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Search life-sciences literature (45,104,206 articles, preprints and more)

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Discovery of a Myeloid Cell Leukemia 1 (Mcl-1) Inhibitor That Demonstrates Potent In Vivo Activities in Mouse Models of Hematological and Solid Tumors.
Tarr JC, Salovich JM, Aichinger M, Jeon K, Veerasamy N, Sensintaffar JL, Arnhof H, Samwer M, Christov PP, Kim K, Wunberg T, Schweifer N, Trapani F, Arnold A, Martin F, Zhao B, Miriyala N, Sgubin D, Fogarty S, [...] Fesik SW
J Med Chem, 67(16):14370-14393, 05 Aug 2024
Cited by: 1 article | PMID: 39102508 | PMCID: PMC11345828
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Genetic screening for anticancer genes highlights FBLN5 as a synthetic lethal partner of MYC.
Masood M, Ding Q, Cawte AD, Rueda DS, Grimm SW, Yagüe E, El-Bahrawy M
Cell Commun Signal, 21(1):295, 20 Oct 2023
Cited by: 0 articles | PMID: 37864183 | PMCID: PMC10588048
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Curcumin protects rats against gentamicin-induced nephrotoxicity by amelioration of oxidative stress, endoplasmic reticulum stress and apoptosis.
Laorodphun P, Cherngwelling R, Panya A, Arjinajarn P
Pharm Biol, 60(1):491-500, 01 Dec 2022
Cited by: 14 articles | PMID: 35188833 | PMCID: PMC8865128
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Structure of a Myeloid cell leukemia-1 (Mcl-1) inhibitor bound to drug site 3 of Human Serum Albumin.
Zhao B, Sensintaffar J, Bian Z, Belmar J, Lee T, Olejniczak ET, Fesik SW
Bioorg Med Chem, 25(12):3087-3092, 29 Mar 2017
Cited by: 5 articles | PMID: 28428041 | PMCID: PMC6690437
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Apoptotic activity of 5-fluorouracil in breast cancer cells transformed by low doses of ionizing α-particle radiation.
Ponce-Cusi R, Calaf GM
Int J Oncol, 48(2):774-782, 18 Dec 2015
Cited by: 14 articles | PMID: 26691280
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Increased chemosensitivity and radiosensitivity of human breast cancer cell lines treated with novel functionalized single-walled carbon nanotubes.
Jia Y, Weng Z, Wang C, Zhu M, Lu Y, Ding L, Wang Y, Cheng X, Lin Q, Wu K
Oncol Lett, 13(1):206-214, 21 Nov 2016
Cited by: 9 articles | PMID: 28123543 | PMCID: PMC5245142
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Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods.
Pelz NF, Bian Z, Zhao B, Shaw S, Tarr JC, Belmar J, Gregg C, Camper DV, Goodwin CM, Arnold AL, Sensintaffar JL, Friberg A, Rossanese OW, Lee T, Olejniczak ET, Fesik SW
J Med Chem, 59(5):2054-2066, 24 Feb 2016
Cited by: 51 articles | PMID: 26878343 | PMCID: PMC5565212
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An Arabidopsis cell growth defect factor-related protein, CRS, promotes plant senescence by increasing the production of hydrogen peroxide.
Cui MH, Ok SH, Yoo KS, Jung KW, Yoo SD, Shin JS
Plant Cell Physiol, 54(1):155-167, 04 Dec 2012
Cited by: 24 articles | PMID: 23220690
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The Rubella virus capsid is an anti-apoptotic protein that attenuates the pore-forming ability of Bax.
Ilkow CS, Goping IS, Hobman TC
PLoS Pathog, 7(2):e1001291, 17 Feb 2011
Cited by: 24 articles | PMID: 21379337 | PMCID: PMC3040668
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Deerpox virus encodes an inhibitor of apoptosis that regulates Bak and Bax.
Banadyga L, Lam SC, Okamoto T, Kvansakul M, Huang DC, Barry M
J Virol, 85(5):1922-1934, 15 Dec 2010
Cited by: 30 articles | PMID: 21159883 | PMCID: PMC3067780
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MEK-ERK-dependent multiple caspase activation by mitochondrial proapoptotic Bcl-2 family proteins is essential for heavy ion irradiation-induced glioma cell death.
Tomiyama A, Tachibana K, Suzuki K, Seino S, Sunayama J, Matsuda KI, Sato A, Matsumoto Y, Nomiya T, Nemoto K, Yamashita H, Kayama T, Ando K, Kitanaka C
Cell Death Dis, 1:e60, 29 Jul 2010
Cited by: 31 articles | PMID: 21364665 | PMCID: PMC3039836
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Cell-type specific occurrence of apoptosis in taste buds of the rat circumvallate papilla.
