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Taf9 TBP-associated factor 9 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32762, updated on 2-Nov-2024

Summary

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Official Symbol
Taf9provided by FlyBase
Official Full Name
TBP-associated factor 9provided by FlyBase
Primary source
FLYBASE:FBgn0000617
Locus tag
Dmel_CG6474
See related
AllianceGenome:FB:FBgn0000617
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG6474; d40; dme-TAFII40; Dmel\CG6474; dmTaf9; dmTAF9; dTAF42; dTaf9; dTAF9; dTAFII42; dTAF[[40]]; dTAF[[II]]40; dTAF[[II]]42; e(y)1; E(y)1; e(y)4; e(y)[1]; p42; Taf40; TAF40; TAF40/42; TAF40/42/e(y)1; taf40/e(y)1; Taf42; TAF42; taf9; TAF9; TafII40; TAFII40; TAFII40(42); TAF[II]40; TAF[[II]]; Taf[[II]]40; TAF[[II]]40; TAF[[II]]40/42; TAF[[II]]42; TFIID; TFIID 42; TFIID-p42
Summary
Enables protein heterodimerization activity and transcription coactivator binding activity. Contributes to RNA polymerase II general transcription initiation factor activity. Involved in follicle cell of egg chamber development and transcription by RNA polymerase II. Located in nucleus. Part of SAGA complex and transcription factor TFIID complex. Is expressed in male accessory gland; organism; seminal vesicle; spermatocyte; and testis. Orthologous to several human genes including TAF9 (TATA-box binding protein associated factor 9). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

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See Taf9 in Genome Data Viewer
Location:
16E1-16E1; 1-59 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (17842161..17843348)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (17736194..17737381)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Suppressor of Cytokine Signaling at 16D Neighboring gene long non-coding RNA:CR44691 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Uncoupling protein 4A Neighboring gene uncharacterized protein Neighboring gene Spt7 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Protease footprinting reveals a surface on transcription factor TFIIB that serves as an interface for activators and coactivators. Hori R, et al. Proc Natl Acad Sci U S A, 1995 Jun 20. PMID 7597078, Free PMC Article
  2. DA-complex assembly activity required for VP16C transcriptional activation. Kobayashi N, et al. Mol Cell Biol, 1998 Jul. PMID 9632787, Free PMC Article
  3. [A new method of cloning Drosophila melanogaster genes marked with a highly copies mobile genetic element]. Soldatov AV, et al. Genetika, 1996 Dec. PMID 9102367
  4. The role of cryptic ancestral symmetry in histone folding mechanisms across Eukarya and Archaea. Zhao H, et al. PLoS Comput Biol, 2024 Jan. PMID 38181064, Free PMC Article
  5. [Nuclear protein e(y)2 from Drosophila melanogaster participates in transcription control]. Georgieva SG, et al. Genetika, 2001 Jan. PMID 11234421

See all (153) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. TRF2 and TAF9 have roles in regulating lipid droplet size and phospholipid fatty acid composition
    Title: Drosophila TRF2 and TAF9 regulate lipid droplet size and phospholipid fatty acid composition.
  2. association of the NICD-Su(H)-Mastermind complex with E(y)1/TAF9 in response to Notch activation recruits the transcription initiation complex to induce Notch target genes, coupling Notch signaling with the transcription machinery
    Title: E(y)1/TAF9 mediates the transcriptional output of Notch signaling in Drosophila.
  3. GAGA factor and the TFIID complex collaborate in generating an open chromatin structure at the Drosophila melanogaster hsp26 promoter.
    Title: GAGA factor and the TFIID complex collaborate in generating an open chromatin structure at the Drosophila melanogaster hsp26 promoter.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
contributes_to RNA polymerase II general transcription initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to RNA polymerase II general transcription initiation factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription coactivator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transcription coactivator binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA-templated transcription initiation IEA
Inferred from Electronic Annotation
more info
  
involved_in RNA polymerase II preinitiation complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in follicle cell of egg chamber development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in transcription initiation at RNA polymerase II promoter ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
part_of SAGA complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of SAGA complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of SAGA complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
part_of transcription factor TFIID complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of transcription factor TFIID complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of transcription factor TFIID complex IPI
Inferred from Physical Interaction
more info
 PubMed 
part_of transcription factor TFIID complex ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
TBP-associated factor 9
Names
CG6474-PA
TBP-associated factor
TBP-associated factor 40kD
Taf9-PA
enhancer of yellow 1
enhancer of yellow 4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    17842161..17843348
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078667.4 → NP_523391.3  TBP-associated factor 9 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523391.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q27272, Q95RJ4, Q9VX16
    UniProtKB/TrEMBL
    A8WHK8
    Related
    FBpp0074237
    Conserved Domains (1) summary
    pfam02291
    Location:16 → 135
    TFIID-31kDa; Transcription initiation factor IID, 31kD subunit
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q27272.1 Q27272

Gene LinkOut

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