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Search life-sciences literature (45,103,589 articles, preprints and more)

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Porcine NLRC3 specially binds short dsDNA to regulate cGAS activation.
Li M, Zhu C, Yuan Y, Huang X, Wu L, Wu J, Yin H, Chai L, Qu W, Yan Y, Li P, Li X
iScience, 27(11):111145, 10 Oct 2024
Cited by: 0 articles | PMID: 39524340 | PMCID: PMC11544074
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A bacterial immunity protein directly senses two disparate phage proteins.
Zhang T, Cepauskas A, Nadieina A, Thureau A, Coppieters 't Wallant K, Martens C, Lim DC, Garcia-Pino A, Laub MT
Nature, 16 Oct 2024
Cited by: 0 articles | PMID: 39415022
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Inflammasomes at the Foundation of Inflammatory Cell Death Complexes.
Tweedell RE, Kanneganti TD
J Immunol, 213(3):247-249, 01 Aug 2024
Cited by: 0 articles | PMID: 39008793
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Blockade of IKK signaling induces RIPK1-independent apoptosis in human macrophages.
Nataraj NM, Sillas RG, Herrmann BI, Shin S, Brodsky IE
PLoS Pathog, 20(8):e1012469, 26 Aug 2024
Cited by: 1 article | PMID: 39186805 | PMCID: PMC11407650
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Pyroptosis in Skeleton Diseases: A Potential Therapeutic Target Based on Inflammatory Cell Death.
Wu Q, Du J, Bae EJ, Choi Y
Int J Mol Sci, 25(16):9068, 21 Aug 2024
Cited by: 0 articles | PMID: 39201755 | PMCID: PMC11354934
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Function and Global Regulation of Type III Secretion System and Flagella in Entomopathogenic Nematode Symbiotic Bacteria.
Huang X, Li C, Zhang K, Li K, Xie J, Peng Y, Quan M, Sun Y, Hu Y, Xia L, Hu S
Int J Mol Sci, 25(14):7579, 10 Jul 2024
Cited by: 0 articles | PMID: 39062822 | PMCID: PMC11277461
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NLRC5 senses NAD⁺ depletion, forming a PANoptosome and driving PANoptosis and inflammation.
Sundaram B, Pandian N, Kim HJ, Abdelaal HM, Mall R, Indari O, Sarkar R, Tweedell RE, Alonzo EQ, Klein J, Pruett-Miller SM, Vogel P, Kanneganti TD
Cell, 187(15):4061-4077.e17, 14 Jun 2024
Cited by: 7 articles | PMID: 38878777 | PMCID: PMC11283362
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The NLR family of innate immune and cell death sensors.
Sundaram B, Tweedell RE, Prasanth Kumar S, Kanneganti TD
Immunity, 57(4):674-699, 01 Apr 2024
Cited by: 11 articles | PMID: 38599165
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Pharmacological Analysis of NLRP3 Inflammasome Inhibitor Sodium [(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl][(1-methyl-1H-pyrazol-4-yl)({[(2S)-oxolan-2-yl]methyl})sulfamoyl]azanide in Cellular and Mouse Models of Inflammation Provides a Translational Framework.
Doedens JR, Smolak P, Nguyen M, Wescott H, Diamond C, Schooley K, Billinton A, Harrison D, Koller BH, Watt AP, Gabel CA
ACS Pharmacol Transl Sci, 7(5):1438-1456, 18 Apr 2024
Cited by: 1 article | PMID: 38751618
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Strategies of bacterial detection by inflammasomes.
Jastrab JB, Kagan JC
Cell Chem Biol, 31(5):835-850, 17 Apr 2024
Cited by: 0 articles | PMID: 38636521
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Flagellin-modulated inflammasome pathways characterize the human alveolar macrophage response to <i>Burkholderia pseudomallei</i>, a lung-tropic pathogen.
Lovelace-Macon L, Baker SM, Ducken D, Seal S, Rerolle G, Tomita D, Smith KD, Schwarz S, West TE
Infect Immun, 92(5):e0006024, 15 Apr 2024
Cited by: 0 articles | PMID: 38619302 | PMCID: PMC11075458
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The interaction of inflammasomes and gut microbiota: novel therapeutic insights.
Manshouri S, Seif F, Kamali M, Bahar MA, Mashayekh A, Molatefi R
Cell Commun Signal, 22(1):209, 02 Apr 2024
Cited by: 0 articles | PMID: 38566180 | PMCID: PMC10986108
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Role of NLRP3 in Parkinson's disease: Specific activation especially in dopaminergic neurons.
