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Page 1
Accumulation of succinate controls activation of adipose tissue thermogenesis.
Mills EL, Pierce KA, Jedrychowski MP, Garrity R, Winther S, Vidoni S, Yoneshiro T, Spinelli JB, Lu GZ, Kazak L, Banks AS, Haigis MC, Kajimura S, Murphy MP, Gygi SP, Clish CB, Chouchani ET. Mills EL, et al. Nature. 2018 Aug;560(7716):102-106. doi: 10.1038/s41586-018-0353-2. Epub 2018 Jul 18. Nature. 2018. PMID: 30022159 Free PMC article.
Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation.
Peruzzotti-Jametti L, Bernstock JD, Vicario N, Costa ASH, Kwok CK, Leonardi T, Booty LM, Bicci I, Balzarotti B, Volpe G, Mallucci G, Manferrari G, Donegà M, Iraci N, Braga A, Hallenbeck JM, Murphy MP, Edenhofer F, Frezza C, Pluchino S. Peruzzotti-Jametti L, et al. Cell Stem Cell. 2018 Mar 1;22(3):355-368.e13. doi: 10.1016/j.stem.2018.01.020. Epub 2018 Feb 22. Cell Stem Cell. 2018. PMID: 29478844 Free PMC article.
Mechanism of succinate efflux upon reperfusion of the ischaemic heart.
Prag HA, Gruszczyk AV, Huang MM, Beach TE, Young T, Tronci L, Nikitopoulou E, Mulvey JF, Ascione R, Hadjihambi A, Shattock MJ, Pellerin L, Saeb-Parsy K, Frezza C, James AM, Krieg T, Murphy MP, Aksentijević D. Prag HA, et al. Cardiovasc Res. 2021 Mar 21;117(4):1188-1201. doi: 10.1093/cvr/cvaa148. Cardiovasc Res. 2021. PMID: 32766828 Free PMC article.
How should we talk about metabolism?
Murphy MP, O'Neill LAJ. Murphy MP, et al. Nat Immunol. 2020 Jul;21(7):713-715. doi: 10.1038/s41590-020-0691-8. Nat Immunol. 2020. PMID: 32409776 No abstract available.
The Causes and Consequences of Nonenzymatic Protein Acylation.
James AM, Smith CL, Smith AC, Robinson AJ, Hoogewijs K, Murphy MP. James AM, et al. Trends Biochem Sci. 2018 Nov;43(11):921-932. doi: 10.1016/j.tibs.2018.07.002. Epub 2018 Aug 18. Trends Biochem Sci. 2018. PMID: 30131192 Review.
Oncogenic KRAS Induces NIX-Mediated Mitophagy to Promote Pancreatic Cancer.
Humpton TJ, Alagesan B, DeNicola GM, Lu D, Yordanov GN, Leonhardt CS, Yao MA, Alagesan P, Zaatari MN, Park Y, Skepper JN, Macleod KF, Perez-Mancera PA, Murphy MP, Evan GI, Vousden KH, Tuveson DA. Humpton TJ, et al. Cancer Discov. 2019 Sep;9(9):1268-1287. doi: 10.1158/2159-8290.CD-18-1409. Epub 2019 Jul 1. Cancer Discov. 2019. PMID: 31263025 Free PMC article.
41 results