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ATP synthase subunit alpha, mitochondrial

Summary

UniProt ID

P25705

Gene Symbol

ATP5F1A
ATP5A
ATP5A1
ATP5AL2
ATPM

Organism

Homo sapiens (human)

External Links

GlyGen: P25705
PubChem: P25705
The Human Metabolome Database: HMDBP01448
The O-GlcNAc Database: P25705
RaftProt: P25705
O-GlcNAcAtlas: P25705

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Alternative splicing
CF(1)
Cell membrane
Direct protein sequencing
Disease variant
Glycoprotein
Hydrogen ion transport
Methylation
Mitochondrion inner membrane
Phosphoprotein
Primary mitochondrial disease
Reference proteome
Transit peptide

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
negative regulation of endothelial cell proliferation
lipid metabolic process
response to muscle activity
cellular response to dexamethasone stimulus
positive regulation of blood vessel endothelial cell migration
cellular response to nitric oxide
response to ethanol
proton motive force-driven ATP synthesis
ATP biosynthetic process
proton motive force-driven mitochondrial ATP synthesis

Displaying entries **1 - 10** of 12 in total

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GO Term
extracellular exosome
mitochondrion
mitochondrial inner membrane
mitochondrial proton-transporting ATP synthase complex
mitochondrial matrix
membrane raft
proton-transporting ATP synthase complex
proton-transporting ATP synthase complex, catalytic core F(1)
mitochondrial proton-transporting ATP synthase, catalytic core
cell surface

Displaying **all 8** entries
GO Term
MHC class I protein binding
angiostatin binding
proton-transporting ATP synthase activity, rotational mechanism
ATP hydrolysis activity
ADP binding
ATP binding
protease binding
RNA binding

Annotation information from UniProt.

Sequence

MLSVRVAAAVVRALPRRAGLVSRNALGSSFIAARNFHASNTHLQKTGTAEMSSILEERILGADTSVDLEETGRVLSIGDGIARVHGLRNVQAEEMVEFSSGLKGMSLNLEPDNVGVVVFGNDKLIKEGDIVKRTGAIVDVPVGEELLGRVVDALGNAIDGKGPIGSKTRRRVGLKAPGIIPRISVREPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTSIAIDTIINQKRFNDGSDEKKKLYCIYVAIGQKRSTVAQLVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCSMGEYFRDNGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDAFGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREVAAFAQFGSDLDAATQQLLSRGVRLTELLKQGQYSPMAIEEQVAVIYAGVRGYLDKLEPSKITKFENAFLSHVVSQHQALLGTIRADGKISEQSDAKLKEIVTNFLAGFEA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	GlyTouCan ID	Source
46		G49108TO	GlyGen The O-GlcNAc Database
48		G49108TO	GlyGen The O-GlcNAc Database
76	O-linked (GlcNAc) serine; alternate		UniProt GlyGen
225		G49108TO	GlyGen The O-GlcNAc Database
383		G49108TO	GlyGen The O-GlcNAc Database
389		G49108TO	GlyGen
432		G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Cristae formation	Homo sapiens
Formation of ATP by chemiosmotic coupling	Homo sapiens
Mitochondrial protein degradation	Homo sapiens
Mitochondrial protein import	Homo sapiens

Human Protein Atlas

ENSG00000152234

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements