Breast cancer is the main cause of cancer-related death among women in Western
countries. Current research is focused on identifying antiapoptotic proteins which could be a
possible target for novel chemotherapeutic drugs. Secretory clusterin (sCLU) is an
extracellular chaperone that has been functionally implicated in DNA repair, cell-cycle
regulation, apoptotic cell death and tumorigenesis. The implication of sCLU in
carcinogenesis and the progression of breast carcinomas make it an interesting gene …