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Cumulative smoking dose affects the clinical outcomes of EGFR-mutated lung adenocarcinoma patients treated with EGFR-TKIs: a retrospective study.
Kim IA, Lee JS, Kim HJ, Kim WS, Lee KY. Kim IA, et al. BMC Cancer. 2018 Jul 28;18(1):768. doi: 10.1186/s12885-018-4691-0. BMC Cancer. 2018. PMID: 30055587 Free PMC article.
In the multivariate analysis adjusted for age, sex, performance status, stage, and timing of EGFR-TKIs, CSD was an independent predictive factor for disease progression (hazard ratio [HR], 4.00; 95% confidence interval [CI], 1.95-8.23; p = 0.012) and OS (HR, 3.9; 95% CI, 1 …
In the multivariate analysis adjusted for age, sex, performance status, stage, and timing of EGFR-TKIs, CSD was an independent predictive …
Presence of podoplanin-positive cancer-associated fibroblasts in surgically resected primary lung adenocarcinoma predicts a shorter progression-free survival period in patients with recurrences who received platinum-based chemotherapy.
Koriyama H, Ishii G, Yoh K, Neri S, Morise M, Umemura S, Matsumoto S, Niho S, Ohmatsu H, Tsuboi M, Goto K, Ochiai A. Koriyama H, et al. J Cancer Res Clin Oncol. 2015 Jul;141(7):1163-70. doi: 10.1007/s00432-014-1891-0. Epub 2014 Dec 2. J Cancer Res Clin Oncol. 2015. PMID: 25446816
CONCLUSIONS: The presence of podoplanin-positive CAFs in the primary tumor could be a predictor of a shorter PFS in recurrent lung adenocarcinoma patients who received chemotherapy. These findings suggest that stromal-cell-derived factors should be incorporated into pre …
CONCLUSIONS: The presence of podoplanin-positive CAFs in the primary tumor could be a predictor of a shorter PFS in recurrent lung ad …
An 81-Year-Old Man With Shortness of Breath After Chemotherapy and Radiation Therapy for Lung Cancer.
Mehta AK, Khan Z, Deepak J. Mehta AK, et al. Chest. 2019 Sep;156(3):e63-e67. doi: 10.1016/j.chest.2019.04.091. Chest. 2019. PMID: 31511162
He had been treated for a urinary tract infection twice over the past 3 weeks with prolonged courses of levofloxacin; while his urinary symptoms improved, his respiratory symptoms did not. ...
He had been treated for a urinary tract infection twice over the past 3 weeks with prolonged courses of levofloxacin; while his urina …
Thai female non-smoker with recurrent lung adenocarcinoma who has dramatic and prolonged response to gefitinib for over one year.
Charoentum C. Charoentum C. J Med Assoc Thai. 2006 Jun;89(6):882-6. J Med Assoc Thai. 2006. PMID: 16850692
This result is consistent with previous reports that the clinical characteristics of female, non-smoker and adenocarcinoma histology seem to predict response to gefitinib....
This result is consistent with previous reports that the clinical characteristics of female, non-smoker and adenocarcinoma histology seem to …