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ONTOLOGY REPORT - ANNOTATIONS

Term:histone H3K79 trimethyltransferase activity
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Accession:GO:0140956 term browser browse the term
Definition:Catalysis of the reaction: L-lysyl79-[histone H3] + 3 S-adenosyl-L-methionine = 3 H+ + N6,N6,N6-trimethyl-L-lysyl79-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of up to three methyl group to the lysine residue at position 79 of the histone H3 protein, producing H3K79me3.
Synonyms:exact_synonym: histone H3K79 trimethylase activity;   histone lysine N-trimethyltransferase activity (H3-K79 specific);   histone trimethylase activity (H3-K79 specific);   histone trimethyltransferase activity (H3-K79 specific)
 broad_synonym: histone H3-K79 trimethylation;   histone H3K79 trimethylation
 xref: EC:2.1.1.360;   RHEA:60328


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histone H3K79 trimethyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dot1l DOT1 like histone lysine methyltransferase enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 7:8,918,764...8,959,474
Ensembl chr 7:8,917,786...8,956,475 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20627
    catalytic activity 6029
      catalytic activity, acting on a protein 2508
        protein methyltransferase activity 104
          protein-lysine N-methyltransferase activity 69
            histone H3K79 methyltransferase activity 1
              histone H3K79 trimethyltransferase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 20627
    catalytic activity 6029
      transferase activity 2396
        transferase activity, transferring one-carbon groups 213
          methyltransferase activity 203
            S-adenosylmethionine-dependent methyltransferase activity 169
              lysine N-methyltransferase activity 69
                protein-lysine N-methyltransferase activity 69
                  histone H3K79 methyltransferase activity 1
                    histone H3K79 trimethyltransferase activity 1
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