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SLC6A5 solute carrier family 6 member 5 [ Bos taurus (domestic cattle) ]

Gene ID: 528050, updated on 4-Oct-2024

Summary

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Official Symbol
SLC6A5provided by VGNC
Official Full Name
solute carrier family 6 member 5provided by VGNC
Primary source
VGNC:VGNC:56281
See related
BGD:BT13315; Ensembl:ENSBTAG00000014300
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See SLC6A5 in Genome Data Viewer
Location:
chromosome: 29
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 29 NC_037356.1 (24316604..24373268, complement)

Chromosome 29 - NC_037356.1Genomic Context describing neighboring genes Neighboring gene neural EGFL like 1 Neighboring gene uncharacterized LOC132344181 Neighboring gene uncharacterized protein C11orf98-like Neighboring gene protein arginine methyltransferase 3 Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene HIV-1 Tat interactive protein 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037356.1 Chromosome 29 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of congenital muscular dystonia 2 associated with an inherited GlyT2 defect in Belgian Blue cattle from the United Kingdom. Gill JL, et al. Anim Genet, 2012 Jun. PMID 22486497
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables glycine:sodium symporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glycine import across plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sodium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synaptic transmission, glycinergic IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sodium- and chloride-dependent glycine transporter 2
Names
solute carrier family 6 (neurotransmitter transporter), member 5
solute carrier family 6 (neurotransmitter transporter, glycine), member 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037356.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    24316604..24373268 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015461176.3 → XP_015316662.2  sodium- and chloride-dependent glycine transporter 2

    UniProtKB/TrEMBL
    A0A3Q1MHT9
    Related
    ENSBTAP00000019000.3, ENSBTAT00000019000.4
    Conserved Domains (1) summary
    cd11499
    Location:207 → 803
    SLC6sbd_GlyT2; Na(+)- and Cl(-)-dependent glycine transporter GlyT2; solute-binding domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials