FMNL2
Formin-like protein 2
Protein Summary
Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics. This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
- ENST00000288670
- ENSP00000288670
- ENSG00000157827
- FHOD2
- KIAA1902
- FHOD2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
protein domain | 0.97 | ||
transcription factor perturbation | 0.91 | ||
ligand (protein) perturbation | 0.83 | ||
virus perturbation | 0.79 | ||
microRNA | 0.77 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 41.23 (req: < 5)
Gene RIFs: 32 (req: <= 3)
Antibodies: 94 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 41.23 (req: >= 5)
Gene RIFs: 32 (req: > 3)
Antibodies: 94 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0