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Search life-sciences literature (45,103,589 articles, preprints and more)

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Reduced uterine perfusion pressure as a model for preeclampsia and fetal growth restriction in murine: a systematic review and meta-analysis.
van Kammen CM, Taal SEL, Wever KE, Granger JP, Lely AT, Terstappen F
Am J Physiol Heart Circ Physiol, 327(1):H89-H107, 17 May 2024
Cited by: 1 article | PMID: 38758122 | PMCID: PMC11380978
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Increased uterine arterial tone, stiffness and remodeling with augmented matrix metalloproteinase-1 and -7 in uteroplacental ischemia-induced hypertensive pregnancy.
Lin C, Mazzuca MQ, Khalil RA
Biochem Pharmacol, 228:116227, 19 Apr 2024
Cited by: 0 articles | PMID: 38643908
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Regulation of vascular angiotensin II type 1 and type 2 receptor and angiotensin-(1-7)/MasR signaling in normal and hypertensive pregnancy.
Clark CR, Khalil RA
Biochem Pharmacol, 220:115963, 05 Dec 2023
Cited by: 4 articles | PMID: 38061417
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Gestational intermittent hypoxia induces endothelial dysfunction and hypertension in pregnant rats: role of endothelin type B receptor†.
Song R, Yadav P, Dangudubiyyam SV, Hofmann A, Mishra JS, Kumar S
Biol Reprod, 110(1):185-197, 01 Jan 2024
Cited by: 2 articles | PMID: 37823770 | PMCID: PMC11484499
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MicroRNA-195-5p Attenuates Pregnancy-Induced Hypertension by Inhibiting Oxidative Stress via OTX1/MAPK Signaling Pathway.
Liu L, Yao C, Song Z
Biochem Genet, 62(5):3642-3657, 04 Jan 2024
Cited by: 1 article | PMID: 38177835
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Increased Ca²⁺-dependent intrinsic tone and arterial stiffness in mesenteric microvessels of hypertensive pregnant rats.
Mazzuca MQ, Buyukcelebi K, Lin C, Khalil RA
Biochem Pharmacol, 208:115353, 24 Nov 2022
Cited by: 3 articles | PMID: 36435203 | PMCID: PMC9877182
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Role of microRNAs in trophoblast invasion and spiral artery remodeling: Implications for preeclampsia.
Hayder H, Shan Y, Chen Y, O'Brien JA, Peng C
Front Cell Dev Biol, 10:995462, 03 Oct 2022
Cited by: 6 articles | PMID: 36263015 | PMCID: PMC9575991
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PAD4 silencing inhibits inflammation whilst promoting trophoblast cell invasion and migration by inactivating the NEMO/NF-κB pathway.
Zeng M, Xu M, Li X, Li J, Liu Y
Exp Ther Med, 24(3):568, 12 Jul 2022
Cited by: 3 articles | PMID: 35978928 | PMCID: PMC9366263
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Uteroplacental Circulation in Normal Pregnancy and Preeclampsia: Functional Adaptation and Maladaptation.
Hu X, Zhang L
Int J Mol Sci, 22(16):8622, 11 Aug 2021
Cited by: 18 articles | PMID: 34445328 | PMCID: PMC8395300
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TNFα blockade reverses vascular and uteroplacental matrix metalloproteinases imbalance and collagen accumulation in hypertensive pregnant rats.
Ren Z, Cui N, Zhu M, Khalil RA
Biochem Pharmacol, 193:114790, 01 Oct 2021
Cited by: 5 articles | PMID: 34600915 | PMCID: PMC8606001
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Chemerin promotes the pathogenesis of preeclampsia by activating CMKLR1/p-Akt/CEBPɑ axis and inducing M1 macrophage polarization.
Ji ZS, Jiang H, Xie Y, Wei QP, Yin XF, Ye JH, Quan XZ, Lan YL, Zhao M, Tian XL, Zhang YJ, Yang XZ
Cell Biol Toxicol, 38(4):611-628, 16 Aug 2021
Cited by: 16 articles | PMID: 34398343
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Carbonic anhydrase inhibition improves pulmonary artery reactivity and nitric oxide-mediated relaxation in sugen-hypoxia model of pulmonary hypertension.
Christou H, Michael Z, Spyropoulos F, Chen Y, Rong D, Khalil RA
Am J Physiol Regul Integr Comp Physiol, 320(6):R835-R850, 07 Apr 2021
Cited by: 3 articles | PMID: 33826428 | PMCID: PMC8285620
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Vascular mechanisms and molecular targets in hypertensive pregnancy and preeclampsia.