Ueda K, Ichimori Y, Maruyama H, Murakami Y, Fujii M, Honma S, Wakisaka S
Arch Histol Cytol, 71(1):59-67, 01 May 2008
Cited by: 12 articles | PMID: 18622094
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The fowlpox virus BCL-2 homologue, FPV039, interacts with activated Bax and a discrete subset of BH3-only proteins to inhibit apoptosis.
Banadyga L, Veugelers K, Campbell S, Barry M
J Virol, 83(14):7085-7098, 13 May 2009
Cited by: 31 articles | PMID: 19439472 | PMCID: PMC2704773
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Study of the impact of liver transplantation on the outcome of intestinal grafts in children.
Jugie M, Canioni D, Le Bihan C, Sarnacki S, Revillon Y, Jan D, Lacaille F, Cerf-Bensussan N, Goulet O, Brousse N, Damotte D
Transplantation, 81(7):992-997, 01 Apr 2006
Cited by: 12 articles | PMID: 16612274
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Caspase-independent necrotic cell death induced by a radiosensitizer, 8-nitrocaffeine.
Naito M, Hashimoto C, Masui S, Tsuruo T
Cancer Sci, 95(4):361-366, 01 Apr 2004
Cited by: 10 articles | PMID: 15072596
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Apoptosis induced by cryo-injury in human colorectal cancer cells is associated with mitochondrial dysfunction.
Yang WL, Addona T, Nair DG, Qi L, Ravikumar TS
Int J Cancer, 103(3):360-369, 01 Jan 2003
Cited by: 57 articles | PMID: 12471619
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The permeability transition pore triggers Bax translocation to mitochondria during neuronal apoptosis.
Precht TA, Phelps RA, Linseman DA, Butts BD, Le SS, Laessig TA, Bouchard RJ, Heidenreich KA
Cell Death Differ, 12(3):255-265, 01 Mar 2005
Cited by: 60 articles | PMID: 15637643
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Assessment of p53 gene transfer and biological activities in a clinical study of adenovirus-p53 gene therapy for recurrent ovarian cancer.
Wen SF, Mahavni V, Quijano E, Shinoda J, Grace M, Musco-Hobkinson ML, Yang TY, Chen Y, Runnenbaum I, Horowitz J, Maneval D, Hutchins B, Buller R
Cancer Gene Ther, 10(3):224-238, 01 Mar 2003
Cited by: 23 articles | PMID: 12637944
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Hepatitis C virus NS5A as a potential viral Bcl-2 homologue interacts with Bax and inhibits apoptosis in hepatocellular carcinoma.
Chung YL, Sheu ML, Yen SH
Int J Cancer, 107(1):65-73, 01 Oct 2003
Cited by: 67 articles | PMID: 12925958
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Platelet-activating factor-induced apoptosis is blocked by Bcl-2 in rat intestinal epithelial cells.
Lu J, Caplan MS, Saraf AP, Li D, Adler L, Liu X, Jilling T
Am J Physiol Gastrointest Liver Physiol, 286(2):G340-50, 25 Sep 2003
Cited by: 14 articles | PMID: 14512286
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Ginsenoside Rh2 induces apoptosis via activation of caspase-1 and -3 and up-regulation of Bax in human neuroblastoma.
Kim YS, Jin SH
Arch Pharm Res, 27(8):834-839, 01 Aug 2004
Cited by: 27 articles | PMID: 15460444
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Temporal characterisation of pro- and anti-apoptotic mechanisms following diffuse traumatic brain injury in rats.
Cernak I, Chapman SM, Hamlin GP, Vink R
J Clin Neurosci, 9(5):565-572, 01 Sep 2002
Cited by: 28 articles | PMID: 12383417
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Mechanisms underlying hypoxia-induced neuronal apoptosis.
Banasiak KJ, Xia Y, Haddad GG
Prog Neurobiol, 62(3):215-249, 01 Oct 2000
Cited by: 170 articles | PMID: 10840148
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Adenovirus-mediated transfer of p53 augments hyperthermia-induced apoptosis in U251 glioma cells.
Okamoto K, Shinoura N, Egawa N, Asai A, Kirino T, Shibasaki F, Shitara N
Int J Radiat Oncol Biol Phys, 50(2):525-531, 01 Jun 2001
Cited by: 10 articles | PMID: 11380242
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Bovine herpesvirus 1 glycoprotein G is required for prevention of apoptosis and efficient viral growth in rabbit kidney cells.
Nakamichi K, Kuroki D, Matsumoto Y, Otsuka H
Virology, 279(2):488-498, 01 Jan 2001
Cited by: 11 articles | PMID: 11162805
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1-25 of 35 results

