KEGG   Homo sapiens (human): 5298
Entry
5298              CDS       T01001                                 
Symbol
PI4KB, DFNA87, NPIK, PI4K-BETA, PI4K92, PI4KBETA, PI4KIII, PI4KIIIBETA, PIK4CB
Name
(RefSeq) phosphatidylinositol 4-kinase beta
  KO
K19801  phosphatidylinositol 4-kinase B [EC:2.7.1.67]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00562  Inositol phosphate metabolism
hsa01100  Metabolic pathways
hsa04070  Phosphatidylinositol signaling system
Module
hsa_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Disease
H00604  Deafness, autosomal dominant
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    5298 (PI4KB)
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    5298 (PI4KB)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.67  1-phosphatidylinositol 4-kinase
     5298 (PI4KB)
SSDB
Motif
Pfam: PI3_PI4_kinase PI4KB-PIK1_PIK DUF4135 ABC1
Other DBs
NCBI-GeneID: 5298
NCBI-ProteinID: NP_001317650
OMIM: 602758
HGNC: 8984
Ensembl: ENSG00000143393
Pharos: Q9UBF8(Tchem)
UniProt: Q9UBF8
Structure
LinkDB
Position
1:complement(151291797..151327715)
AA seq 816 aa
MGDTVVEPAPLKPTSEPTSGPPGNNGGSLLSVITEGVGELSVIDPEVAQKACQEVLEKVK
LLHGGVAVSSRGTPLELVNGDGVDSEIRCLDDPPAQIREEEDEMGAAVASGTAKGARRRR
QNNSAKQSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLL
NMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLI
LSDELKPAHRKRELPSLSPAPDTGLSPSKRTHQRSKSDATASISLSSNLKRTASNPKVEN
EDEELSSSTESIDNSFSSPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLN
HKLPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTSVPARIPE
NRIRSTRSVENLPECGITHEQRAGSFSTVPNYDNDDEAWSVDDIGELQVELPEVHTNSCD
NISQFSVDSITSQESKEPVFIAAGDIRRRLSEQLAHTPTAFKRDPEDPSAVALKEPWQEK
VRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKI
LVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGY
CLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGG
LDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSM
TEEQLQLLVEQMVDGSMRSITTKLYDGFQYLTNGIM
NT seq 2451 nt   +upstreamnt  +downstreamnt
atgggagatacagtagtggagcctgcccccttgaagccaacttctgagcccacttctggc
ccaccagggaataatggggggtccctgctaagtgtcatcacggagggggtcggggaacta
tcagtgattgaccctgaggtggcccagaaggcctgccaggaggtgttggagaaagtcaag
cttttgcatggaggcgtggcagtctctagcagaggcaccccactggagttggtcaatggg
gatggtgtggacagtgagatccgttgcctagatgatccacctgcccagatcagggaggag
gaagatgagatgggggccgctgtggcctcaggcacagccaaaggagcaagaagacggcgg
cagaacaactcagctaaacagtcttggctgctgaggctgtttgagtcaaaactgtttgac
atctccatggccatttcatacctgtataactccaaggagcctggagtacaagcctacatt
ggcaaccggctcttctgctttcgcaacgaggacgtggacttctatctgccccagttgctt
aacatgtacatccacatggatgaggacgtgggtgatgccattaagccctacatagtccac
cgttgccgccagagcattaacttttccctccagtgtgccctgttgcttggggcctattct
tcagacatgcacatttccactcaacgacactcccgtgggaccaagctacggaagctgatc
ctctcagatgagctaaagccagctcacaggaagagggagctgccctccttgagcccggcc
cctgacacagggctgtctccctccaaaaggactcaccagcgctctaagtcagatgccact
gccagcataagtctcagcagcaacctgaaacgaacagccagcaaccctaaagtggagaat
gaggatgaggagctctcctccagcaccgagagtattgataattcattcagttcccctgtt
cgactggctcctgagagagaattcatcaagtccctgatggcgatcggcaagcggctggcc
acgctccccaccaaagagcagaaaacacagaggctgatctcagagctctccctgctcaac
cataagctccctgcccgagtctggctgcccactgctggctttgaccaccacgtggtccgt
gtaccccacacacaggctgttgtcctcaactccaaggacaaggctccctacctgatttat
gtggaagtccttgaatgtgaaaactttgacaccaccagtgtccctgcccggatccccgag
aaccgaattcggagtacgaggtccgtagaaaacttgcccgaatgtggtattacccatgag
cagcgagctggcagcttcagcactgtgcccaactatgacaacgatgatgaggcctggtcg
gtggatgacataggcgagctgcaagtggagctccccgaagtgcataccaacagctgtgac
aacatctcccagttctctgtggacagcatcaccagccaggagagcaaggagcctgtgttc
attgcagcaggggacatccgccggcgcctttcggaacagctggctcataccccgacagcc
ttcaaacgagacccagaagatccttctgcagttgctctcaaagagccctggcaggagaaa
gtacggcggatcagagagggctccccctacggccatctccccaattggcggctcctgtca
gtcattgtcaagtgtggggatgaccttcggcaagagcttctggcctttcaggtgttgaag
caactgcagtccatttgggaacaggagcgagtgcccctttggatcaagccatacaagatt
cttgtgatttcggctgatagtggcatgattgaaccagtggtcaatgctgtgtccatccat
caggtgaagaaacagtcacagctctccttgctcgattacttcctacaggagcacggcagt
tacaccactgaggcattcctcagtgcacagcgcaattttgtgcaaagttgtgctgggtac
tgcttggtctgctacctgctgcaagtcaaggacagacacaatgggaatatccttttggac
gcagaaggccacatcatccacatcgactttggcttcatcctctccagctcaccccgaaat
ctgggctttgagacgtcagcctttaagctgaccacagagtttgtggatgtgatgggcggc
ctggatggcgacatgttcaactactataagatgctgatgctgcaagggctgattgccgct
cggaaacacatggacaaggtggtgcagatcgtggagatcatgcagcaaggttctcagctt
ccttgcttccatggctccagcaccattcgaaacctcaaagagaggttccacatgagcatg
actgaggagcagctgcagctgctggtggagcagatggtggatggcagtatgcggtctatc
accaccaaactctatgacggcttccagtacctcaccaacggcatcatgtga

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