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61 results

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Page 1
Pulmonary Large Cell Neuroendocrine Carcinoma.
Yang L, Fan Y, Lu H. Yang L, et al. Pathol Oncol Res. 2022 Oct 11;28:1610730. doi: 10.3389/pore.2022.1610730. eCollection 2022. Pathol Oncol Res. 2022. PMID: 36304941 Free PMC article. Review.
This review focuses on the epidemiological features, imaging studies, pathology, diagnosis, treatment, and prognosis of LCNEC....
This review focuses on the epidemiological features, imaging studies, pathology, diagnosis, treatment, and prognosis of LCNEC....
Pulmonary large-cell neuroendocrine carcinoma (LCNEC).
Hage R, Seldenrijk K, de Bruin P, van Swieten H, van den Bosch J. Hage R, et al. Eur J Cardiothorac Surg. 2003 Apr;23(4):457-60. doi: 10.1016/s1010-7940(02)00837-0. Eur J Cardiothorac Surg. 2003. PMID: 12694759 Review.
CONCLUSIONS: LCNEC is a high-grade neuroendocrine tumor with a poor prognosis. In our patients, after surgical resection or multimodality treatment, all have developed widespread metastatic disease with a rapidly fatal course. Due to the rarity of this tumor, the in …
CONCLUSIONS: LCNEC is a high-grade neuroendocrine tumor with a poor prognosis. In our patients, after surgical resection or multimoda …
Large cell neuroendocrine carcinoma of the lungs: case report and literature review.
Han Y, Pang L, Huang J, Chen J. Han Y, et al. Ann Palliat Med. 2020 Sep;9(5):3705-3709. doi: 10.21037/apm-20-1667. Ann Palliat Med. 2020. PMID: 33065807 Free article. Review.
Pulmonary large cell neuroendocrine carcinoma (LCNEC) is a rare but destructive tumor type, accounting for approximately 1% of all lung cancers, associated with poor prognosis. LCNEC is challenging diagnosing using biopsy specimens. While current LCNEC therapies include su …
Pulmonary large cell neuroendocrine carcinoma (LCNEC) is a rare but destructive tumor type, accounting for approximately 1% of all lung canc …
Molecular Subtypes of Pulmonary Large-cell Neuroendocrine Carcinoma Predict Chemotherapy Treatment Outcome.
Derks JL, Leblay N, Thunnissen E, van Suylen RJ, den Bakker M, Groen HJM, Smit EF, Damhuis R, van den Broek EC, Charbrier A, Foll M, McKay JD, Fernandez-Cuesta L, Speel EM, Dingemans AC; PALGA-Group. Derks JL, et al. Clin Cancer Res. 2018 Jan 1;24(1):33-42. doi: 10.1158/1078-0432.CCR-17-1921. Epub 2017 Oct 24. Clin Cancer Res. 2018. PMID: 29066508
We assessed whether these subtypes have a predictive value on chemotherapy outcome.Experimental Design: Clinical data and tumor specimens were retrospectively obtained from the Netherlands Cancer Registry and Pathology Registry. ...
We assessed whether these subtypes have a predictive value on chemotherapy outcome.Experimental Design: Clinical data and tumor speci …
Pulmonary large cell neuroendocrine carcinoma: its place in the spectrum of pulmonary carcinoma.
Iyoda A, Hiroshima K, Nakatani Y, Fujisawa T. Iyoda A, et al. Ann Thorac Surg. 2007 Aug;84(2):702-7. doi: 10.1016/j.athoracsur.2007.03.093. Ann Thorac Surg. 2007. PMID: 17643676 Review.
Since the first report of LCNEC in 1991, many authors have reported that LCNECs are aggressive tumors and that patients with LCNECs have a very poor prognosis. Although LCNEC is categorized as a variant of large cell carcinoma, the biological behaviors of LCNEC tumors rese …
Since the first report of LCNEC in 1991, many authors have reported that LCNECs are aggressive tumors and that patients with LCNECs have a v …
Outcomes of Patients with Pulmonary Large Cell Neuroendocrine Carcinoma in I-IV Stage.
