Sanger Imputation Service

This is a free genotype imputation and phasing service provided by the Wellcome Sanger Institute. You can upload GWAS data in VCF or 23andMe format and receive imputed and phased genomes back. Click here to learn more and follow us on Twitter.

Before you start

Be sure to read through the instructions.

You will need to set up a free account with Globus and have Globus Connect running at your institute or on your computer to transfer files to and from the service.

Ready to start?

If you are ready to upload your data, please fill in the details below to register an imputation and/or phasing job. If you need more information, see the about page. See also our Privacy and Security statement.

What is this

News @sangerimpute

30/1/2017
Support for chromosome X has been added to all pipelines. PBWT has been updated to increase imputation accuracy of dosages and fix some bugs. See ChangeLog.

31/10/2016
New African Genome Resources panel with 9,912 haplotypes (6,230 African) is now available.

11/04/2016
Thanks to EAGLE2, we can now return phased data. The HRC panel has been updated to r1.1 to fix a known issue. See ChangeLog for more details.

15/02/2016
Globus API changed, please see updated instructions.

17/12/2015
New status page and reworked internals. See ChangeLog.

09/11/2015
Pipeline updated to add some features requested by users. See ChangeLog.

10/07/2015
The HRC.r1 panel is now available to all (however, please read this release note).

24/04/2015
The HRC.r1 panel is now available to HRC consortium members.

21/04/2015
Added page to find out the status of your imputation job.

08/04/2015
Soft launch. Please help us improve the documentation on the site by sending us feedback.

17/02/2015
We are about to launch!