malignancies.
Phillips DC, Jin S, Gregory GP, Zhang Q, Xue J, Zhao X, Chen J, Tong Y, Zhang H, Smith M, Tahir SK, Clark RF, Penning TD, Devlin JR, Shortt J, Hsi ED, Albert DH, Konopleva M, Johnstone RW, [...] Souers AJ
Leukemia, 34(6):1646-1657, 11 Dec 2019
Cited by: 42 articles | PMID: 31827241 | PMCID: PMC7266741
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