U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Complete cleft hard palate

MedGen UID:
1674652
•Concept ID:
C5190925
•
Congenital Abnormality
Synonym: Complete cleft of hard palate
SNOMED CT: Complete cleft of hard palate (783400002)
 
HPO: HP:5201003

Definition

Cleft hard palate in which the cleft goes through the entire length of the hard palate, ie. from the incisor foramen to the anterior border of the soft palate. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVComplete cleft hard palate

Professional guidelines

PubMed

Newborn hearing screening on infants at risk.
Ohl C, Dornier L, Czajka C, Chobaut JC, Tavernier L
Int J Pediatr Otorhinolaryngol 2009 Dec;73(12):1691-5. Epub 2009 Sep 30 doi: 10.1016/j.ijporl.2009.08.027. PMID: 19796829
Improved primary surgical and dental treatment of clefts.
Millard DR Jr, Latham RA
Plast Reconstr Surg 1990 Nov;86(5):856-71. doi: 10.1097/00006534-199011000-00006. PMID: 2236311
Management and timing of cleft palate fistula repair.
Schultz RC
Plast Reconstr Surg 1986 Dec;78(6):739-47. doi: 10.1097/00006534-198678060-00004. PMID: 3538077

Recent clinical studies

Etiology

A Meta-Analysis of Palatal Repair Timing.
Wlodarczyk JR, Brannon B, Munabi NCO, Wolfswinkel EM, Nagengast ES, Yao CA, Magee W 3rd
J Craniofac Surg 2021 Mar-Apr 01;32(2):647-651. doi: 10.1097/SCS.0000000000007029. PMID: 33705001
Speech and Audiology Outcomes After Single-Stage Versus Early 2-Stage Cleft Palate Repair.
Crowley JS, Friesen TL, Gabriel RA, Hsieh S, Wacenske A, Deal D, Tsai C, Lance S, Gosman AA
Ann Plast Surg 2021 May 1;86(5S Suppl 3):S360-S366. doi: 10.1097/SAP.0000000000002747. PMID: 33559999
Profile of Cleft Lip and Cleft Palate at a Public Hospital in Southern India.
Prabakaran S, Thilagam KK, Reddy GMM
Indian Pediatr 2019 Sep 15;56(9):753-755. PMID: 31638008
Unilateral Cleft Lip and Palate Surgical Protocols and Facial Growth Outcomes.
Pereira RMR, Siqueira N, Costa E, Vale DD, Alonso N
J Craniofac Surg 2018 Sep;29(6):1562-1568. doi: 10.1097/SCS.0000000000004810. PMID: 30373095
An uncommon cleft subtype of unilateral cleft lip and palate.
Yamanishi T, Kobayashi C, Tsujimoto I, Koizumi H, Miya S, Yokota Y, Okamoto R, Iida S, Aikawa T, Kohara H, Nishio J, Kogo M
J Dent Res 2008 Feb;87(2):164-8. doi: 10.1177/154405910808700212. PMID: 18218844

