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Search life-sciences literature (45,103,589 articles, preprints and more)

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When less is more - a fast TurboID knock-in approach for high-sensitivity endogenous interactome mapping.
Stockhammer A, Spalt C, Klemt A, Benz LS, Harel S, Natalia V, Wiench L, Freund C, Kuropka B, Bottanelli F
J Cell Sci, 137(16):jcs261952, 28 Aug 2024
Cited by: 0 articles | PMID: 39056144 | PMCID: PMC11385326
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Dual Chemotherapeutic Loading in Oxalate Transferrin-Conjugated Polymersomes Incorporated into Chitosan Hydrogels for Site-Specific Targeting of Melanoma Cells.
Aranha MC, Alencar LMR, Souto EB, Kamei DT, Lopes AM
Pharmaceuticals (Basel), 17(9):1177, 06 Sep 2024
Cited by: 0 articles | PMID: 39338339 | PMCID: PMC11434979
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Loss of symmetric cell division of apical neural progenitors drives DENND5A-related developmental and epileptic encephalopathy.
Banks E, Francis V, Lin SJ, Kharfallah F, Fonov V, Lévesque M, Han C, Kulasekaran G, Tuznik M, Bayati A, Al-Khater R, Alkuraya FS, Argyriou L, Babaei M, Bahlo M, Bakhshoodeh B, Barr E, Bartik L, Bassiony M, [...] McPherson PS
Nat Commun, 15(1):7239, 22 Aug 2024
Cited by: 0 articles | PMID: 39174524 | PMCID: PMC11341845
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Deciphering NF-kappaB pathways in smoking-related lung carcinogenesis.
Thapa R, Moglad E, Goyal A, Bhat AA, Almalki WH, Kazmi I, Alzarea SI, Ali H, Oliver BG, MacLoughlin R, Dureja H, Singh SK, Dua K, Gupta G
EXCLI J, 23:991-1017, 19 Aug 2024
Cited by: 1 article | PMID: 39253534 | PMCID: PMC11382301
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The TRIM4 E3 ubiquitin ligase degrades TPL2 and is modulated by oncogenic KRAS.
Bansod S, Dodhiawala PB, Geng Y, Bulle A, Liu P, Li L, Townsend R, Grierson PM, Held JM, Adhikari H, Lim KH
Cell Rep, 43(9):114667, 22 Aug 2024
Cited by: 0 articles | PMID: 39178114 | PMCID: PMC11472288
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Determinants of resistance and response to melanoma therapy.
Robertson BM, Fane ME, Weeraratna AT, Rebecca VW
Nat Cancer, 5(7):964-982, 17 Jul 2024
Cited by: 1 article | PMID: 39020103
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Personalized therapy in oncology: melanoma as a paradigm for molecular-targeted treatment approaches.
Kim KB
Clin Exp Metastasis, 41(4):465-471, 27 Jun 2024
Cited by: 0 articles | PMID: 38935186
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Splice variants of CK1α and CK1α-like: Comparative analysis of subcellular localization, kinase activity, and function in the Wnt signaling pathway.
Gybeľ T, Čada Š, Klementová D, Schwalm MP, Berger BT, Šebesta M, Knapp S, Bryja V
J Biol Chem, 300(7):107407, 23 May 2024
Cited by: 0 articles | PMID: 38796065 | PMCID: PMC11255964
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De Novo Multi-Omics Pathway Analysis Designed for Prior Data Independent Inference of Cell Signaling Pathways.
Vaparanta K, Merilahti JAM, Ojala VK, Elenius K
Mol Cell Proteomics, 23(7):100780, 03 May 2024
Cited by: 0 articles | PMID: 38703893 | PMCID: PMC11259815
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RAF and MEK Inhibitors in Non-Small Cell Lung Cancer.
Adamopoulos C, Papavassiliou KA, Poulikakos PI, Papavassiliou AG
Int J Mol Sci, 25(9):4633, 24 Apr 2024
Cited by: 0 articles | PMID: 38731852 | PMCID: PMC11083651
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The effects of Aurora Kinase inhibition on thyroid cancer growth and sensitivity to MAPK-directed therapies.
Hicks HM, Nassar VL, Lund J, Rose MM, Schweppe RE
Cancer Biol Ther, 25(1):2332000, 23 Mar 2024
Cited by: 0 articles | PMID: 38521968 | PMCID: PMC10962586
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BRAF - a tumour-agnostic drug target with lineage-specific dependencies.
Hanrahan AJ, Chen Z, Rosen N, Solit DB
Nat Rev Clin Oncol, 21(3):224-247, 26 Jan 2024
Cited by: 12 articles | PMID: 38278874
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Immune checkpoint inhibitors in metastatic melanoma therapy (Review).
