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Cog1 Component of oligomeric golgi complex 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41479, updated on 2-Nov-2024

Summary

Official Symbol
Cog1provided by FlyBase
Official Full Name
Component of oligomeric golgi complex 1provided by FlyBase
Primary source
FLYBASE:FBgn0037998
Locus tag
Dmel_CG4848
See related
AllianceGenome:FB:FBgn0037998
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG4848; cog1; COG1; Dmel\CG4848
Summary
Predicted to be involved in Golgi organization and intra-Golgi vesicle-mediated transport. Part of Golgi transport complex. Is expressed in several structures, including adult head; gland; gut section; salivary gland body primordium; and spermatozoon. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIg. Orthologous to human COG1 (component of oligomeric golgi complex 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See Cog1 in Genome Data Viewer
Location:
87B2-87B2; 3-52 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12213792..12219686, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8039514..8045408, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene transfer RNA:Threonine-TGT 1-1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR46012 Neighboring gene uncharacterized protein Neighboring gene Radial spoke binding protein 15 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in Golgi organization ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in intra-Golgi vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
involved_in intra-Golgi vesicle-mediated transport ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi apparatus ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of Golgi transport complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of Golgi transport complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
component of oligomeric golgi complex 1
Names
CG4848-PA
CG4848-PB
CG4848-PC
Cog1-PA
Cog1-PB
Cog1-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    12213792..12219686 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275568.1NP_001262497.1  component of oligomeric golgi complex 1, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262497.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VGC3
    UniProtKB/TrEMBL
    A0A0B4KGW7
    Conserved Domains (1) summary
    pfam08700
    Location:484
    Vps51; Vps51/Vps67
  2. NM_141905.3NP_650162.1  component of oligomeric golgi complex 1, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650162.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VGC3
    UniProtKB/TrEMBL
    A0A0B4KGW7
    Related
    FBpp0082093
    Conserved Domains (1) summary
    pfam08700
    Location:484
    Vps51; Vps51/Vps67
  3. NM_001275567.1NP_001262496.1  component of oligomeric golgi complex 1, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262496.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4KH76
    Conserved Domains (1) summary
    pfam08700
    Location:484
    Vps51; Vps51/Vps67