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Page 1
Pulmonary large-cell neuroendocrine carcinoma (LCNEC).
Hage R, Seldenrijk K, de Bruin P, van Swieten H, van den Bosch J. Hage R, et al. Eur J Cardiothorac Surg. 2003 Apr;23(4):457-60. doi: 10.1016/s1010-7940(02)00837-0. Eur J Cardiothorac Surg. 2003. PMID: 12694759 Review.
OBJECTIVE: The experiences on the treatment of seven consecutive patients with large-cell neuroendocrine carcinoma (LCNEC) were studied, observed over 6 years from 1992. Since LCNEC was recognized as a separate histological entity, only very few series have been reported. …
OBJECTIVE: The experiences on the treatment of seven consecutive patients with large-cell neuroendocrine carcinoma (LCNEC) were studied, …
Molecular Subtypes of Pulmonary Large-cell Neuroendocrine Carcinoma Predict Chemotherapy Treatment Outcome.
Derks JL, Leblay N, Thunnissen E, van Suylen RJ, den Bakker M, Groen HJM, Smit EF, Damhuis R, van den Broek EC, Charbrier A, Foll M, McKay JD, Fernandez-Cuesta L, Speel EM, Dingemans AC; PALGA-Group. Derks JL, et al. Clin Cancer Res. 2018 Jan 1;24(1):33-42. doi: 10.1158/1078-0432.CCR-17-1921. Epub 2017 Oct 24. Clin Cancer Res. 2018. PMID: 29066508
We assessed whether these subtypes have a predictive value on chemotherapy outcome.Experimental Design: Clinical data and tumor specimens were retrospectively obtained from the Netherlands Cancer Registry and Pathology Registry. ...However, no difference was observed
We assessed whether these subtypes have a predictive value on chemotherapy outcome.Experimental Design: Clinical data and tumor speci …
Outcomes of Patients with Pulmonary Large Cell Neuroendocrine Carcinoma in I-IV Stage.
Lowczak A, Kolasinska-Cwikla A, Osowiecka K, Glinka L, Palucki J, Rzepko R, Doboszynska A, Cwikla JB. Lowczak A, et al. Medicina (Kaunas). 2021 Jan 28;57(2):118. doi: 10.3390/medicina57020118. Medicina (Kaunas). 2021. PMID: 33525370 Free PMC article.
The aim of this study was to assess the predictive factors of overall survival (OS) and progression-free survival (PFS) of pulmonary large cell neuroendocrine carcinoma (LCNEC) and combined LCNEC. ...
The aim of this study was to assess the predictive factors of overall survival (OS) and progression-free survival (PFS) of pulmona
Combined large cell neuroendocrine carcinoma: clinical characteristics, prognosis and postoperative management.
Yang Z, Wang Y, Chen Y, Qian F, Zhang Y, Hu M, Zhang W, Han B. Yang Z, et al. Eur J Cardiothorac Surg. 2022 Jul 11;62(2):ezac069. doi: 10.1093/ejcts/ezac069. Eur J Cardiothorac Surg. 2022. PMID: 35147672
OBJECTIVES: Combined large cell neuroendocrine carcinoma (C-LCNEC) is pulmonary large cell neuroendocrine carcinoma (LCNEC) mixed with other components, such as adenocarcinoma (AD) and squamous cell carcinoma (SCC). ...METHODS: We retrospectivel …
OBJECTIVES: Combined large cell neuroendocrine carcinoma (C-LCNEC) is pulmonary large cell neuroendocrine car
Spread Through Air Spaces in Stage I Pulmonary Large Cell Neuroendocrine Carcinoma.
Wan S, Shen Z, Hu S, Zhang L, Yu H, Chen Y, Wang J, Wang D, Zhang J, Zhang P. Wan S, et al. Ann Thorac Surg. 2024 Aug;118(2):385-393. doi: 10.1016/j.athoracsur.2024.01.002. Epub 2024 Jan 17. Ann Thorac Surg. 2024. PMID: 38242341
BACKGROUND: Pulmonary large cell neuroendocrine carcinoma (LCNEC) represents an exceptionally aggressive and infrequent variant within the realm of non-small cell lung cancer, necessitating surgical intervention as the primary therapeutic approa …
BACKGROUND: Pulmonary large cell neuroendocrine carcinoma (LCNEC) represents an exceptionally aggressive …
The role of postoperative radiotherapy (PORT) in pulmonary large cell neuroendocrine carcinoma (PLCNEC).
