Suv39h2 (SUV39H2 histone lysine methyltransferase) - Rat Genome Database

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Gene: Suv39h2 (SUV39H2 histone lysine methyltransferase) Rattus norvegicus
Analyze
Symbol: Suv39h2
Name: SUV39H2 histone lysine methyltransferase
RGD ID: 1306969
Description: Predicted to enable several functions, including cation binding activity; histone H3K9me2 methyltransferase activity; and ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in circadian rhythm; male meiotic nuclear division; and regulation of gene expression. Predicted to act upstream of or within cellular response to hypoxia; chromatin remodeling; and negative regulation of transcription by RNA polymerase II. Predicted to be located in heterochromatin. Predicted to be active in nucleus. Orthologous to human SUV39H2 (SUV39H2 histone lysine methyltransferase); PARTICIPATES IN histone modification pathway; homocysteine metabolic pathway; methionine cycle/metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; decabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: histone-lysine N-methyltransferase SUV39H2; LOC364785; suppressor of variegation 3-9 homolog 2; suppressor of variegation 3-9 homolog 2 (Drosophila)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81779,665,467 - 79,684,492 (+)NCBIGRCr8
mRatBN7.21774,756,290 - 74,775,332 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1774,756,306 - 74,775,332 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1778,209,501 - 78,228,542 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01782,057,802 - 82,076,828 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01776,092,937 - 76,111,981 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01778,762,897 - 78,782,016 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1778,762,991 - 78,782,016 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01780,406,940 - 80,425,965 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41785,875,954 - 85,894,979 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11785,886,805 - 85,903,145 (+)NCBI
Celera1774,141,962 - 74,160,987 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP)
calcitriol  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
cylindrospermopsin  (ISO)
decabromodiphenyl ether  (EXP)
dexamethasone  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
FR900359  (ISO)
glycerol 2-phosphate  (ISO)
hydrogen peroxide  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
methylmercury chloride  (ISO)
nickel atom  (ISO)
nitric oxide  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
perfluorooctanoic acid  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP)
succimer  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Histone lysine methylation dynamics: establishment, regulation, and biological impact. Black JC, etal., Mol Cell. 2012 Nov 30;48(4):491-507. doi: 10.1016/j.molcel.2012.11.006.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Targeting protein lysine methylation and demethylation in cancers. He Y, etal., Acta Biochim Biophys Sin (Shanghai). 2012 Jan;44(1):70-9. doi: 10.1093/abbs/gmr109.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression. O'Carroll D, etal., Mol Cell Biol 2000 Dec;20(24):9423-33.
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:10949293   PMID:15788566   PMID:20084102   PMID:21402781   PMID:23451023   PMID:24413057  


