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FAT1 FAT atypical cadherin 1 [ Bos taurus (domestic cattle) ]

Gene ID: 508251, updated on 10-Oct-2024

Summary

Official Symbol
FAT1provided by VGNC
Official Full Name
FAT atypical cadherin 1provided by VGNC
Primary source
VGNC:VGNC:52771
See related
BGD:BT13826; Ensembl:ENSBTAG00000020657
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
FAT
Annotation information
Annotation category: suggests misassembly
Orthologs
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Genomic context

See FAT1 in Genome Data Viewer
Location:
chromosome: 27
Exon count:
32
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 27 NC_037354.1 (16420184..16546113, complement)

Chromosome 27 - NC_037354.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132344050 Neighboring gene melatonin receptor 1A Neighboring gene small ribosomal subunit protein eS28-like Neighboring gene uncharacterized LOC101905556

Genomic regions, transcripts, and products

Genomic Sequence:
NC_037354.1 Chromosome 27 Reference ARS-UCD2.0 Primary Assembly

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
protocadherin Fat 1
Names
FAT tumor suppressor homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001192992.2NP_001179921.2  protocadherin Fat 1 precursor

    Status: VALIDATED

    Source sequence(s)
    CO875056, DAAA02060206, DAAA02060207, DAAA02060208, DY177990
    UniProtKB/TrEMBL
    E1BKL9
    Related
    ENSBTAP00000027527.6, ENSBTAT00000027527.6
    Conserved Domains (5) summary
    cd11304
    Location:32343331
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00282
    Location:38543985
    LamG; Laminin G domain
    cd00054
    Location:41274163
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00008
    Location:40934123
    EGF; EGF-like domain
    cl09101
    Location:277356
    E_set; Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037354.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    16420184..16546113 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010820249.4XP_010818551.2  protocadherin Fat 1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1M5W5, E1BKL9
    Related
    ENSBTAP00000063675.1, ENSBTAT00000082602.2
    Conserved Domains (5) summary
    cd11304
    Location:32343331
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00282
    Location:38543985
    LamG; Laminin G domain
    cd00054
    Location:41274163
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam00008
    Location:40934123
    EGF; EGF-like domain
    cl09101
    Location:277356
    E_set; Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus
  2. XM_059882182.1XP_059738165.1  protocadherin Fat 1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1M5W5
  3. XM_059882180.1XP_059738163.1  protocadherin Fat 1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1M5W5
  4. XM_059882181.1XP_059738164.1  protocadherin Fat 1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1M5W5
  5. XM_059882183.1XP_059738166.1  protocadherin Fat 1 isoform X2

RNA

  1. XR_815911.4 RNA Sequence