Shah V, Panchal V, Shah A, Vyas B, Agrawal S, Bharadwaj S
Med Int (Lond), 4(2):13, 09 Feb 2024
Cited by: 6 articles | PMID: 38410760 | PMCID: PMC10895472
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Mechanisms of Melanoma Progression and Treatment Resistance: Role of Cancer Stem-like Cells.
Al Hmada Y, Brodell RT, Kharouf N, Flanagan TW, Alamodi AA, Hassan SY, Shalaby H, Hassan SL, Haikel Y, Megahed M, Santourlidis S, Hassan M
Cancers (Basel), 16(2):470, 22 Jan 2024
Cited by: 4 articles | PMID: 38275910 | PMCID: PMC10814963
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Targeting CRAF kinase in anti-cancer therapy: progress and opportunities.
Wang P, Laster K, Jia X, Dong Z, Liu K
Mol Cancer, 22(1):208, 18 Dec 2023
Cited by: 0 articles | PMID: 38111008 | PMCID: PMC10726672
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Pharmacological approaches to understanding protein kinase signaling networks.
Stephenson EH, Higgins JMG
Front Pharmacol, 14:1310135, 14 Dec 2023
Cited by: 2 articles | PMID: 38164473 | PMCID: PMC10757940
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Targeting the RAS/RAF/MAPK pathway for cancer therapy: from mechanism to clinical studies.
Bahar ME, Kim HJ, Kim DR
Signal Transduct Target Ther, 8(1):455, 18 Dec 2023
Cited by: 56 articles | PMID: 38105263 | PMCID: PMC10725898
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The Targeted Degradation of BRAF V600E Reveals the Mechanisms of Resistance to BRAF-Targeted Treatments in Colorectal Cancer Cells.
Chapdelaine AG, Ku GC, Sun G, Ayrapetov MK
Cancers (Basel), 15(24):5805, 12 Dec 2023
Cited by: 1 article | PMID: 38136350 | PMCID: PMC10741866
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Controlling the interaction between CaMKII and Calmodulin with a photocrosslinking unnatural amino acid.
Lučić I, Jiang PL, Franz A, Bursztyn Y, Liu F, Plested AJR
Protein Sci, 32(11):e4798, 01 Nov 2023
Cited by: 1 article | PMID: 37784242 | PMCID: PMC10588329
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Sequence basis for selectivity of ephrin-B2 ligand for Eph receptors and pathogenic henipavirus G glycoproteins.
Narayanan KK, Amaya M, Tsang N, Yin R, Jays A, Broder CC, Shukla D, Procko E
J Virol, 97(11):e0062123, 16 Oct 2023
Cited by: 2 articles | PMID: 37931130 | PMCID: PMC10688352
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Tumor Cell Resistance to the Inhibition of BRAF and MEK1/2.
Chen W, Park JI
Int J Mol Sci, 24(19):14837, 02 Oct 2023
Cited by: 3 articles | PMID: 37834284 | PMCID: PMC10573597
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Twenty years of research in melanoma therapy-From "nothing works" to cures: A personal account.
Herlyn M, Villanueva J
Pigment Cell Melanoma Res, 36(6):583-587, 19 Sep 2023
Cited by: 0 articles | PMID: 37726985 | PMCID: PMC11187729
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Synthetic Heterodimers of Type III Interferon Receptors Require TYK2 for STAT Activation.
Mesev EV, Guare EG, Ploss A, Toettcher JE
J Interferon Cytokine Res, 43(9):414-426, 01 Sep 2023
Cited by: 2 articles | PMID: 37725008 | PMCID: PMC10517332
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A novel germline hyperactivating JAK2 mutation L604F.
Dvořáček L, Marková J, Holoubek A, Grebeňová D, Kundrát D, Kuželová K, Schwarz J
Ann Hematol, 102(10):2725-2734, 28 Aug 2023
Cited by: 0 articles | PMID: 37639050 | PMCID: PMC10492870
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Certain heterozygous variants in the kinase domain of the serine/threonine kinase NEK8 can cause an autosomal dominant form of polycystic kidney disease.
Claus LR, Chen C, Stallworth J, Turner JL, Slaats GG, Hawks AL, Mabillard H, Senum SR, Srikanth S, Flanagan-Steet H, Louie RJ, Silver J, Lerner-Ellis J, Morel C, Mighton C, Sleutels F, van Slegtenhorst M, van Ham T, Brooks AS, [...] Steet R
Kidney Int, 104(5):995-1007, 19 Aug 2023
Cited by: 5 articles | PMID: 37598857 | PMCID: PMC10592035
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