Health promotion policies--including laws that regulate safe products, environments, and behaviors--are among the most effective mechanisms for reducing childhood injuries for large segments of the population. In this article, five examples of safety legislation and regulation to reduce childhood injury are described. Two such efforts are aimed at preventing injury-producing events from occurring: child-resistant packaging for medications and hazardous substances, and graduated licensing for teen drivers. Three other examples illustrate the value and complexities of policies designed to prevent an injury once a hazardous event has occurred: bicycle helmet legislation, children's sleepwear standards, and child safety seat laws. One important role of health promotion is to tackle not only how health promotion policies and politics can improve child health, but also how to educate legislators and policy makers in the process.