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GIT2 GIT ArfGAP 2 [ Gallus gallus (chicken) ]

Gene ID: 374035, updated on 17-Aug-2024

Summary

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Symbol
GIT2provided by CGNC
Full Name
GIT ArfGAP 2provided by CGNC
Primary source
CGNC:3839
See related
Ensembl:ENSGALG00010021783
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Annotation information
Annotation category: suggests misassembly
Orthologs
human mouse all
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Genomic context

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See GIT2 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
20
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 15 NC_052546.1 (6873316..6895991, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 15 NC_052587.1 (6883811..6906511, complement)

Chromosome 15 - NC_052546.1Genomic Context describing neighboring genes Neighboring gene glycolipid transfer protein Neighboring gene trichoplein keratin filament binding Neighboring gene ankyrin repeat domain 13A Neighboring gene uncharacterized LOC107051594

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Analysis of the subcellular distribution of avian p95-APP2, an ARF-GAP orthologous to mammalian paxillin kinase linker. Paris S, et al. Int J Biochem Cell Biol, 2002 Jul. PMID 11950598
  2. Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling. Turner CE, et al. J Cell Biol, 1999 May 17. PMID 10330411, Free PMC Article
  3. A comprehensive collection of chicken cDNAs. Boardman PE, et al. Curr Biol, 2002 Nov 19. PMID 12445392
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in brain development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of ARF protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ARF GTPase-activating protein GIT2
Names
G protein-coupled receptor kinase interactor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001395909.1 → NP_001382838.1  ARF GTPase-activating protein GIT2

    Status: VALIDATED

    Source sequence(s)
    AF134571, BU405099, CN383239, CO419884
    UniProtKB/TrEMBL
    Q9DE64, Q9Y621
    Related
    ENSGALP00010031896.1, ENSGALT00010052990.1
    Conserved Domains (6) summary
    sd00045
    Location:137 → 165
    ANK; ANK repeat [structural motif]
    cd08847
    Location:1 → 111
    ArfGap_GIT2; GIT2 GTPase activating protein for Arf
    pfam08518
    Location:266 → 294
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:634 → 750
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:137 → 229
    Ank_2; Ankyrin repeats (3 copies)
    pfam16559
    Location:414 → 478
    GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052546.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    6873316..6895991 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052587.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    6883811..6906511 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_204206.1: Suppressed sequence

    Description
    NM_204206.1: This RefSeq was removed because currently there is insufficient support for the transcript.
Nucleotide Protein
Heading Accession and Version

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