Yu J, Zhao Z, Li Y, Chen J, Huang N, Luo Y
Heliyon, 10(7):e28838, 28 Mar 2024
Cited by: 2 articles | PMID: 38596076 | PMCID: PMC11002585
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Structural basis of the human NAIP/NLRC4 inflammasome assembly and pathogen sensing.
Matico RE, Yu X, Miller R, Somani S, Ricketts MD, Kumar N, Steele RA, Medley Q, Berger S, Faustin B, Sharma S
Nat Struct Mol Biol, 31(1):82-91, 04 Jan 2024
Cited by: 2 articles | PMID: 38177670 | PMCID: PMC10803261
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The role of inflammasomes in human diseases and their potential as therapeutic targets.
Yao J, Sterling K, Wang Z, Zhang Y, Song W
Signal Transduct Target Ther, 9(1):10, 05 Jan 2024
Cited by: 15 articles | PMID: 38177104 | PMCID: PMC10766654
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NAIP/NLRC4 inflammasome participates in macrophage responses to Trypanosoma cruzi by a mechanism that relies on cathepsin-dependent caspase-1 cleavage.
Amaral MP, Cardoso FD, de Farias IS, de Souza RQ, Matteucci KC, Torrecilhas AC, Bortoluci KR
Front Immunol, 14:1282856, 06 Dec 2023
Cited by: 3 articles | PMID: 38124741 | PMCID: PMC10731265
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Structural basis for flagellin-induced NAIP5 activation.
Paidimuddala B, Cao J, Zhang L
Sci Adv, 9(49):eadi8539, 06 Dec 2023
Cited by: 2 articles | PMID: 38055825 | PMCID: PMC10699770
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Structural insights into cytokine cleavage by inflammatory caspase-4.
Devant P, Dong Y, Mintseris J, Ma W, Gygi SP, Wu H, Kagan JC
Nature, 624(7991):451-459, 22 Nov 2023
Cited by: 15 articles | PMID: 37993712
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Burkholderia pseudomallei BicA protein promotes pathogenicity in macrophages by regulating invasion, intracellular survival, and virulence.
Stockton JL, Khakhum N, Stevenson HL, Torres AG
mSphere, 8(5):e0037823, 28 Sep 2023
Cited by: 2 articles | PMID: 37768049 | PMCID: PMC10597401
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NOD-like Receptor Signaling Pathway in Gastrointestinal Inflammatory Diseases and Cancers.
Zhou Y, Yu S, Zhang W
Int J Mol Sci, 24(19):14511, 25 Sep 2023
Cited by: 5 articles | PMID: 37833958 | PMCID: PMC10572711
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FlgM is required to evade NLRC4-mediated host protection against flagellated Salmonella.
López-Yglesias AH, Lu CC, Lai MA, Quarles EK, Zhao X, Hajjar AM, Smith KD
Infect Immun, 91(9):e0025523, 28 Aug 2023
Cited by: 1 article | PMID: 37638725 | PMCID: PMC10501211
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Inflammasome activation and pyroptosis mediate coagulopathy and inflammation in Salmonella systemic infection.
Pandeya A, Zhang Y, Cui J, Yang L, Li J, Zhang G, Wu C, Li Z, Wei Y
Microbiol Res, 275:127460, 14 Jul 2023
Cited by: 5 articles | PMID: 37467711 | PMCID: PMC10693354
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The Achromobacter type 3 secretion system drives pyroptosis and immunopathology via independent activation of NLRC4 and NLRP3 inflammasomes.
Turton K, Parks HJ, Zarodkiewicz P, Hamad MA, Dwane R, Parau G, Ingram RJ, Coll RC, Bryant CE, Valvano MA
Cell Rep, 42(8):113012, 21 Aug 2023
Cited by: 1 article | PMID: 37598340 | PMCID: PMC7614980
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Intracellular replication of Pseudomonas aeruginosa in epithelial cells requires suppression of the caspase-4 inflammasome.
Kroken AR, Klein KA, Mitchell PS, Nieto V, Jedel EJ, Evans DJ, Fleiszig SMJ
mSphere, 8(5):e0035123, 17 Aug 2023
Cited by: 7 articles | PMID: 37589460 | PMCID: PMC10597407
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Yersinia deploys type III-secreted effectors to evade caspase-4 inflammasome activation in human cells.
Zhang J, Brodsky IE, Shin S
mBio, 14(5):e0131023, 24 Aug 2023
Cited by: 2 articles | PMID: 37615436 | PMCID: PMC10653943
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1-25 of 92 results