Lowczak A, Kolasinska-Cwikla A, Osowiecka K, Glinka L, Palucki J, Rzepko R, Doboszynska A, Cwikla JB. Lowczak A, et al. Medicina (Kaunas). 2021 Jan 28;57(2):118. doi: 10.3390/medicina57020118. Medicina (Kaunas). 2021. PMID: 33525370 Free PMC article.
Background and Objectives: Large cell neuroendocrine cancer is characterised by poor prognosis. The standard of treatment is still not established. The aim of this study was to assess the predictive factors of overall survival (OS) and progression-free survival (PFS …
Background and Objectives: Large cell neuroendocrine cancer is characterised by poor prognosis. The standard of treatment is still no …
Combined large cell neuroendocrine carcinoma: clinical characteristics, prognosis and postoperative management.
Yang Z, Wang Y, Chen Y, Qian F, Zhang Y, Hu M, Zhang W, Han B. Yang Z, et al. Eur J Cardiothorac Surg. 2022 Jul 11;62(2):ezac069. doi: 10.1093/ejcts/ezac069. Eur J Cardiothorac Surg. 2022. PMID: 35147672
However, there was no significant difference in disease-free survival and overall survival between the 2 groups (before matching: P = 0.79 and P = 0.85; after matching: P = 0.87 and P = 0.48), while adjuvant chemotherapy (P = 0.019 and P = 0.043) was an independent predictor …
However, there was no significant difference in disease-free survival and overall survival between the 2 groups (before matching: P = 0.79 a …
The role of postoperative radiotherapy (PORT) in pulmonary large cell neuroendocrine carcinoma (PLCNEC).
Gang Jin, Lili Xue, Xiang Song. Gang Jin, et al. Cancer Radiother. 2020 Jun;24(3):215-221. doi: 10.1016/j.canrad.2020.02.004. Epub 2020 Mar 7. Cancer Radiother. 2020. PMID: 32156456
PURPOSE: To assess the long-term survivals and related prognostic indicators of patients with pulmonary large cell neuroendocrine carcinoma (PLCNEC), and determine the prognostic value of post-operative radiotherapy in PLCNEC. ...Multivariate analysis revealed that …
PURPOSE: To assess the long-term survivals and related prognostic indicators of patients with pulmonary large cell neuroendocrine car …
Spread Through Air Spaces in Stage I Pulmonary Large Cell Neuroendocrine Carcinoma.
Wan S, Shen Z, Hu S, Zhang L, Yu H, Chen Y, Wang J, Wang D, Zhang J, Zhang P. Wan S, et al. Ann Thorac Surg. 2024 Aug;118(2):385-393. doi: 10.1016/j.athoracsur.2024.01.002. Epub 2024 Jan 17. Ann Thorac Surg. 2024. PMID: 38242341
Univariate and multivariate analyses both unveiled that spread through air spaces (STAS) status emerged as an independent prognostic determinant for both DFS (P = .003) and OS (P = .013), whereas histologic subtype independently predicted OS (P = .011). ...CONCLUSIO …
Univariate and multivariate analyses both unveiled that spread through air spaces (STAS) status emerged as an independent prognostic …
Clinicopathological characteristics and prognostic factors of pulmonary large cell neuroendocrine carcinoma: A large population-based analysis.
Yang Q, Xu Z, Chen X, Zheng L, Yu Y, Zhao X, Chen M, Luo B, Wang J, Sun J. Yang Q, et al. Thorac Cancer. 2019 Apr;10(4):751-760. doi: 10.1111/1759-7714.12993. Epub 2019 Feb 7. Thorac Cancer. 2019. PMID: 30734490 Free PMC article.
BACKGROUND: The study was conducted to compare the clinicopathological characteristics, survival outcomes, and metastatic patterns between pulmonary large cell neuroendocrine carcinoma (LCNEC) and other non-small cell lung cancer (ONSCLC), and to identify the prognostic fa …
BACKGROUND: The study was conducted to compare the clinicopathological characteristics, survival outcomes, and metastatic patterns between p …
61 results