Genomics

Comparative Map Data
Suv39h2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81779,665,467 - 79,684,492 (+)NCBIGRCr8
mRatBN7.21774,756,290 - 74,775,332 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1774,756,306 - 74,775,332 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1778,209,501 - 78,228,542 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01782,057,802 - 82,076,828 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01776,092,937 - 76,111,981 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01778,762,897 - 78,782,016 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1778,762,991 - 78,782,016 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01780,406,940 - 80,425,965 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41785,875,954 - 85,894,979 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11785,886,805 - 85,903,145 (+)NCBI
Celera1774,141,962 - 74,160,987 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
SUV39H2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381014,878,866 - 14,904,315 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1014,878,820 - 14,904,315 (+)EnsemblGRCh38hg38GRCh38
GRCh371014,920,865 - 14,946,314 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361014,960,905 - 14,986,320 (+)NCBINCBI36Build 36hg18NCBI36
Build 341014,960,904 - 14,986,308NCBI
Celera1014,848,822 - 14,874,354 (+)NCBICelera
Cytogenetic Map10p13NCBI
HuRef1014,831,341 - 14,856,796 (+)NCBIHuRef
CHM1_11014,921,216 - 14,946,434 (+)NCBICHM1_1
T2T-CHM13v2.01014,892,831 - 14,918,279 (+)NCBIT2T-CHM13v2.0
Suv39h2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3923,456,852 - 3,476,085 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl23,456,852 - 3,476,068 (-)EnsemblGRCm39 Ensembl
GRCm3823,455,815 - 3,474,986 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl23,455,815 - 3,475,031 (-)EnsemblGRCm38mm10GRCm38
MGSCv3723,373,087 - 3,392,258 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3623,373,092 - 3,392,235 (-)NCBIMGSCv36mm8
Celera23,406,803 - 3,425,973 (-)NCBICelera
Cytogenetic Map2A1NCBI
cM Map21.95NCBI
Suv39h2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542919,503,197 - 19,528,027 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542919,503,197 - 19,526,454 (-)NCBIChiLan1.0ChiLan1.0
SUV39H2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2827,404,606 - 27,429,895 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11027,409,940 - 27,435,229 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01014,882,491 - 14,907,724 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11015,211,360 - 15,236,272 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1015,211,360 - 15,237,097 (+)Ensemblpanpan1.1panPan2
SUV39H2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1221,715,677 - 21,749,732 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl221,728,964 - 21,749,597 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha218,828,959 - 18,863,033 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0222,017,081 - 22,051,385 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl222,029,347 - 22,051,353 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1219,228,679 - 19,251,776 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0220,052,418 - 20,086,507 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0220,679,024 - 20,713,098 (-)NCBIUU_Cfam_GSD_1.0
Suv39h2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093446,893,110 - 6,922,105 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366131,443,629 - 1,467,229 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366131,443,663 - 1,467,776 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SUV39H2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1046,873,126 - 46,900,040 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11046,874,606 - 46,900,058 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21051,595,641 - 51,633,086 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SUV39H2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1914,900,503 - 14,924,017 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl914,900,945 - 14,923,447 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605120,439,417 - 20,464,204 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Suv39h2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624805597,406 - 618,969 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624805594,986 - 619,115 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Suv39h2
57 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:269
Count of miRNA genes:190
Interacting mature miRNAs:220
Transcripts:ENSRNOT00000020924
Prediction methods:Miranda, Pita, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358295Aocep1Aortic cell protein QTL 16.17e-07thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172393042179524188Rat
7411575Bw140Body weight QTL 14030.20.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
631502Cm26Cardiac mass QTL 263.71heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)176570358081153923Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175349882882479847Rat
7411577Bw141Body weight QTL 1410.001body mass (VT:0001259)body weight gain (CMO:0000420)176261951686533673Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)174992015486533673Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174054004180387013Rat
2317045Aia11Adjuvant induced arthritis QTL 114.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)176078142686533673Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172418489079524188Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
8694181Bw151Body weight QTL 1514.360.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
12904736Cm121Cardiac mass QTL 1210.043heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)177177462182479847Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175090909986022412Rat
7488963Bp369Blood pressure QTL 3690.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)175900564977910000Rat
1300129Rf25Renal function QTL 253.03blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)177100332581153923Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172393042179524188Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2393042179524188Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172393042179524188Rat
2302365Gluco40Glucose level QTL 404.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)175724684382046127Rat
2303580Gluco49Glucose level QTL 492blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)175004027186533673Rat

Markers in Region
RH133530  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21774,773,483 - 74,773,677 (+)MAPPERmRatBN7.2
Rnor_6.01778,780,168 - 78,780,361NCBIRnor6.0
Rnor_5.01780,424,117 - 80,424,310UniSTSRnor5.0
RGSC_v3.41785,893,131 - 85,893,324UniSTSRGSC3.4
Celera1774,159,139 - 74,159,332UniSTS
RH 3.4 Map17758.1UniSTS
Cytogenetic Map17q12.3UniSTS
ksks283  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21774,766,817 - 74,767,142 (+)MAPPERmRatBN7.2
Rnor_6.01778,773,503 - 78,773,827NCBIRnor6.0
Rnor_5.01780,417,452 - 80,417,776UniSTSRnor5.0
RGSC_v3.41785,886,466 - 85,886,790UniSTSRGSC3.4
Celera1774,152,474 - 74,152,798UniSTS
Cytogenetic Map17q12.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000020924   ⟹   ENSRNOP00000020924
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1774,756,306 - 74,775,332 (+)Ensembl
Rnor_6.0 Ensembl1778,762,991 - 78,782,016 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000077953   ⟹   ENSRNOP00000072847
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1778,764,506 - 78,779,545 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102582   ⟹   ENSRNOP00000096548
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1774,756,306 - 74,775,332 (+)Ensembl
RefSeq Acc Id: NM_001108883   ⟹   NP_001102353
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81779,665,467 - 79,684,492 (+)NCBI
mRatBN7.21774,756,306 - 74,775,332 (+)NCBI
Rnor_6.01778,762,991 - 78,782,016 (+)NCBI
Rnor_5.01780,406,940 - 80,425,965 (+)NCBI
RGSC_v3.41785,875,954 - 85,894,979 (+)RGD
Celera1774,141,962 - 74,160,987 (+)RGD
Sequence:
RefSeq Acc Id: XM_039095983   ⟹   XP_038951911
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81779,665,486 - 79,681,915 (+)NCBI
mRatBN7.21774,756,290 - 74,773,743 (+)NCBI
RefSeq Acc Id: XM_063276676   ⟹   XP_063132746
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81779,666,284 - 79,681,915 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001102353 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951911 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132746 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL78691 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000020924.3
  ENSRNOP00000096548.1
RefSeq Acc Id: NP_001102353   ⟸   NM_001108883
- UniProtKB: D3ZIH5 (UniProtKB/TrEMBL),   A6JM14 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072847   ⟸   ENSRNOT00000077953
Ensembl Acc Id: ENSRNOP00000020924   ⟸   ENSRNOT00000020924
RefSeq Acc Id: XP_038951911   ⟸   XM_039095983
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000096548   ⟸   ENSRNOT00000102582
RefSeq Acc Id: XP_063132746   ⟸   XM_063276676
- Peptide Label: isoform X2
Protein Domains
Chromo   Post-SET   Pre-SET   SET

