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One of the key open problems in large-scale DNA sequence assembly is the correct reconstruction of sequences that contain repeats.
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We call the task of correcting this compression by separating the overlaid fragments into the distinct copies they sample, the repeat separation problem. We ...
This work presents a rigorous formulation of repeat separation in the general setting without prior knowledge of consensus sequences of repeats or their ...
Oct 24, 2015 · One of the key open problems in large-scale DNA sequence assembly is the correct reconstruction of sequences that contain repeats.
We call the task of correcting this compression by separating the overlaid fragments into the distinct copies they sample, the repeat separation problem. We ...
Dec 26, 2020 · You extract the DNA, fragment it, and then sequence the fragments into contigs, contiguous sequences. To do this, you need reads that contain ...
Nov 22, 2023 · Tandem repeats are sequences of DNA comprising of two or more nucleotides that are repeated in a contiguous, head-to-tail fashion on a chromosome.
the genome of discrete typing unit III Trypanosoma cruzi strain 231
pmc.ncbi.nlm.nih.gov › PMC5989580
In this study, we developed a computational workflow to assemble highly repetitive genomes via a combination of de novo and reference-based assembly strategies.
TL;DR: This work presents a rigorous formulation of repeat separation in the general setting without prior knowledge of consensus sequences of repeats or ...
The main problem in sequence assembly is the handling of repeats. Usually as- sembly algorithms concentrate first on the localization and assembly of stretches ...