Qu H, Khalil RA
Am J Physiol Heart Circ Physiol, 319(3):H661-H681, 07 Aug 2020
Cited by: 53 articles | PMID: 32762557 | PMCID: PMC7509272
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Reductions of Circulating Nitric Oxide are Followed by Hypertension during Pregnancy and Increased Activity of Matrix Metalloproteinases-2 and -9 in Rats.
Nascimento RA, Possomato-Vieira JS, Bonacio GF, Rizzi E, Dias-Junior CA
Cells, 8(11):E1402, 07 Nov 2019
Cited by: 9 articles | PMID: 31703340 | PMCID: PMC6912623
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Microvascular Disease and Small-Vessel Disease: The Nexus of Multiple Diseases of Women.
Patel H, Aggarwal NT, Rao A, Bryant E, Sanghani RM, Byrnes M, Kalra D, Dairaghi L, Braun L, Gabriel S, Volgman AS
J Womens Health (Larchmt), 29(6):770-779, 19 Feb 2020
Cited by: 25 articles | PMID: 32074468 | PMCID: PMC7307673
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Decreased uterine vascularization and uterine arterial expansive remodeling with reduced matrix metalloproteinase-2 and -9 in hypertensive pregnancy.
Lin C, He H, Cui N, Ren Z, Zhu M, Khalil RA
Am J Physiol Heart Circ Physiol, 318(1):H165-H180, 13 Dec 2019
Cited by: 22 articles | PMID: 31834839 | PMCID: PMC6985805
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HIF-1α regulates angiogenesis via Notch1/STAT3/ETBR pathway in trophoblastic cells.
Yu N, Wu JL, Xiao J, Fan L, Chen SH, Li W
Cell Cycle, 18(24):3502-3512, 14 Nov 2019
Cited by: 25 articles | PMID: 31724455 | PMCID: PMC6927703
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Sulodexide promotes arterial relaxation via endothelium-dependent nitric oxide-mediated pathway.
Raffetto JD, Calanni F, Mattana P, Khalil RA
Biochem Pharmacol, 166:347-356, 20 Apr 2019
Cited by: 14 articles | PMID: 31014752 | PMCID: PMC6602837
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Placental Origins of Preeclampsia: Potential Therapeutic Targets.
Wu JL, Jia J, He MZ, Zeng Y, Zhang JY, Shi EJ, Lai SY, Zhou X, Sharifu LM, Feng L
Curr Med Sci, 39(2):190-195, 23 Apr 2019
Cited by: 5 articles | PMID: 31016509
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Interactions between the complement and endothelin systems in normal pregnancy and following placental ischemia.
Regal JF, Lund JM, Wing CR, Root KM, McCutcheon L, Bemis LT, Gilbert JS, Fleming SD
Mol Immunol, 114:10-18, 18 Jul 2019
Cited by: 6 articles | PMID: 31326653 | PMCID: PMC6774867
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Characterisation of the Selective Reduced Uteroplacental Perfusion (sRUPP) Model of Preeclampsia.
Morton JS, Levasseur J, Ganguly E, Quon A, Kirschenman R, Dyck JRB, Fraser GM, Davidge ST
Sci Rep, 9(1):9565, 02 Jul 2019
Cited by: 21 articles | PMID: 31266978 | PMCID: PMC6606748
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Resveratrol promotes trophoblast invasion in pre-eclampsia by inducing epithelial-mesenchymal transition.
Zou Y, Li S, Wu D, Xu Y, Wang S, Jiang Y, Liu F, Jiang Z, Qu H, Yu X, Wang X, Wang Y, Sun L
J Cell Mol Med, 23(4):2702-2710, 01 Feb 2019
Cited by: 26 articles | PMID: 30710417 | PMCID: PMC6433653
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Residual vascular dysfunction in women with a history of preeclampsia.
Stanhewicz AE
Am J Physiol Regul Integr Comp Physiol, 315(6):R1062-R1071, 22 Aug 2018
Cited by: 15 articles | PMID: 30133302 | PMCID: PMC6734059
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Molecular determinants of microvascular dysfunction in hypertensive pregnancy and preeclampsia.
Yu W, Gao W, Rong D, Wu Z, Khalil RA
Microcirculation, e12508, 19 Oct 2018
Cited by: 13 articles | PMID: 30338879 | PMCID: PMC6474836
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Placental growth factor reverses decreased vascular and uteroplacental MMP-2 and MMP-9 and increased MMP-1 and MMP-7 and collagen types I and IV in hypertensive pregnancy.
Ren Z, Cui N, Zhu M, Khalil RA
Am J Physiol Heart Circ Physiol, 315(1):H33-H47, 23 Mar 2018
Cited by: 21 articles | PMID: 29569955 | PMCID: PMC6087780
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