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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
histone H3K4 dimethyltransferase activity  
histone H3K4 monomethyltransferase activity  
histone H3K4 trimethyltransferase activity  
Catalysis of the reaction: L-lysyl4-[histone H3] + 3 S-adenosyl-L-methionine = 2 H+ + N6,N6-trimethyl-L-lysyl4-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of three methyl groups to the unmethylated lysine residue at position 4 of histone H3, producing histone H3K4me3.

Synonyms
Exact Synonyms: histone H3K4 trimethylase activity ;   histone lysine N-trimethyltransferase activity (H3-K4 specific)
Broad Synonyms: histone H3-K4 trimethylation ;   histone H3K4 trimethylation
Xrefs: EC:2.1.1.354 ;   RHEA:60260
Definition Sources: PMID:18375658, RHEA:60260

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