Diagnosis

Speech and Audiology Outcomes After Single-Stage Versus Early 2-Stage Cleft Palate Repair.
Crowley JS, Friesen TL, Gabriel RA, Hsieh S, Wacenske A, Deal D, Tsai C, Lance S, Gosman AA
Ann Plast Surg 2021 May 1;86(5S Suppl 3):S360-S366. doi: 10.1097/SAP.0000000000002747. PMID: 33559999
Profile of Cleft Lip and Cleft Palate at a Public Hospital in Southern India.
Prabakaran S, Thilagam KK, Reddy GMM
Indian Pediatr 2019 Sep 15;56(9):753-755. PMID: 31638008
Unilateral Cleft Lip and Palate Surgical Protocols and Facial Growth Outcomes.
Pereira RMR, Siqueira N, Costa E, Vale DD, Alonso N
J Craniofac Surg 2018 Sep;29(6):1562-1568. doi: 10.1097/SCS.0000000000004810. PMID: 30373095
A Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 1. Planning and management.
Semb G, Enemark H, Friede H, Paulin G, Lilja J, Rautio J, Andersen M, Åbyholm F, Lohmander A, Shaw W, Mølsted K, Heliövaara A, Bolund S, Hukki J, Vindenes H, Davenport P, Arctander K, Larson O, Berggren A, Whitby D, Leonard A, Neovius E, Elander A, Willadsen E, Bannister RP, Bradbury E, Henningsson G, Persson C, Eyres P, Emborg B, Kisling-Møller M, Küseler A, Granhof Black B, Schöps A, Bau A, Boers M, Andersen HS, Jeppesen K, Marxen D, Paaso M, Hölttä E, Alaluusua S, Turunen L, Humerinta K, Elfving-Little U, Tørdal IB, Kjøll L, Aukner R, Hide Ø, Feragen KB, Rønning E, Skaare P, Brinck E, Semmingsen AM, Lindberg N, Bowden M, Davies J, Mooney J, Bellardie H, Schofield N, Nyberg J, Lundberg M, Karsten AL, Larson M, Holmefjord A, Reisæter S, Pedersen NH, Rasmussen T, Tindlund R, Sæle P, Blomhoff R, Jacobsen G, Havstam C, Rizell S, Enocson L, Hagberg C, Najar Chalien M, Paganini A, Lundeborg I, Marcusson A, Mjönes AB, Gustavsson A, Hayden C, McAleer E, Slevan E, Gregg T, Worthington H
J Plast Surg Hand Surg 2017 Feb;51(1):2-13. doi: 10.1080/2000656X.2016.1263202. PMID: 28218559
Bony defect of palate and vomer in submucous cleft palate patients.
Ren S, Ma L, Zhou X, Sun Z
Int J Oral Maxillofac Surg 2015 Jan;44(1):63-6. Epub 2014 Oct 23 doi: 10.1016/j.ijom.2014.09.001. PMID: 25442739

Therapy

Speech of Patients With Unilateral Complete Cleft Lip and Palate: Comparison of Three Different Surgical Protocols for Primary Repair.
Ahti V, Alaluusua S, Rautio J, Leikola J, Hukki J, Saarikko A
J Craniofac Surg 2020 May/Jun;31(3):e291-e296. doi: 10.1097/SCS.0000000000006242. PMID: 32068730
Unilateral Cleft Lip and Palate Surgical Protocols and Facial Growth Outcomes.
Pereira RMR, Siqueira N, Costa E, Vale DD, Alonso N
J Craniofac Surg 2018 Sep;29(6):1562-1568. doi: 10.1097/SCS.0000000000004810. PMID: 30373095
Closure of fistula of the hard palate with two layers of mucoperiosteum.
Abdel-Aziz M, Kamel A, Fawaz M, Rezk I, Kamel M
Int J Pediatr Otorhinolaryngol 2018 Jan;104:43-46. Epub 2017 Oct 31 doi: 10.1016/j.ijporl.2017.10.037. PMID: 29287878
Treatment outcomes of pre-surgical infant orthopedics in patients with non-syndromic cleft lip and/or palate: A systematic review and meta-analysis of randomized controlled trials.
Hosseini HR, Kaklamanos EG, Athanasiou AE
PLoS One 2017;12(7):e0181768. Epub 2017 Jul 24 doi: 10.1371/journal.pone.0181768. PMID: 28742129Free PMC Article
A Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 1. Planning and management.
Semb G, Enemark H, Friede H, Paulin G, Lilja J, Rautio J, Andersen M, Åbyholm F, Lohmander A, Shaw W, Mølsted K, Heliövaara A, Bolund S, Hukki J, Vindenes H, Davenport P, Arctander K, Larson O, Berggren A, Whitby D, Leonard A, Neovius E, Elander A, Willadsen E, Bannister RP, Bradbury E, Henningsson G, Persson C, Eyres P, Emborg B, Kisling-Møller M, Küseler A, Granhof Black B, Schöps A, Bau A, Boers M, Andersen HS, Jeppesen K, Marxen D, Paaso M, Hölttä E, Alaluusua S, Turunen L, Humerinta K, Elfving-Little U, Tørdal IB, Kjøll L, Aukner R, Hide Ø, Feragen KB, Rønning E, Skaare P, Brinck E, Semmingsen AM, Lindberg N, Bowden M, Davies J, Mooney J, Bellardie H, Schofield N, Nyberg J, Lundberg M, Karsten AL, Larson M, Holmefjord A, Reisæter S, Pedersen NH, Rasmussen T, Tindlund R, Sæle P, Blomhoff R, Jacobsen G, Havstam C, Rizell S, Enocson L, Hagberg C, Najar Chalien M, Paganini A, Lundeborg I, Marcusson A, Mjönes AB, Gustavsson A, Hayden C, McAleer E, Slevan E, Gregg T, Worthington H
J Plast Surg Hand Surg 2017 Feb;51(1):2-13. doi: 10.1080/2000656X.2016.1263202. PMID: 28218559

