Nov 2, 2017 · In this work, a bi-level programming method for the steady-state optimization of biochemical systems with GMA representations has been proposed.

This paper proposes a method to obtain initial model parameter values from the steady state of the S-System, thereby computing simpler and less complex ...

Steady-state optimization of biochemical systems by bi-level programming. Gongxian Xu, Yang Li · Details · Contributors · Fields of science · Bibliography ...

An indirect optimization method for biochemical systems: description of method and application to the maximization of the rate of ethanol, glycerol, and ...

As of yet, steady-state optimization in biochemical systems has been limited to a few studies in which networks of fluxes were optimized.

The first category deals with the maximization of reaction rates and steady-state fluxes. The second addresses the minimization of transition time, which yields ...

In this work we present a general (mono and multiobjective) optimization framework for the technological improvement of biochemical systems.

Dec 5, 2020 · Bilevel programming is known to be strongly NP-hard [80], and it has been proven that merely evaluating a solution for optimality is also a NP- ...

This paper proposes an improved geometric programming approach to address the optimization of biochemical systems. In the proposed method we take advantage of a ...

The first constraint is the steady state condition, the other two constraints keep the fluxes and the variables of the system within certain limits in order ...