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NUP98 oncofusions in myeloid malignancies: An update on molecular mechanisms and therapeutic opportunities.
Rasouli M, Troester S, Grebien F, Goemans BF, Zwaan CM, Heidenreich O
Hemasphere, 8(9):e70013, 25 Sep 2024
Cited by: 0 articles | PMID: 39323480 | PMCID: PMC11423334
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Prognostic importance of NUP98-rearrangements in acute myeloid leukemia: A systematic review and meta-analysis.
Sheikhi M, Siyadat P, Rostami M, Sadeghian MH, Zahiri E, Ghorbani M, Ayatollahi H, Ayatollahi A, Hemmatan Attarbashi R, Khoshnegah Z
Caspian J Intern Med, 15(4):579-588, 30 Aug 2024
Cited by: 0 articles | PMID: 39359452 | PMCID: PMC11444110
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Myeloid/lymphoid neoplasms with eosinophilia and FGFR1 rearrangement t(8;13)(p11;q12): A case report and literature review.
Guo YJ, Ma MX, Tian T, Zhang JN, Guo XN, Qiao S
Oncol Lett, 28(4):468, 31 Jul 2024
Cited by: 0 articles | PMID: 39119236 | PMCID: PMC11306990
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NUP98-BPTF promotes oncogenic transformation through PIM1 upregulation.
Noura M, Tomita S, Yasuda T, Tsuzuki S, Kiyoi H, Hayakawa F
Cancer Med, 13(13):e7445, 01 Jul 2024
Cited by: 0 articles | PMID: 38940430
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Acute myeloid leukemia with rare recurring translocations-an overview of the entities included in the international consensus classification.
Rørvik SD, Torkildsen S, Bruserud Ø, Tvedt THA
Ann Hematol, 103(4):1103-1119, 06 Mar 2024
Cited by: 1 article | PMID: 38443661 | PMCID: PMC10940453
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Allogeneic stem cell transplantation can prolong the survival of patients with NUP98-rearranged acute myeloid leukemia.
Shen Y, Zhang T, Zhang L, Zhen S, Chen Z, Zhang R, Yang D, Wei J, He Y, Jiang E, Feng S
Bone Marrow Transplant, 58(10):1149-1151, 07 Jul 2023
Cited by: 2 articles | PMID: 37420010
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The 8p11 myeloproliferative syndrome: Genotypic and phenotypic classification and targeted therapy.
Li T, Zhang G, Zhang X, Lin H, Liu Q
Front Oncol, 12:1015792, 03 Nov 2022
Cited by: 4 articles | PMID: 36408177 | PMCID: PMC9669583
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RAS activation induces synthetic lethality of MEK inhibition with mitochondrial oxidative metabolism in acute myeloid leukemia.
Decroocq J, Birsen R, Montersino C, Chaskar P, Mano J, Poulain L, Friedrich C, Alary AS, Guermouche H, Sahal A, Fouquet G, Gotanègre M, Simonetta F, Mouche S, Gestraud P, Lescure A, Del Nery E, Bosc C, Grenier A, [...] Tamburini J
Leukemia, 36(5):1237-1252, 30 Mar 2022
Cited by: 12 articles | PMID: 35354920 | PMCID: PMC9061298
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Phase Separation Mediates NUP98 Fusion Oncoprotein Leukemic Transformation.
Chandra B, Michmerhuizen NL, Shirnekhi HK, Tripathi S, Pioso BJ, Baggett DW, Mitrea DM, Iacobucci I, White MR, Chen J, Park CG, Wu H, Pounds S, Medyukhina A, Khairy K, Gao Q, Qu C, Abdelhamed S, Gorman SD, [...] Kriwacki RW
Cancer Discov, 12(4):1152-1169, 01 Apr 2022
Cited by: 70 articles | PMID: 34903620 | PMCID: PMC8983581
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Clinico-biological features of T-cell acute lymphoblastic leukemia with fusion proteins.
Steimlé T, Dourthe ME, Alcantara M, Touzart A, Simonin M, Mondesir J, Lhermitte L, Bond J, Graux C, Grardel N, Cayuela JM, Arnoux I, Gandemer V, Balsat M, Vey N, Macintyre E, Ifrah N, Dombret H, Petit A, [...] Asnafi V
Blood Cancer J, 12(1):14, 26 Jan 2022
Cited by: 10 articles | PMID: 35082269 | PMCID: PMC8791998
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Biomolecular condensation of NUP98 fusion proteins drives leukemogenic gene expression.
Terlecki-Zaniewicz S, Humer T, Eder T, Schmoellerl J, Heyes E, Manhart G, Kuchynka N, Parapatics K, Liberante FG, Müller AC, Tomazou EM, Grebien F
Nat Struct Mol Biol, 28(2):190-201, 21 Jan 2021
Cited by: 50 articles | PMID: 33479542 | PMCID: PMC7116736
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CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia.
Schmoellerl J, Barbosa IAM, Eder T, Brandstoetter T, Schmidt L, Maurer B, Troester S, Pham HTT, Sagarajit M, Ebner J, Manhart G, Aslan E, Terlecki-Zaniewicz S, Van der Veen C, Hoermann G, Duployez N, Petit A, Lapillonne H, Puissant A, [...] Grebien F
Blood, 136(4):387-400, 01 Jul 2020
Cited by: 39 articles | PMID: 32344427 | PMCID: PMC7115844
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Mechanistic insights and potential therapeutic approaches for NUP98-rearranged hematologic malignancies.
