Izvorni kod stranice 3',5'-Ciklični-AMP fosfodiestaraza

{{Infobox Enzim
| Name = 3',5'-Ciklični-AMP fosfodiestaraza
| EC_number = 3.1.4.53
| CAS_number = 
| IUBMB_EC_number = 3/1/4/53
| GO_code = 
| image = 
| width = 
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}}
'''3',5'-Ciklični-AMP fosfodiestaraza''' ({{EC broj|3.1.4.53}}, ''cAMP-specifična fosfodiesteraza'', ''cAMP-specifična PDE'', ''PDE1'', ''PDE2A'', ''PDE2B'', ''PDE4'', ''PDE7'', ''PDE8'', ''PDEB1'', ''PDEB2'') je [[enzim]] sa sistematskim imenom ''3',5'-ciklična-AMP 5'-nukleotidohidrolaza''.<ref>{{cite journal | title = TcPDE4, a novel membrane-associated cAMP-specific phosphodiesterase from ''Trypanosoma cruzi'' |author = Alonso, G.D., Schoijet, A.C., Torres, H.N. and Flawi&aacute;, M.M. |journal = Mol. Biochem. Parasitol. |date = 2006 |volume = 145 |pages = 40-49 |pmid = 16225937}}</ref><ref>{{cite journal | title = DdPDE4, a novel cAMP-specific phosphodiesterase at the surface of ''Dictyostelium'' cells |author = Bader, S., Kortholt, A., Snippe, H. and Van Haastert, P.J. |journal = J. Biol. Chem. |date = 2006 |volume = 281 |pages = 20018-20026 |pmid = 16644729}}</ref><ref>{{cite journal | title = Cloning and characterization of a cAMP-specific phosphodiesterase (TbPDE2B) from ''Trypanosoma brucei'' |author = Rasc&oacute;n, A., Soderling, S.H., Schaefer, J.B. and Beavo, J.A. |journal = Proc. Natl. Acad. Sci. USA |date = 2002 |volume = 99 |pages = 4714-4719 |pmid = 11930017}}</ref><ref>{{cite journal | title = Cyclic nucleotide specific phosphodiesterases of ''Leishmania major'' |author = Johner, A., Kunz, S., Linder, M., Shakur, Y. and Seebeck, T. |journal = BMC Microbiol. |date = 2006 |volume = 6 |pages = #25-25 |pmid = 16522215}}</ref><ref>{{cite journal | title = Characterization of cyclic nucleotide phosphodiesterase isoforms associated to isolated cardiac nuclei |author = Lugnier, C., Keravis, T., Le Bec, A., Pauvert, O., Proteau, S. and Rousseau, E. |journal = Biochim. Biophys. Acta |date = 1999 |volume = 1472 |pages = 431-446 |pmid = 10564757}}</ref><ref>{{cite journal | title = Identification of the ''cpdA'' gene encoding cyclic 3&prime;,5&prime;-adenosine monophosphate phosphodiesterase in ''Escherichia coli'' |author = Imamura, R., Yamanaka, K., Ogura, T., Hiraga, S., Fujita, N., Ishihama, A. and Niki, H. |journal = J. Biol. Chem. |date = 1996 |volume = 271 |pages = 25423-25429 |pmid = 8810311}}</ref> Ovaj enzim [[Kataliza|katalizuje]] sledeću [[hemijska reakcija|hemijsku reakciju]]

: adenozin 3',5'-ciklična fosfat + H<sub>2</sub>O <math>\rightleftharpoons</math> [[Adenozin-monofosfat|AMP]]

Za dejstvo ovog enzim je neophodan jon Mg<sup>2+</sup> ili Mn<sup>2+</sup>.

== Reference ==
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== Literatura ==
{{refbegin|2}}
* {{PriceEnzymology3rd}}
* {{TooneAdvancesInEnzymology}}
* {{Branden ProteinStructure2nd}}
* {{SegelEnzymeKinetics}}
* {{CopelandEvaluationOfEnzymeInhibitors2nd}}
* {{MichalBiochemicalPathways}}
{{refend}}

== Spoljašnje veze ==
* {{MeshName|3',5'-cyclic-AMP+phosphodiesterase}}

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[[Kategorija:EC 3.1.4]]