U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Neoplasm of the posterior pituitary

MedGen UID:
235368
•Concept ID:
C1334957
•
Neoplastic Process
Synonyms: neoplasm of neurohypophysis; Neoplasm of the neurohypophysis; Neurohypophysis Neoplasm; Neurohypophysis neoplasm; neurohypophysis neoplasm; neurohypophysis neoplasm (disease); Neurohypophysis Tumor; Neurohypophysis tumor; neurohypophysis tumor; neurohypophysis tumour; Neurohypophysis tumour; Pituicyte Tumor; Pituicyte Tumor Family; PITUICYTOMA, benign; Posterior Pituitary Gland Neoplasm; posterior pituitary gland neoplasm; Posterior Pituitary Gland Tumor; posterior pituitary gland tumor; posterior pituitary gland tumour; Posterior Pituitary Neoplasm; posterior pituitary neoplasm; Posterior Pituitary Tumor; posterior pituitary tumor; posterior pituitary tumour; tumor of neurohypophysis; tumour of neurohypophysis
 
HPO: HP:0011752
Monarch Initiative: MONDO:0003257

Definition

The presence of a neoplasm (tumor) in the neurohypophysis, which is also known as the posterior lobe of the hypophysis. [from HPO]

Professional guidelines

PubMed

The Diagnosis and Treatment of Craniopharyngioma.
Müller HL
Neuroendocrinology 2020;110(9-10):753-766. Epub 2019 Nov 4 doi: 10.1159/000504512. PMID: 31678973
Risk-adapted, long-term management in childhood-onset craniopharyngioma.
Müller HL
Pituitary 2017 Apr;20(2):267-281. doi: 10.1007/s11102-016-0751-0. PMID: 27604996
Risk-adapted treatment and follow-up management in childhood-onset craniopharyngioma.
Müller HL
Expert Rev Neurother 2016 May;16(5):535-48. Epub 2016 Mar 28 doi: 10.1586/14737175.2016.1166959. PMID: 26982163

Recent clinical studies

Etiology

Overview of the 2022 WHO Classification of Pituitary Tumors.
Asa SL, Mete O, Perry A, Osamura RY
Endocr Pathol 2022 Mar;33(1):6-26. Epub 2022 Mar 15 doi: 10.1007/s12022-022-09703-7. PMID: 35291028
Genetic and epigenetic characterization of posterior pituitary tumors.
Schmid S, Solomon DA, Perez E, Thieme A, Kleinschmidt-DeMasters BK, Giannini C, Reinhardt A, Asa SL, Mete O, Stichel D, Siewert C, Dittmayer C, Hasselblatt M, Paulus W, Nagel C, Harter PN, Schittenhelm J, Honegger J, Rushing E, Coras R, Pfister SM, Buslei R, Koch A, Perry A, Jones DTW, von Deimling A, Capper D, Lopes MB
Acta Neuropathol 2021 Dec;142(6):1025-1043. Epub 2021 Oct 18 doi: 10.1007/s00401-021-02377-1. PMID: 34661724Free PMC Article
Modern endoscopic skull base neurosurgery.
Martinez-Perez R, Requena LC, Carrau RL, Prevedello DM
J Neurooncol 2021 Feb;151(3):461-475. Epub 2021 Feb 21 doi: 10.1007/s11060-020-03610-9. PMID: 33611712
Overview of the 2017 WHO Classification of Pituitary Tumors.
Mete O, Lopes MB
Endocr Pathol 2017 Sep;28(3):228-243. doi: 10.1007/s12022-017-9498-z. PMID: 28766057
Hypopituitarism.
Higham CE, Johannsson G, Shalet SM
Lancet 2016 Nov 12;388(10058):2403-2415. Epub 2016 Mar 31 doi: 10.1016/S0140-6736(16)30053-8. PMID: 27041067

Diagnosis

Overview of the 2022 WHO Classification of Pituitary Tumors.
Asa SL, Mete O, Perry A, Osamura RY
Endocr Pathol 2022 Mar;33(1):6-26. Epub 2022 Mar 15 doi: 10.1007/s12022-022-09703-7. PMID: 35291028
The Diagnosis and Treatment of Craniopharyngioma.
Müller HL
Neuroendocrinology 2020;110(9-10):753-766. Epub 2019 Nov 4 doi: 10.1159/000504512. PMID: 31678973
Hypopituitarism.
Higham CE, Johannsson G, Shalet SM
Lancet 2016 Nov 12;388(10058):2403-2415. Epub 2016 Mar 31 doi: 10.1016/S0140-6736(16)30053-8. PMID: 27041067
Craniopharyngioma.
Müller HL
Endocr Rev 2014 Jun;35(3):513-43. Epub 2014 Jan 27 doi: 10.1210/er.2013-1115. PMID: 24467716
The oxytocin receptor system: structure, function, and regulation.
Gimpl G, Fahrenholz F
Physiol Rev 2001 Apr;81(2):629-83. doi: 10.1152/physrev.2001.81.2.629. PMID: 11274341

