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Ontology Browser
Term:
histone H3K79 trimethyltransferase activity (GO:0140956)
Annotations: Rat: (1) Mouse: (0) Human: (1) Chinchilla: (0) Bonobo: (1) Dog: (0) Squirrel: (1) Pig: (1) Naked Mole-rat: (2) Green Monkey: (1)
Parent Terms Term With Siblings Child Terms
histone H3K79 dimethyltransferase activity 
histone H3K79 monomethyltransferase activity 
histone H3K79 trimethyltransferase activity  
Catalysis of the reaction: L-lysyl79-[histone H3] + 3 S-adenosyl-L-methionine = 3 H+ + N6,N6,N6-trimethyl-L-lysyl79-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of up to three methyl group to the lysine residue at position 79 of the histone H3 protein, producing H3K79me3.

Synonyms
Exact Synonyms: histone H3K79 trimethylase activity ;   histone lysine N-trimethyltransferase activity (H3-K79 specific) ;   histone trimethylase activity (H3-K79 specific) ;   histone trimethyltransferase activity (H3-K79 specific)
Broad Synonyms: histone H3-K79 trimethylation ;   histone H3K79 trimethylation
Xrefs: EC:2.1.1.360 ;   RHEA:60328
Definition Sources: PMID:15371351, RHEA:60328

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