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ONTOLOGY REPORT - ANNOTATIONS

Term:histone H4K12 methyltransferase activity
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Accession:GO:0140984 term browser browse the term
Definition:Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 12) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 12). This reaction is the addition of a methyl group to the lysine residue at position 12 of the histone H4 protein.
Comment:Note that in some species, the methyl group may be added to a lysine in a slightly different position of the histone H4 protein, but that this term still applies.
Synonyms:exact_synonym: histone H4 lysine 12-specific methyltransferase activity;   histone H4K12 methylation;   histone lysine N-methyltransferase activity (H4-K12 specific);   histone methylase activity (H4-K12 specific);   histone methyltransferase activity (H4-K12 specific)
 broad_synonym: histone H4K12 methylase activity


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histone H4K12 methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carm1 coactivator-associated arginine methyltransferase 1 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689 		JBrowse link
G N6amt1 N-6 adenine-specific DNA methyltransferase 1 enables ISO (PMID:31061526) RGD PMID:31061526 NCBI chr11:26,584,750...26,597,790
Ensembl chr11:26,584,724...26,608,248 		JBrowse link
G Ndufaf7 NADH:ubiquinone oxidoreductase complex assembly factor 7 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 6:16,108,630...16,119,810
Ensembl chr 6:16,103,003...16,119,810 		JBrowse link
G Prmt1 protein arginine methyltransferase 1 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345 		JBrowse link
G Prmt5 protein arginine methyltransferase 5 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr15:27,968,893...27,978,291
Ensembl chr15:27,968,910...27,978,296 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20627
    catalytic activity 6029
      catalytic activity, acting on a protein 2508
        protein methyltransferase activity 104
          protein-lysine N-methyltransferase activity 69
            histone H4K12 methyltransferase activity 5
Path 2
Term Annotations click to browse term
  molecular_function 20627
    catalytic activity 6029
      transferase activity 2396
        transferase activity, transferring one-carbon groups 213
          methyltransferase activity 203
            S-adenosylmethionine-dependent methyltransferase activity 169
              lysine N-methyltransferase activity 69
                protein-lysine N-methyltransferase activity 69
                  histone H4K12 methyltransferase activity 5
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