1 2

Search life-sciences literature (45,104,206 articles, preprints and more)

Search results

Discovery of a Myeloid Cell Leukemia 1 (Mcl-1) Inhibitor That Demonstrates Potent In Vivo Activities in Mouse Models of Hematological and Solid Tumors.

Genetic screening for anticancer genes highlights FBLN5 as a synthetic lethal partner of MYC.

Curcumin protects rats against gentamicin-induced nephrotoxicity by amelioration of oxidative stress, endoplasmic reticulum stress and apoptosis.

Structure of a Myeloid cell leukemia-1 (Mcl-1) inhibitor bound to drug site 3 of Human Serum Albumin.

Apoptotic activity of 5-fluorouracil in breast cancer cells transformed by low doses of ionizing α-particle radiation.

Increased chemosensitivity and radiosensitivity of human breast cancer cell lines treated with novel functionalized single-walled carbon nanotubes.

Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods.

An Arabidopsis cell growth defect factor-related protein, CRS, promotes plant senescence by increasing the production of hydrogen peroxide.

The Rubella virus capsid is an anti-apoptotic protein that attenuates the pore-forming ability of Bax.

Deerpox virus encodes an inhibitor of apoptosis that regulates Bak and Bax.

MEK-ERK-dependent multiple caspase activation by mitochondrial proapoptotic Bcl-2 family proteins is essential for heavy ion irradiation-induced glioma cell death.

Cell-type specific occurrence of apoptosis in taste buds of the rat circumvallate papilla.

The fowlpox virus BCL-2 homologue, FPV039, interacts with activated Bax and a discrete subset of BH3-only proteins to inhibit apoptosis.

Study of the impact of liver transplantation on the outcome of intestinal grafts in children.

Caspase-independent necrotic cell death induced by a radiosensitizer, 8-nitrocaffeine.

Apoptosis induced by cryo-injury in human colorectal cancer cells is associated with mitochondrial dysfunction.

The permeability transition pore triggers Bax translocation to mitochondria during neuronal apoptosis.

Assessment of p53 gene transfer and biological activities in a clinical study of adenovirus-p53 gene therapy for recurrent ovarian cancer.

Hepatitis C virus NS5A as a potential viral Bcl-2 homologue interacts with Bax and inhibits apoptosis in hepatocellular carcinoma.

Platelet-activating factor-induced apoptosis is blocked by Bcl-2 in rat intestinal epithelial cells.

Ginsenoside Rh2 induces apoptosis via activation of caspase-1 and -3 and up-regulation of Bax in human neuroblastoma.

Temporal characterisation of pro- and anti-apoptotic mechanisms following diffuse traumatic brain injury in rats.

Mechanisms underlying hypoxia-induced neuronal apoptosis.

Adenovirus-mediated transfer of p53 augments hyperthermia-induced apoptosis in U251 glioma cells.

Bovine herpesvirus 1 glycoprotein G is required for prevention of apoptosis and efficient viral growth in rabbit kidney cells.

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