First use of the anti-VWF nanobody caplacizumab to treat iTTP in pregnancy

Br J Haematol. 2022 Feb;196(3):e30-e33. doi: 10.1111/bjh.17833. Epub 2021 Sep 29.

Lucas Kühne^{1

2}, Linus A Völker^{1

2}, Henning Hagmann^{1

2}, Holger Hägele^{1

2}, Thomas Osterholt^{1

2}, Dennis A Eichenauer³, Andreas Thomas⁴, Johanna Breuer⁴, Berthold Grüttner⁵, Ingo Gottschalk⁵, Martin Kann^{1

2}, Thomas Benzing^{1

2}, Mario Thevis⁴, Annette M Müller⁶, Paul T Brinkkoetter^{1

2}

¹ Department II of Internal Medicine and Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.
² Cologne Cluster of Excellence on Cellular Stress Responses in Ageing-Associated Diseases (CECAD), Cologne, Germany.
³ Department I of Internal Medicine, Center for Integrated Oncology, Aachen Bonn Cologne Dusseldorf, University of Cologne, Cologne, Germany.
⁴ Center for Preventive Doping Research, Institute of Biochemistry, German Sport University Cologne, Cologne, Germany.
⁵ Department of Obstetrics and Gynecology, University Hospital of Cologne, Cologne, Germany.
⁶ Department of Pathology/Pediatric Pathology, University Hospital of Cologne, University of Cologne, Cologne, Germany.

No abstract available

Keywords: platelets; pregnancy; thrombocytopenia; thrombotic haemolytic anaemia.

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