Chromosome 17q21 SNP rs8076131 risk allele associates with airway smooth muscle hypertrophy in fatal asthma

Clin Exp Allergy. 2020 Nov;50(11):1270-1273. doi: 10.1111/cea.13708. Epub 2020 Aug 5.

Authors

Marina Miller¹, Peter Rosenthal¹, Ning Weng¹, Alex Pham¹, Gyu-Young Hur¹, John Elliot², Francis H Y Green³, Alan James², David H Broide¹

Affiliations

¹ Department of Medicine, University of California San Diego, La Jolla, CA, USA.
² Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia.
³ Department of Pathology & Laboratory Medicine, University of Calgary, Alberta, Canada.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural

MeSH terms

Adult
Airway Remodeling*
Asthma / genetics*
Asthma / mortality
Asthma / pathology
Case-Control Studies
Chromosomes, Human, Pair 17*
Female
Genetic Predisposition to Disease
Humans
Hypertrophy
Lung / pathology*
Male
Middle Aged
Muscle, Smooth / pathology*
Phenotype
Polymorphism, Single Nucleotide*
Risk Assessment
Risk Factors

Grants and funding