Bladder cancer risk and genetic variation in AKR1C3 and other metabolizing genes.
Figueroa JD, Malats N, García-Closas M, Real FX, Silverman D, Kogevinas M, Chanock S, Welch R, Dosemeci M, Lan Q, Tardón A, Serra C, Carrato A, García-Closas R, Castaño-Vinyals G, Rothman N.
Figueroa JD, et al.
Carcinogenesis. 2008 Oct;29(10):1955-62. doi: 10.1093/carcin/bgn163. Epub 2008 Jul 16.
Carcinogenesis. 2008.
PMID: 18632753
Free PMC article.
We observed an inverse association with risk for the AKR1C3 promoter SNP rs1937845 [OR (95% CI) for heterozygote and homozygote variant compared with common homozygote genotype were 0.86 (0.70-1.06) and 0.74 (0.57-0.96), respectively; P for trend = 0.02]. Interestingly, ge …
We observed an inverse association with risk for the AKR1C3 promoter SNP rs1937845 [OR (95% CI) for heterozygote and homozygote varia …