Therapy

Insights into non-classic and emerging causes of hypopituitarism.
Prodam F, Caputo M, Mele C, Marzullo P, Aimaretti G
Nat Rev Endocrinol 2021 Feb;17(2):114-129. Epub 2020 Nov 27 doi: 10.1038/s41574-020-00437-2. PMID: 33247226
Hypopituitarism.
Higham CE, Johannsson G, Shalet SM
Lancet 2016 Nov 12;388(10058):2403-2415. Epub 2016 Mar 31 doi: 10.1016/S0140-6736(16)30053-8. PMID: 27041067
Management of diabetes insipidus and adipsia in the child.
Di Iorgi N, Morana G, Napoli F, Allegri AE, Rossi A, Maghnie M
Best Pract Res Clin Endocrinol Metab 2015 Jun;29(3):415-36. Epub 2015 May 9 doi: 10.1016/j.beem.2015.04.013. PMID: 26051300
Xanthomatous hypophysitis.
Hanna B, Li YM, Beutler T, Goyal P, Hall WA
J Clin Neurosci 2015 Jul;22(7):1091-7. Epub 2015 May 6 doi: 10.1016/j.jocn.2015.01.019. PMID: 25957783
Craniopharyngioma.
Müller HL
Endocr Rev 2014 Jun;35(3):513-43. Epub 2014 Jan 27 doi: 10.1210/er.2013-1115. PMID: 24467716

Prognosis

Metastatic Spread to the Pituitary.
Shimon I
Neuroendocrinology 2020;110(9-10):805-808. Epub 2020 Feb 27 doi: 10.1159/000506810. PMID: 32101869
Tumors of the Neurohypophysis: One Unit's Experience and Literature Review.
Borg A, Jaunmuktane Z, Dorward N
World Neurosurg 2020 Feb;134:e968-e978. Epub 2019 Nov 14 doi: 10.1016/j.wneu.2019.11.043. PMID: 31734425
Hypopituitarism.
Higham CE, Johannsson G, Shalet SM
Lancet 2016 Nov 12;388(10058):2403-2415. Epub 2016 Mar 31 doi: 10.1016/S0140-6736(16)30053-8. PMID: 27041067
Craniopharyngioma.
Müller HL
Endocr Rev 2014 Jun;35(3):513-43. Epub 2014 Jan 27 doi: 10.1210/er.2013-1115. PMID: 24467716
Neurology of pregnancy.
Block HS, Biller J
Handb Clin Neurol 2014;121:1595-622. doi: 10.1016/B978-0-7020-4088-7.00105-X. PMID: 24365437

Clinical prediction guides

Genetic and epigenetic characterization of posterior pituitary tumors.
Schmid S, Solomon DA, Perez E, Thieme A, Kleinschmidt-DeMasters BK, Giannini C, Reinhardt A, Asa SL, Mete O, Stichel D, Siewert C, Dittmayer C, Hasselblatt M, Paulus W, Nagel C, Harter PN, Schittenhelm J, Honegger J, Rushing E, Coras R, Pfister SM, Buslei R, Koch A, Perry A, Jones DTW, von Deimling A, Capper D, Lopes MB
Acta Neuropathol 2021 Dec;142(6):1025-1043. Epub 2021 Oct 18 doi: 10.1007/s00401-021-02377-1. PMID: 34661724Free PMC Article
Imaging findings in hypophysitis: a review.
Caranci F, Leone G, Ponsiglione A, Muto M, Tortora F, Muto M, Cirillo S, Brunese L, Cerase A
Radiol Med 2020 Mar;125(3):319-328. Epub 2019 Dec 20 doi: 10.1007/s11547-019-01120-x. PMID: 31863360
Hypopituitarism.
Higham CE, Johannsson G, Shalet SM
Lancet 2016 Nov 12;388(10058):2403-2415. Epub 2016 Mar 31 doi: 10.1016/S0140-6736(16)30053-8. PMID: 27041067
Management of diabetes insipidus and adipsia in the child.
Di Iorgi N, Morana G, Napoli F, Allegri AE, Rossi A, Maghnie M
Best Pract Res Clin Endocrinol Metab 2015 Jun;29(3):415-36. Epub 2015 May 9 doi: 10.1016/j.beem.2015.04.013. PMID: 26051300
Pituicytoma.
Kowalski RJ, Prayson RA, Mayberg MR
Ann Diagn Pathol 2004 Oct;8(5):290-4. doi: 10.1016/j.anndiagpath.2004.07.006. PMID: 15494936

Recent systematic reviews

Fatigue following head and neck cancer radiotherapy: a systematic review of dose correlates.
Leong WC, Manan HA, Hsien CCM, Wong YF, Yahya N
Support Care Cancer 2024 Jun 26;32(7):460. doi: 10.1007/s00520-024-08655-4. PMID: 38918218
Primary Tumors of the Posterior Pituitary Gland: A Systematic Review of the Literature in Light of the New 2017 World Health Organization Classification of Pituitary Tumors.
Whipple SG, Savardekar AR, Rao S, Mahadevan A, Guthikonda B, Kosty JA
World Neurosurg 2021 Jan;145:148-158. Epub 2020 Sep 8 doi: 10.1016/j.wneu.2020.09.023. PMID: 32916355
Primary tumors of the posterior pituitary: A systematic review.
Guerrero-Pérez F, Marengo AP, Vidal N, Iglesias P, Villabona C
Rev Endocr Metab Disord 2019 Jun;20(2):219-238. doi: 10.1007/s11154-019-09484-1. PMID: 30864049
Granular Cell Tumor of the Neurohypophysis: 3 Cases and a Systematic Literature Review of 98 Cases.
Zhang Y, Teng Y, Zhu H, Lu L, Deng K, Pan H, Yao Y
World Neurosurg 2018 Oct;118:e621-e630. Epub 2018 Jul 11 doi: 10.1016/j.wneu.2018.07.004. PMID: 30017767
Infundibulo-tuberal or not strictly intraventricular craniopharyngioma: evidence for a major topographical category.
Pascual JM, Prieto R, Carrasco R
Acta Neurochir (Wien) 2011 Dec;153(12):2403-25; discussion 2426. Epub 2011 Sep 15 doi: 10.1007/s00701-011-1149-4. PMID: 21918833

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...