User profiles for Yan Daniel Zhao
Yan Daniel ZhaoUniversity of Oklahoma Health Sciences Center Verified email at ouhsc.edu Cited by 6421 |
Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer
…, L Watumull, YD Zhao… - Proceedings of the …, 2011 - National Acad Sciences
In the majority of cases, advanced prostate cancer responds initially to androgen deprivation
therapy by depletion of gonadal testosterone. The response is usually transient, and …
therapy by depletion of gonadal testosterone. The response is usually transient, and …
Nanosomes carrying doxorubicin exhibit potent anticancer activity against human lung cancer cells
Successful chemotherapeutic intervention for management of lung cancer requires an efficient
drug delivery system. Gold nanoparticles (GNPs) can incorporate various therapeutics; …
drug delivery system. Gold nanoparticles (GNPs) can incorporate various therapeutics; …
Strawberries improve pain and inflammation in obese adults with radiographic evidence of knee osteoarthritis
…, JR Barrett, BT Kurien, N Betts, TJ Lyons, YD Zhao… - Nutrients, 2017 - mdpi.com
Osteoarthritis (OA), the most common form of arthritis, is a significant public health burden in
US adults. Among its many risk factors, obesity is a key player, causing inflammation, pain, …
US adults. Among its many risk factors, obesity is a key player, causing inflammation, pain, …
A non-invasive liquid biopsy screening of urine-derived exosomes for miRNAs as biomarkers in endometrial cancer patients
…, K Moxley, R Ruskin, DN Dhanasekaran, YD Zhao… - The AAPS Journal, 2018 - Springer
Exosomes have great potential to serve as a source of diagnostic and prognostic biomarkers
for endometrial cancer (EC). Urine-derived exosomes from patients with EC and patients …
for endometrial cancer (EC). Urine-derived exosomes from patients with EC and patients …
Folate receptor-targeted nanoparticle delivery of HuR-RNAi suppresses lung cancer cell proliferation and migration
Background Human antigen R (HuR) is an RNA binding protein that is overexpressed in many
human cancers, including lung cancer, and has been shown to regulate the expression of …
human cancers, including lung cancer, and has been shown to regulate the expression of …
HuR-targeted small molecule inhibitor exhibits cytotoxicity towards human lung cancer cells
Human antigen (Hu) R is an RNA-binding protein whose overexpression in human cancer
correlates with aggressive disease, drug resistance, and poor prognosis. HuR inhibition has …
correlates with aggressive disease, drug resistance, and poor prognosis. HuR inhibition has …
Tumor-targeted Nanoparticle Delivery of HuR siRNA Inhibits Lung Tumor Growth In Vitro and In Vivo By Disrupting the Oncogenic Activity of the RNA-binding Protein …
Selective downregulation of the human antigen R (HuR) protein by siRNA may provide a
powerful approach for treating lung cancer. To this end, we investigated the efficacy of …
powerful approach for treating lung cancer. To this end, we investigated the efficacy of …
Exosomes as theranostics for lung cancer
Extensive research in genetics and genomics has revealed that lung cancer is a physiologically
complex and genetically heterogeneous disease. Although molecular targets that can …
complex and genetically heterogeneous disease. Although molecular targets that can …
Extensive traumatic anterior skull base fractures with cerebrospinal fluid leak: classification and repair techniques using combined vascularized tissue flaps
OBJECT This article introduces a classification scheme for extensive traumatic anterior skull
base fracture to help stratify surgical treatment options. The authors describe their multilayer …
base fracture to help stratify surgical treatment options. The authors describe their multilayer …
Preclinical efficacy and involvement of AKT, mTOR, and ERK kinases in the mechanism of sulforaphane against endometrial cancer
…, D Mangiaracina Benbrook, J Garland, Y Daniel Zhao… - Cancers, 2020 - mdpi.com
Sulforaphane exerts anti-cancer activity against multiple cancer types. Our objective was to
evaluate utility of sulforaphane for endometrial cancer therapy. Sulforaphane reduced …
evaluate utility of sulforaphane for endometrial cancer therapy. Sulforaphane reduced …