May 16, 2014 · Estimation of rodent acute toxicity is an important task in the safety assessment of drug candidates. Median lethal dose (LD50), a dose causing ...

Background · Results and discussion · Conclusion

May 16, 2014 · Encouraged by the promising results, we expect that our consensus LLL model of LD50 would become a useful tool for predicting acute toxicity ...

Results In this study, we reported the use of local lazy learning (LLL) methods, which could capture subtle local structure-toxicity relationships around each ...

Acute toxicity means the ability of a substance to cause adverse effects within a short period following dosing or exposure, which is usually the first step ...

Oct 6, 2024 · Bibliographic details on Estimation of acute oral toxicity in rat using local lazy learning.

Lu, Jing,et al."Estimation of acute oral toxicity in rat using local lazy learning".JOURNAL OF CHEMINFORMATICS 6(2014). 条目包含的文件. 文件名称/大小, 文献类型 ...

Encouraged by the promising results, we expect that our consensus LLL model of LD50 would become a useful tool for predicting acute toxicity. All models ...

One of the first applications of ML to hazard assessment was the prediction of acute oral toxicity in rats (LD50 values), using local lazy learning, achieving ...

Estimation of Acute Oral Toxicity in Rat Using Local Lazy Learning. J ... Accurate Prediction of Rat Oral Acute Toxicity Using Relevance Vector Machine ...