Prognosis

Speech and Audiology Outcomes After Single-Stage Versus Early 2-Stage Cleft Palate Repair.
Crowley JS, Friesen TL, Gabriel RA, Hsieh S, Wacenske A, Deal D, Tsai C, Lance S, Gosman AA
Ann Plast Surg 2021 May 1;86(5S Suppl 3):S360-S366. doi: 10.1097/SAP.0000000000002747. PMID: 33559999
Oronasal Fistula Risk After Palate Repair.
Pollard SH, Skirko JR, Dance D, Reinemer H, Yamashiro D, Lyon NF, Collingridge DS
Cleft Palate Craniofac J 2021 Jan;58(1):35-41. Epub 2020 Jun 23 doi: 10.1177/1055665620931707. PMID: 32573252
Speech of Patients With Unilateral Complete Cleft Lip and Palate: Comparison of Three Different Surgical Protocols for Primary Repair.
Ahti V, Alaluusua S, Rautio J, Leikola J, Hukki J, Saarikko A
J Craniofac Surg 2020 May/Jun;31(3):e291-e296. doi: 10.1097/SCS.0000000000006242. PMID: 32068730
A Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 1. Planning and management.
Semb G, Enemark H, Friede H, Paulin G, Lilja J, Rautio J, Andersen M, Åbyholm F, Lohmander A, Shaw W, Mølsted K, Heliövaara A, Bolund S, Hukki J, Vindenes H, Davenport P, Arctander K, Larson O, Berggren A, Whitby D, Leonard A, Neovius E, Elander A, Willadsen E, Bannister RP, Bradbury E, Henningsson G, Persson C, Eyres P, Emborg B, Kisling-Møller M, Küseler A, Granhof Black B, Schöps A, Bau A, Boers M, Andersen HS, Jeppesen K, Marxen D, Paaso M, Hölttä E, Alaluusua S, Turunen L, Humerinta K, Elfving-Little U, Tørdal IB, Kjøll L, Aukner R, Hide Ø, Feragen KB, Rønning E, Skaare P, Brinck E, Semmingsen AM, Lindberg N, Bowden M, Davies J, Mooney J, Bellardie H, Schofield N, Nyberg J, Lundberg M, Karsten AL, Larson M, Holmefjord A, Reisæter S, Pedersen NH, Rasmussen T, Tindlund R, Sæle P, Blomhoff R, Jacobsen G, Havstam C, Rizell S, Enocson L, Hagberg C, Najar Chalien M, Paganini A, Lundeborg I, Marcusson A, Mjönes AB, Gustavsson A, Hayden C, McAleer E, Slevan E, Gregg T, Worthington H
J Plast Surg Hand Surg 2017 Feb;51(1):2-13. doi: 10.1080/2000656X.2016.1263202. PMID: 28218559
Transverse changes after surgical closure of complete cleft lip, alveolus and palate.
Lisson JA, Schilke R, Tränkmann J
Clin Oral Investig 1999 Mar;3(1):18-24. doi: 10.1007/s007840050073. PMID: 10522188

