Pratt S - Search Results

1

LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer.

Vakana E, Pratt S, Blosser W, Dowless M, Simpson N, Yuan XJ, Jaken S, Manro J, Stephens J, Zhang Y, Huber L, Peng SB, Stancato LF. Vakana E, et al. Among authors: pratt s. Oncotarget. 2017 Feb 7;8(6):9251-9266. doi: 10.18632/oncotarget.14002. Oncotarget. 2017. PMID: 27999210 Free PMC article.

2

Characterization of LY2228820 dimesylate, a potent and selective inhibitor of p38 MAPK with antitumor activity.

Campbell RM, Anderson BD, Brooks NA, Brooks HB, Chan EM, De Dios A, Gilmour R, Graff JR, Jambrina E, Mader M, McCann D, Na S, Parsons SH, Pratt SE, Shih C, Stancato LF, Starling JJ, Tate C, Velasco JA, Wang Y, Ye XS. Campbell RM, et al. Among authors: pratt se. Mol Cancer Ther. 2014 Feb;13(2):364-74. doi: 10.1158/1535-7163.MCT-13-0513. Epub 2013 Dec 19. Mol Cancer Ther. 2014. PMID: 24356814

3

Evaluation of the binding of the tricyclic isoxazole photoaffinity label LY475776 to multidrug resistance associated protein 1 (MRP1) orthologs and several ATP- binding cassette (ABC) drug transporters.

Dantzig AH, Shepard RL, Pratt SE, Tabas LB, Lander PA, Ma L, Paul DC, Williams DC, Peng SB, Slapak CA, Godinot N, Perry WL 3rd. Dantzig AH, et al. Biochem Pharmacol. 2004 Mar 15;67(6):1111-21. doi: 10.1016/j.bcp.2003.11.006. Biochem Pharmacol. 2004. PMID: 15006547

4

Efficacy of low-dose oral metronomic dosing of the prodrug of gemcitabine, LY2334737, in human tumor xenografts.

Pratt SE, Durland-Busbice S, Shepard RL, Donoho GP, Starling JJ, Wickremsinhe ER, Perkins EJ, Dantzig AH. Pratt SE, et al. Mol Cancer Ther. 2013 Apr;12(4):481-90. doi: 10.1158/1535-7163.MCT-12-0654. Epub 2013 Jan 31. Mol Cancer Ther. 2013. PMID: 23371859

5

Human carboxylesterase-2 hydrolyzes the prodrug of gemcitabine (LY2334737) and confers prodrug sensitivity to cancer cells.

Pratt SE, Durland-Busbice S, Shepard RL, Heinz-Taheny K, Iversen PW, Dantzig AH. Pratt SE, et al. Clin Cancer Res. 2013 Mar 1;19(5):1159-68. doi: 10.1158/1078-0432.CCR-12-1184. Epub 2013 Jan 16. Clin Cancer Res. 2013. PMID: 23325581

6

The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites.

Pratt S, Shepard RL, Kandasamy RA, Johnston PA, Perry W 3rd, Dantzig AH. Pratt S, et al. Mol Cancer Ther. 2005 May;4(5):855-63. doi: 10.1158/1535-7163.MCT-04-0291. Mol Cancer Ther. 2005. PMID: 15897250

7

Identification and characterization of the canine multidrug resistance-associated protein.

Ma L, Pratt SE, Cao J, Dantzig AH, Moore RE, Slapak CA. Ma L, et al. Mol Cancer Ther. 2002 Dec;1(14):1335-42. Mol Cancer Ther. 2002. PMID: 12516967

8

Selectivity of the multidrug resistance modulator, LY335979, for P-glycoprotein and effect on cytochrome P-450 activities.

Dantzig AH, Shepard RL, Law KL, Tabas L, Pratt S, Gillespie JS, Binkley SN, Kuhfeld MT, Starling JJ, Wrighton SA. Dantzig AH, et al. Among authors: pratt s. J Pharmacol Exp Ther. 1999 Aug;290(2):854-62. J Pharmacol Exp Ther. 1999. PMID: 10411602

9

Kinetic validation of the use of carboxydichlorofluorescein as a drug surrogate for MRP5-mediated transport.

Pratt S, Chen V, Perry WI 3rd, Starling JJ, Dantzig AH. Pratt S, et al. Eur J Pharm Sci. 2006 Apr;27(5):524-32. doi: 10.1016/j.ejps.2005.09.012. Epub 2005 Dec 5. Eur J Pharm Sci. 2006. PMID: 16337112

10

Characterization and application of a vinblastine-selected CACO-2 cell line for evaluation of p-glycoprotein.

Laska DA, Houchins JO, Pratt SE, Horn J, Xia X, Hanssen BR, Williams DC, Dantzig AH, Lindstrom T. Laska DA, et al. In Vitro Cell Dev Biol Anim. 2002 Jul-Aug;38(7):401-10. doi: 10.1290/1071-2690(2002)038<0401:CAAOAV>2.0.CO;2. In Vitro Cell Dev Biol Anim. 2002. PMID: 12534340

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