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZIH5-F1-model_v2 AlphaFold D3ZIH5 1-481 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700581
Promoter ID:EPDNEW_R11105
Type:multiple initiation site
Name:Suv39h2_1
Description:suppressor of variegation 3-9 homolog 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01778,763,001 - 78,763,061EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306969 AgrOrtholog
BioCyc Gene G2FUF-8649 BioCyc
Ensembl Genes ENSRNOG00000015585 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020924.5 UniProtKB/TrEMBL
  ENSRNOT00000102582.1 UniProtKB/TrEMBL
Gene3D-CATH 2.170.270.10 UniProtKB/TrEMBL
  2.40.50.40 UniProtKB/TrEMBL
InterPro Chromo_domain UniProtKB/TrEMBL
  Chromo_domain/shadow UniProtKB/TrEMBL
  Chromodomain-like UniProtKB/TrEMBL
  Chromodomain_CS UniProtKB/TrEMBL
  H3K9_Histone-Lys_N-MTase UniProtKB/TrEMBL
  Histone_H3-K9_MeTrfase UniProtKB/TrEMBL
  Post-SET_dom UniProtKB/TrEMBL
  Pre-SET_dom UniProtKB/TrEMBL
  SET_dom UniProtKB/TrEMBL
  SET_dom_sf UniProtKB/TrEMBL
KEGG Report rno:364785 UniProtKB/TrEMBL
NCBI Gene 364785 ENTREZGENE
PANTHER HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H UniProtKB/TrEMBL
  HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H2 UniProtKB/TrEMBL
Pfam Chromo UniProtKB/TrEMBL
  Pre-SET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
PhenoGen Suv39h2 PhenoGen
PIRSF SUV39_SET UniProtKB/TrEMBL
PROSITE CHROMO_1 UniProtKB/TrEMBL
  CHROMO_2 UniProtKB/TrEMBL
  POST_SET UniProtKB/TrEMBL
  PRE_SET UniProtKB/TrEMBL
  SAM_MT43_SUVAR39_3 UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015585 RatGTEx
SMART CHROMO UniProtKB/TrEMBL
  PostSET UniProtKB/TrEMBL
  PreSET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
Superfamily-SCOP Chromodomain-like UniProtKB/TrEMBL
  SSF82199 UniProtKB/TrEMBL
UniProt A0A8I6GM48_RAT UniProtKB/TrEMBL
  A6JM14 ENTREZGENE, UniProtKB/TrEMBL
  D3ZIH5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-08-24 Suv39h2  SUV39H2 histone lysine methyltransferase  Suv39h2  suppressor of variegation 3-9 homolog 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-12-09 Suv39h2  suppressor of variegation 3-9 homolog 2  Suv39h2  suppressor of variegation 3-9 homolog 2 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Suv39h2  suppressor of variegation 3-9 homolog 2 (Drosophila)   Suv39h2_predicted  suppressor of variegation 3-9 homolog 2 (Drosophila) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Suv39h2_predicted  suppressor of variegation 3-9 homolog 2 (Drosophila) (predicted)      Symbol and Name status set to approved 70820 APPROVED