Abstract
In a prospective study evaluating risk factors for indinavir-related renal colic in 555 HIV-infected patients receiving highly active antiretroviral therapy, followed-up fir 24 months, 23.6% developed one or more renal colic episodes, and 50 patients stopped indinavir. No correlation was observed between renal colic onset and sex, age, CD4 cell count, history, and hepatitis B or C virus co-infection, but baseline anthropometric values were significantly related to the onset of renal colic.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Body Mass Index
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Colic / chemically induced*
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Dose-Response Relationship, Drug
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Female
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HIV Infections / drug therapy*
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HIV Protease Inhibitors / administration & dosage
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HIV Protease Inhibitors / adverse effects*
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Humans
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Indinavir / administration & dosage
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Indinavir / adverse effects*
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Kidney Calculi
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Kidney Diseases / chemically induced*
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Male
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Predictive Value of Tests
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Prospective Studies
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Risk Factors
Substances
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HIV Protease Inhibitors
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Indinavir