Clinical prediction guides

Long-term Follow-up of Bilateral Cleft Lip and Palate: Incidence of Speech-Correcting Surgeries and Fistula Formation.
Gustafsson C, Heliövaara A, Rautio J, Leikola J
Cleft Palate Craniofac J 2023 Oct;60(10):1241-1249. Epub 2022 Jun 20 doi: 10.1177/10556656221102816. PMID: 35726173Free PMC Article
Oronasal Fistula Risk After Palate Repair.
Pollard SH, Skirko JR, Dance D, Reinemer H, Yamashiro D, Lyon NF, Collingridge DS
Cleft Palate Craniofac J 2021 Jan;58(1):35-41. Epub 2020 Jun 23 doi: 10.1177/1055665620931707. PMID: 32573252
Unilateral Cleft Lip and Palate Surgical Protocols and Facial Growth Outcomes.
Pereira RMR, Siqueira N, Costa E, Vale DD, Alonso N
J Craniofac Surg 2018 Sep;29(6):1562-1568. doi: 10.1097/SCS.0000000000004810. PMID: 30373095
A Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 1. Planning and management.
Semb G, Enemark H, Friede H, Paulin G, Lilja J, Rautio J, Andersen M, Åbyholm F, Lohmander A, Shaw W, Mølsted K, Heliövaara A, Bolund S, Hukki J, Vindenes H, Davenport P, Arctander K, Larson O, Berggren A, Whitby D, Leonard A, Neovius E, Elander A, Willadsen E, Bannister RP, Bradbury E, Henningsson G, Persson C, Eyres P, Emborg B, Kisling-Møller M, Küseler A, Granhof Black B, Schöps A, Bau A, Boers M, Andersen HS, Jeppesen K, Marxen D, Paaso M, Hölttä E, Alaluusua S, Turunen L, Humerinta K, Elfving-Little U, Tørdal IB, Kjøll L, Aukner R, Hide Ø, Feragen KB, Rønning E, Skaare P, Brinck E, Semmingsen AM, Lindberg N, Bowden M, Davies J, Mooney J, Bellardie H, Schofield N, Nyberg J, Lundberg M, Karsten AL, Larson M, Holmefjord A, Reisæter S, Pedersen NH, Rasmussen T, Tindlund R, Sæle P, Blomhoff R, Jacobsen G, Havstam C, Rizell S, Enocson L, Hagberg C, Najar Chalien M, Paganini A, Lundeborg I, Marcusson A, Mjönes AB, Gustavsson A, Hayden C, McAleer E, Slevan E, Gregg T, Worthington H
J Plast Surg Hand Surg 2017 Feb;51(1):2-13. doi: 10.1080/2000656X.2016.1263202. PMID: 28218559
Primary repair of broad bilateral complete cleft palate with hard palate rotation flap.
Lv C, Cai C, Tao R, Song JX, Zhang JD
J Craniofac Surg 2013 May;24(3):809-11. doi: 10.1097/SCS.0b013e31828dcd1d. PMID: 23714885

Recent systematic reviews

The need for maxillary osteotomy after primary cleft surgery: A systematic review framing a retrospective study.
Tache A, Mommaerts MY
J Craniomaxillofac Surg 2020 Oct;48(10):919-927. Epub 2020 Jul 19 doi: 10.1016/j.jcms.2020.07.005. PMID: 32768251
Early or delayed palatoplasty in complete unilateral cleft lip and palate patients? A systematic review of the effects on maxillary growth.
Salgado KR, Wendt AR, Fernandes Fagundes NC, Maia LC, Normando D, Leão PB
J Craniomaxillofac Surg 2019 Nov;47(11):1690-1698. Epub 2019 Jul 3 doi: 10.1016/j.jcms.2019.06.017. PMID: 31677987
Treatment outcomes of pre-surgical infant orthopedics in patients with non-syndromic cleft lip and/or palate: A systematic review and meta-analysis of randomized controlled trials.
Hosseini HR, Kaklamanos EG, Athanasiou AE
PLoS One 2017;12(7):e0181768. Epub 2017 Jul 24 doi: 10.1371/journal.pone.0181768. PMID: 28742129Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...