Michmerhuizen NL, Klco JM, Mullighan CG
Blood, 136(20):2275-2289, 01 Nov 2020
Cited by: 51 articles | PMID: 32766874 | PMCID: PMC7702474
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[Myelodysplastic syndrome with t(7;11)(p15;p15)/NHA9: 2 cases report and lectures review].
Li YL, Wu CY, Dong XY, Huang ZF, Li ZB, Zhang L, Xi FL, Zhang L, Zhu ZM
Zhonghua Xue Ye Xue Za Zhi, 41(5):425-427, 01 May 2020
Cited by: 0 articles | PMID: 32536142 | PMCID: PMC7342064
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RARG Gene Dysregulation in Acute Myeloid Leukemia.
Conserva MR, Redavid I, Anelli L, Zagaria A, Specchia G, Albano F
Front Mol Biosci, 6:114, 24 Oct 2019
Cited by: 14 articles | PMID: 31709264 | PMCID: PMC6822255
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The Pleiotropic Role of Retinoic Acid/Retinoic Acid Receptors Signaling: From Vitamin A Metabolism to Gene Rearrangements in Acute Promyelocytic Leukemia.
Conserva MR, Anelli L, Zagaria A, Specchia G, Albano F
Int J Mol Sci, 20(12):E2921, 14 Jun 2019
Cited by: 13 articles | PMID: 31207999 | PMCID: PMC6627493
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Transcriptome analysis offers a comprehensive illustration of the genetic background of pediatric acute myeloid leukemia.
Shiba N, Yoshida K, Hara Y, Yamato G, Shiraishi Y, Matsuo H, Okuno Y, Chiba K, Tanaka H, Kaburagi T, Takeuchi M, Ohki K, Sanada M, Okubo J, Tomizawa D, Taki T, Shimada A, Sotomatsu M, Horibe K, [...] Hayashi Y
Blood Adv, 3(20):3157-3169, 01 Oct 2019
Cited by: 38 articles | PMID: 31648321 | PMCID: PMC6849955
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Moving Myeloid Leukemia Drug Discovery Into the Third Dimension.
Cartledge Wolf DM, Langhans SA
Front Pediatr, 7:314, 30 Jul 2019
Cited by: 9 articles | PMID: 31417884 | PMCID: PMC6682595
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PRRX-NCOA1/2 rearrangement characterizes a distinctive fibroblastic neoplasm.
Lacambra MD, Weinreb I, Demicco EG, Chow C, Sung YS, Swanson D, To KF, Wong KC, Antonescu CR, Dickson BC
Genes Chromosomes Cancer, 58(10):705-712, 30 Apr 2019
Cited by: 6 articles | PMID: 31008539 | PMCID: PMC7104602
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Long-term molecular remission in a patient with acute myeloid leukemia harboring a new NUP98-LEDGF rearrangement.
Gallego Hernanz MP, Torregrosa Diaz JM, Sorel N, Bobin A, Dindinaud E, Bouyer S, Desmier D, Brizard F, Leleu X, Maillard N, Chomel JC
Cancer Med, 8(4):1765-1770, 07 Mar 2019
Cited by: 5 articles | PMID: 30848074 | PMCID: PMC6488106
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Chimeric NUP98-NSD1 transcripts from the cryptic t(5;11)(q35.2;p15.4) in adult de novo acute myeloid leukemia.
Kivioja JL, Lopez Martí JM, Kumar A, Kontro M, Edgren H, Parsons A, Lundán T, Wolf M, Porkka K, Heckman CA
Leuk Lymphoma, 59(3):725-732, 04 Aug 2017
Cited by: 5 articles | PMID: 28776436
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The Role of Nuclear Receptor-Binding SET Domain Family Histone Lysine Methyltransferases in Cancer.
Bennett RL, Swaroop A, Troche C, Licht JD
Cold Spring Harb Perspect Med, 7(6):a026708, 01 Jun 2017
Cited by: 90 articles | PMID: 28193767 | PMCID: PMC5453381
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Involvement of a member of the histone cluster 1 at 6p21 in NUP98-positive MDS/AML.
Di Giacomo D, Pierini V, La Starza R, Borlenghi E, Pellanera F, Lema Fernandez AG, Bellotti D, Lamorgese C, Rossi G, Mecucci C
Leuk Lymphoma, 58(11):2765-2767, 09 May 2017
Cited by: 0 articles | PMID: 28482724
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Pediatric T-cell acute lymphoblastic leukemia.
Karrman K, Johansson B
Genes Chromosomes Cancer, 56(2):89-116, 25 Oct 2016
Cited by: 70 articles | PMID: 27636224
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NUP98 is rearranged in 3.8% of pediatric AML forming a clinical and molecular homogenous group with a poor prognosis.
Struski S, Lagarde S, Bories P, Puiseux C, Prade N, Cuccuini W, Pages MP, Bidet A, Gervais C, Lafage-Pochitaloff M, Roche-Lestienne C, Barin C, Penther D, Nadal N, Radford-Weiss I, Collonge-Rame MA, Gaillard B, Mugneret F, Lefebvre C, [...] Delabesse E
Leukemia, 31(3):565-572, 03 Oct 2016
Cited by: 61 articles | PMID: 27694926
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