Gang Jin, Lili Xue, Xiang Song. Gang Jin, et al. Cancer Radiother. 2020 Jun;24(3):215-221. doi: 10.1016/j.canrad.2020.02.004. Epub 2020 Mar 7. Cancer Radiother. 2020. PMID: 32156456
PURPOSE: To assess the long-term survivals and related prognostic indicators of patients with pulmonary large cell neuroendocrine carcinoma (PLCNEC), and determine the prognostic value of post-operative radiotherapy in PLCNEC. ...Cox proportiona …
PURPOSE: To assess the long-term survivals and related prognostic indicators of patients with pulmonary large cell n
Efficacy of second-line chemotherapy in patients with pulmonary large cell neuroendocrine carcinoma.
Iida Y, Wakuda K, Kenmotsu H, Doshita K, Kodama H, Nishioka N, Miyawaki E, Miyawaki T, Mamesaya N, Kobayashi H, Omori S, Ko R, Ono A, Naito T, Murakami H, Sugino T, Gon Y, Takahashi T. Iida Y, et al. Sci Rep. 2024 Apr 1;14(1):7641. doi: 10.1038/s41598-024-58327-w. Sci Rep. 2024. PMID: 38561461 Free PMC article.
The efficacy of second-line chemotherapy in patients with pulmonary large cell neuroendocrine carcinoma (LCNEC) is unclear. This study aimed to evaluate the efficacy of second-line chemotherapy in patients with pulmonary LCNEC. ...No significant …
The efficacy of second-line chemotherapy in patients with pulmonary large cell neuroendocrine carcinoma ( …
A Semiquantitative Scoring System May Allow Biopsy Diagnosis of Pulmonary Large Cell Neuroendocrine Carcinoma.
Baine MK, Sinard JH, Cai G, Homer RJ. Baine MK, et al. Am J Clin Pathol. 2020 Jan 2;153(2):165-174. doi: 10.1093/ajcp/aqz149. Am J Clin Pathol. 2020. PMID: 31593583 Free PMC article.
OBJECTIVES: The aim of this study was to devise reproducible biopsy criteria for distinguishing pulmonary large cell neuroendocrine carcinoma (LCNEC) from non-small cell lung carcinoma (NSCLC). ...Tumors were scored based on morphology, neuroend …
OBJECTIVES: The aim of this study was to devise reproducible biopsy criteria for distinguishing pulmonary large cell
Clinicopathological characteristics and prognostic factors of pulmonary large cell neuroendocrine carcinoma: A large population-based analysis.
Yang Q, Xu Z, Chen X, Zheng L, Yu Y, Zhao X, Chen M, Luo B, Wang J, Sun J. Yang Q, et al. Thorac Cancer. 2019 Apr;10(4):751-760. doi: 10.1111/1759-7714.12993. Epub 2019 Feb 7. Thorac Cancer. 2019. PMID: 30734490 Free PMC article.
BACKGROUND: The study was conducted to compare the clinicopathological characteristics, survival outcomes, and metastatic patterns between pulmonary large cell neuroendocrine carcinoma (LCNEC) and other non-small cell lung cancer (ONSCLC), and t …
BACKGROUND: The study was conducted to compare the clinicopathological characteristics, survival outcomes, and metastatic patterns between …
Pulmonary large cell neuroendocrine carcinoma (LCNEC): a population-based study addressing recent molecular-genetic advances and emerging therapeutic approaches.
Khan J, Yasinzai AQK, Matosz S, Khan M, Heneidi S, Mesa H, Chauhan A, Del Rivero J, Karim NA, Ullah A. Khan J, et al. Clin Exp Med. 2023 Nov;23(7):3947-3955. doi: 10.1007/s10238-023-01071-8. Epub 2023 Apr 15. Clin Exp Med. 2023. PMID: 37060529
Most patients die within 2 years. The best predictor of survival is surgery with chemotherapy. Given its dismal prognosis, new treatment guidelines are needed for this aggressive cancer....
Most patients die within 2 years. The best predictor of survival is surgery with chemotherapy. Given its dismal prognosis, new treatm …
39 results