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494 results

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Page 1
Angiomodulin is a specific marker of vasculature and regulates vascular endothelial growth factor-A-dependent neoangiogenesis.
Hooper AT, Shmelkov SV, Gupta S, Milde T, Bambino K, Gillen K, Goetz M, Chavala S, Baljevic M, Murphy AJ, Valenzuela DM, Gale NW, Thurston G, Yancopoulos GD, Vahdat L, Evans T, Rafii S. Hooper AT, et al. Among authors: yancopoulos gd. Circ Res. 2009 Jul 17;105(2):201-8. doi: 10.1161/CIRCRESAHA.109.196790. Epub 2009 Jun 18. Circ Res. 2009. PMID: 19542015 Free PMC article.
Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development.
Gale NW, Dominguez MG, Noguera I, Pan L, Hughes V, Valenzuela DM, Murphy AJ, Adams NC, Lin HC, Holash J, Thurston G, Yancopoulos GD. Gale NW, et al. Among authors: yancopoulos gd. Proc Natl Acad Sci U S A. 2004 Nov 9;101(45):15949-54. doi: 10.1073/pnas.0407290101. Epub 2004 Nov 1. Proc Natl Acad Sci U S A. 2004. PMID: 15520367 Free PMC article.
Vascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesis.
Dominguez MG, Hughes VC, Pan L, Simmons M, Daly C, Anderson K, Noguera-Troise I, Murphy AJ, Valenzuela DM, Davis S, Thurston G, Yancopoulos GD, Gale NW. Dominguez MG, et al. Among authors: yancopoulos gd. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3243-8. doi: 10.1073/pnas.0611510104. Epub 2007 Feb 21. Proc Natl Acad Sci U S A. 2007. PMID: 17360632 Free PMC article.
Generation of functional multipotent adult stem cells from GPR125+ germline progenitors.
Seandel M, James D, Shmelkov SV, Falciatori I, Kim J, Chavala S, Scherr DS, Zhang F, Torres R, Gale NW, Yancopoulos GD, Murphy A, Valenzuela DM, Hobbs RM, Pandolfi PP, Rafii S. Seandel M, et al. Among authors: yancopoulos gd. Nature. 2007 Sep 20;449(7160):346-50. doi: 10.1038/nature06129. Nature. 2007. PMID: 17882221 Free PMC article.
CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors.
Shmelkov SV, Butler JM, Hooper AT, Hormigo A, Kushner J, Milde T, St Clair R, Baljevic M, White I, Jin DK, Chadburn A, Murphy AJ, Valenzuela DM, Gale NW, Thurston G, Yancopoulos GD, D'Angelica M, Kemeny N, Lyden D, Rafii S. Shmelkov SV, et al. Among authors: yancopoulos gd. J Clin Invest. 2008 Jun;118(6):2111-20. doi: 10.1172/JCI34401. J Clin Invest. 2008. PMID: 18497886 Free PMC article.
Embryonic stem cell tumor model reveals role of vascular endothelial receptor tyrosine phosphatase in regulating Tie2 pathway in tumor angiogenesis.
Li Z, Huang H, Boland P, Dominguez MG, Burfeind P, Lai KM, Lin HC, Gale NW, Daly C, Auerbach W, Valenzuela D, Yancopoulos GD, Thurston G. Li Z, et al. Among authors: yancopoulos gd. Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22399-404. doi: 10.1073/pnas.0911189106. Epub 2009 Dec 15. Proc Natl Acad Sci U S A. 2009. PMID: 20018779 Free PMC article.
Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in mice.
Shmelkov SV, Hormigo A, Jing D, Proenca CC, Bath KG, Milde T, Shmelkov E, Kushner JS, Baljevic M, Dincheva I, Murphy AJ, Valenzuela DM, Gale NW, Yancopoulos GD, Ninan I, Lee FS, Rafii S. Shmelkov SV, et al. Among authors: yancopoulos gd. Nat Med. 2010 May;16(5):598-602, 1p following 602. doi: 10.1038/nm.2125. Epub 2010 Apr 25. Nat Med. 2010. PMID: 20418887 Free PMC article.
Angiogenic sprouting into neural tissue requires Gpr124, an orphan G protein-coupled receptor.
Anderson KD, Pan L, Yang XM, Hughes VC, Walls JR, Dominguez MG, Simmons MV, Burfeind P, Xue Y, Wei Y, Macdonald LE, Thurston G, Daly C, Lin HC, Economides AN, Valenzuela DM, Murphy AJ, Yancopoulos GD, Gale NW. Anderson KD, et al. Among authors: yancopoulos gd. Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2807-12. doi: 10.1073/pnas.1019761108. Epub 2011 Jan 31. Proc Natl Acad Sci U S A. 2011. PMID: 21282641 Free PMC article.
494 results