Glucose sensing neurons are defined as those which alter their action potential frequency in response to changes in interstitial glucose levels [18,25]. The effects of glucose on an individual hypothalamic neuron can be either postsynaptic (e.g., direct) or via an upstream presynaptic neuron (e.g., indirect) [18].
People also ask
What are the glucose-sensing neurons of the hypothalamus?
What is the function of the ventromedial hypothalamus?
What is the ventromedial hypothalamus glucose?
What are the glucose receptors in the hypothalamus?
This review will discuss the mechanisms by which glucose sensing neurons sense changes in interstitial glucose and explore the roles of these specialized ...
Feb 5, 2021 · Two types of glucose-sensing neurons are present in the hypothalamus: glucose-excited and glucose-inhibited neurons. Glucose-excited neurons are ...
May 26, 2022 · Our recent studies reveal that all ERα-expressing neurons in the vlVMH are able to sense glucose fluctuations, and prevent mice from severe ...
May 1, 2017 · The ventromedial hypothalamic nucleus (VMH) regulates glucose production in the liver as well as glucose uptake and utilization in peripheral ...
Approximately, 14% of rat VMH neurons are inherently sensitive to increased glucose and respond with an increase in electrical activity. These are termed ...
Aug 24, 2020 · These neurons fall into two categories, glucose-excited (GE) neurons, whose firing rate increases in response to a rise in extracellular glucose ...
Jun 1, 2023 · Low glucose activates neurons in the lateral hypothalamus through increasing NMDA-mediated glutamatergic currents (38). The cystic fibrosis ...
Insulin blunts the response of glucose-excited neurons in the ventrolateral-ventromedial hypothalamic nucleus to decreased glucose. · Biology, Medicine.
These neurons, referred to as glucose-sensing neurons, were initially discovered in the ventromedial nucleus of the hypothalamus (VMH) (Oomura et al., 1969).