1 2 3 Next ...

Search life-sciences literature (45,103,589 articles, preprints and more)

Search results

Porcine NLRC3 specially binds short dsDNA to regulate cGAS activation.

A bacterial immunity protein directly senses two disparate phage proteins.

Inflammasomes at the Foundation of Inflammatory Cell Death Complexes.

Blockade of IKK signaling induces RIPK1-independent apoptosis in human macrophages.

Pyroptosis in Skeleton Diseases: A Potential Therapeutic Target Based on Inflammatory Cell Death.

Function and Global Regulation of Type III Secretion System and Flagella in Entomopathogenic Nematode Symbiotic Bacteria.

NLRC5 senses NAD⁺ depletion, forming a PANoptosome and driving PANoptosis and inflammation.

The NLR family of innate immune and cell death sensors.

Pharmacological Analysis of NLRP3 Inflammasome Inhibitor Sodium [(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl][(1-methyl-1H-pyrazol-4-yl)({[(2S)-oxolan-2-yl]methyl})sulfamoyl]azanide in Cellular and Mouse Models of Inflammation Provides a Translational Framework.

Strategies of bacterial detection by inflammasomes.

Flagellin-modulated inflammasome pathways characterize the human alveolar macrophage response to <i>Burkholderia pseudomallei</i>, a lung-tropic pathogen.

The interaction of inflammasomes and gut microbiota: novel therapeutic insights.

Role of NLRP3 in Parkinson's disease: Specific activation especially in dopaminergic neurons.

Structural basis of the human NAIP/NLRC4 inflammasome assembly and pathogen sensing.

The role of inflammasomes in human diseases and their potential as therapeutic targets.

NAIP/NLRC4 inflammasome participates in macrophage responses to Trypanosoma cruzi by a mechanism that relies on cathepsin-dependent caspase-1 cleavage.

Structural basis for flagellin-induced NAIP5 activation.

Structural insights into cytokine cleavage by inflammatory caspase-4.

Burkholderia pseudomallei BicA protein promotes pathogenicity in macrophages by regulating invasion, intracellular survival, and virulence.

NOD-like Receptor Signaling Pathway in Gastrointestinal Inflammatory Diseases and Cancers.

FlgM is required to evade NLRC4-mediated host protection against flagellated Salmonella.

Inflammasome activation and pyroptosis mediate coagulopathy and inflammation in Salmonella systemic infection.

The Achromobacter type 3 secretion system drives pyroptosis and immunopathology via independent activation of NLRC4 and NLRP3 inflammasomes.

Intracellular replication of Pseudomonas aeruginosa in epithelial cells requires suppression of the caspase-4 inflammasome.

Yersinia deploys type III-secreted effectors to evade caspase-4 inflammasome activation in human cells.

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